Results 51 to 60 of about 15,874 (252)
Studies from our laboratory have suggested that activation of αvβ3 integrin-mediated signaling could contribute to the fibrotic-like changes observed in primary open angle glaucoma (POAG) and glucocorticoid-induced glaucoma.
Mark S. Filla+3 more
doaj +1 more source
For the first time, Continuous Fiber‐Reinforced 3D printing is used to fabricate a foot prosthesis, exploring the flexibility in the design space granted by additive manufacturing, evaluating computationally and experimentally the effect of different design features on the mechanical and biomechanical response of the material, to locally tune the ...
Jacopo Romanò+10 more
wiley +1 more source
Intraocular pressure, which can cause glaucoma, is found to be affected by nocturnal sympathetic noradrenaline, which inhibits phagocytosis in trabecular meshwork cells through β1-aderenergic receptor mediated cAMP-EPAC-SHIP1 activation.
Keisuke Ikegami, Satoru Masubuchi
doaj +1 more source
Oxidative stress and antioxidants in the trabecular meshwork
Glaucoma is an age-dependent disease closely related to oxidative stress and is regarded as the second leading cause of irreversible blindness worldwide. In recent years, many studies have shown that morphological and functional abnormalities of the trabecular meshwork (TM) are closely related to glaucoma, especially with respect to oxidative stress ...
Yajuan Zheng, Mingxuan Wang
openaire +4 more sources
This study highlights the role of connexin43 (Cx43) in mediating glia activation and neuroinflammation in glaucoma. Using Cx43 knockout mice, it is shown that macroglial cells‐derived Cx43 modulates microglial activation, proliferation, migration, and polarization.
Guoli Zhao+17 more
wiley +1 more source
Endothelial nitric oxide synthase deficiency influences normal cell cycle progression and apoptosis in trabecular meshwork cells [PDF]
AIM: To clarify how the endothelial nitric oxide synthase (eNOS, NOS3) make effect on outflow facility through the trabecular meshwork (TM). METHODS: Inhibition of NOS3 gene expression in human TM cells were conducted by three siRNAs.
Qiong Liao+4 more
doaj +1 more source
The deficient TiO2 (DTO) and Barium titanate (BTO) heterojunction treats osteomyelitis through SDT. The spin‐polarization effect induced by the unpaired spin electrons in Ti atoms can expedite the transfer of ultrasonic piezoelectric charges in BTO, enhancing surface sonocatalytic efficiency.
Chaofeng Wang+10 more
wiley +1 more source
The trabecular meshwork in acute and chronic angle closure glaucoma.
PURPOSE: To determine the effect of acute and chronic primary angle closure glaucoma (PACG) on the trabecular meshwork. METHODS: Trabecular specimens of 16 consecutive patients with primary angle closure glaucoma (PACG)--6 acute PACG eyes, and 10 chronic
Sihota R+5 more
doaj
Background The pathophysiological changes occurring in the trabecular meshwork in primary open angle glaucoma are poorly understood, but are thought to include increased extracellular matrix deposition, trabecular meshwork cell apoptosis, inflammation ...
Esther L. Ashworth Briggs+4 more
doaj +1 more source
TIPARP is involved in the regulation of intraocular pressure
TIPARP, an inducible poly-ADP-ribose polymerase, is identified as a novel regulator of intraocular pressure through modulation of extracellular matrix and cell cytoskeleton proteins in trabecular meshwork cells.
Youjia Zhang+5 more
doaj +1 more source