Journal of Agromedicine and Medical Sciences (AMS), 2017 In primary open angle glaucoma, decrease of hyaluronic acid level is related to extracellular matrix deposition of trabecular meshwork. Extracellular matrix deposition will increase humor aqueous outflow resistance which in turn increase the intraocular ...
Cicih Komariah +2 more
doaj +1 more source
Canaloplasty in the Treatment of Open-Angle Glaucoma: A Review of Patient Selection and Outcomes. [PDF]
, 2018 Canaloplasty is a relatively new non-penetrating surgery for the reduction of intraocular pressure in patients affected by glaucoma. The technique uses a microcatheter to perform a 360 º cannulation of Schlemm's canal and leaves in place a tension suture
Brusini, Paolo +5 more
core +2 more sources
Protective Effects of Rapamycin on Trabecular Meshwork Cells in Glucocorticoid-Induced Glaucoma Mice
Frontiers in Pharmacology, 2020 Glucocorticoid-induced glaucoma (GIG) is a chronic optic neuropathy caused by systemic or topical glucocorticoid (GC) treatment, which could eventually lead to permanent vision loss.
Xiaolu Zhu +6 more
semanticscholar +1 more source
Implantation of trabecular micro-bypass stent using a novel “landing strip” technique [PDF]
International Journal of Ophthalmology, 2017 AIM: To describe a novel technique of creating a landing strip within the trabecular meshwork to guide trabecular micro-bypass stent (iStent) implantation in patients who underwent phacoemulsification.
Cindy X. Zheng +5 more
doaj +1 more source
Trabecular meshwork gene expression after selective laser trabeculoplasty.
PLoS ONE, 2011 BackgroundTrabecular meshwork and Schlemm's canal are the tissues appointed to modulate the aqueous humour outflow from the anterior chamber. The impairment of their functions drives to an intraocular pressure increase.
Alberto Izzotti +4 more
doaj +1 more source
Morphological changes in the iridocorneal angle and their relationship with intraocular pressure after infantile cataract surgery [PDF]
International Journal of Ophthalmology, 2022 AIM: To evaluate morphological changes in the iridocorneal angle after pediatric cataract surgery. METHODS: Children who underwent primary infantile cataract surgery were included and 64 eyes from 41 children, including 18 with unilateral cataracts (18 ...
Dan-Dan Wang +5 more
doaj +1 more source
A comparative study of the elastic fibre system within the mouse and human cornea [PDF]
, 2018 The cornea relies on its organised extracellular matrix for maintaining transparency and biomechanical strength. Studies have identified an elastic fibre system within the human posterior cornea, thought to allow for slight deformations in response to ...
Feneck, Eleanor M. +3 more
core +2 more sources
Extracellular matrix in the trabecular meshwork [PDF]
Experimental Eye Research, 2008 The extracellular matrix (ECM) of the trabecular meshwork (TM) is thought to be important in regulating intraocular pressure (IOP) in both normal and glaucomatous eyes. IOP is regulated primarily by a fluid resistance to aqueous humor outflow. However, neither the exact site nor the identity of the normal resistance to aqueous humor outflow has been ...
Ted S, Acott, Mary J, Kelley
openaire +2 more sources
Rho- Kinase Inhibitor Y-27632 Decreases the Thickness of Trabecular Meshwork in Juvenile Rats Mod-el Injected with Sodium Hyaluronate [PDF]
, 2018 Most glaucoma drugs lower the intraocular pressure (IOP) by decreasing the aqueous humor production and increasing the outflow through uveoscleral pathway. None of these drugs work mainly on increasing outflow through the trabecular pathway. Consequently,
Effendi, M. (Ma\u27sum) +3 more
core +1 more source
RNA interference as a gene silencing therapy for mutant
Diagnostic Pathology, 2009 Background Primary open-angle glaucoma (POAG) is the most common form of glaucoma which is an irreversible blind leading disease and lacks effective remedies.
Sun Xinghuai +3 more
doaj +1 more source