Results 201 to 210 of about 78,864 (334)

Effects of Omidenepag Isopropyl Versus Latanoprost Eye Drops on Intraocular Pressure, Pupil Diameter, and Anterior Chamber Parameters in Normal Feline Eyes: A Pilot Study

open access: yesVeterinary Ophthalmology, EarlyView.
ABSTRACT Objectives This study aimed to compare the effect of the newly developed selective prostaglandin E2 receptor agonist, omidenepag isopropyl (OMDI), and latanoprost on intraocular pressure (IOP), pupil diameter (PD), and anterior chamber parameters in normal feline eyes.
Sang‐Eun Park   +5 more
wiley   +1 more source

Latanoprostene bunod ophthalmic solution 0.024% in the treatment of open-angle glaucoma: design, development, and place in therapy

open access: yesClinical Ophthalmology, 2018
Victoria M Addis, Eydie Miller-Ellis Division of Glaucoma, Scheie Eye Institute, University of Pennsylvania, Philadelphia, PA, USAAbstract: Latanoprostene bunod (LBN) 0.024%, a modified prostaglandin analog, was approved on November 2, 2017, for the ...
Addis VM, Miller-Ellis E
doaj  

Imaging Canine Post‐Trabecular Aqueous Outflow Pathways: Effect of Acute Intraocular Pressure Elevation in Normal Eyes

open access: yesVeterinary Ophthalmology, EarlyView.
ABSTRACT Purpose To investigate the relationship between increased intraocular pressure (IOP) and the structure of the post‐trabecular aqueous outflow tract of dogs. Methods Ex vivo aqueous angiography (AA) and anterior segment optical coherence tomography (OCT) were performed concurrently in 19 normal canine eyes, following cannulation and ...
Odalys Torné   +8 more
wiley   +1 more source

Topical Omidenepag Isopropyl Lowers Intraocular Pressure in Normal and Glaucomatous Cats: A Pilot Study

open access: yesVeterinary Ophthalmology, EarlyView.
ABSTRACT Purpose To evaluate the effects of topical prostaglandin E2 receptor 2 (EP2) agonist, omidenepag isopropyl (OMDI), on intraocular pressure (IOP) and pupil diameter (PD) in normal cats and cats with feline congenital glaucoma (FCG). Animals Studied Ten FCG cats and 8 normal cats.
Kazuya Oikawa   +5 more
wiley   +1 more source

Prospective in silico trials identify combined SK and K2P channel block as an effective strategy for atrial fibrillation cardioversion

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend In silico trials were conducted in 654 virtual patients with atrial fibrillation (AF) to assess the cardioversion efficacy of three pharmacological treatments: single SK and K2P channel block and combined SK+K2P channel inhibition. Left: representative virtual AF patient with the atria inside the torso.
Albert Dasí   +4 more
wiley   +1 more source

Atrial fibrosis in atrial fibrillation: Mechanisms, mapping techniques and clinical applications

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Summary of key aspects of atrial fibrosis in atrial fibrillation, highlighting atrial fibrosis as a hallmark of atrial fibrillation (AF). (1) Different types of fibrosis (blue), illustrating reparative and reactive fibrosis; (2) fibrosis detection techniques (green), illustrating late gadolinium enhancement cardiac magnetic ...
Caterina Vidal Horrach   +8 more
wiley   +1 more source

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