Results 1 to 10 of about 186,745 (257)

Titanium dioxide particles frequently present in face masks intended for general use require regulatory control

Scientific Reports, 2022
Although titanium dioxide (TiO2) is a suspected human carcinogen when inhaled, fiber-grade TiO2 (nano)particles were demonstrated in synthetic textile fibers of face masks intended for the general public.
Eveline Verleysen, Marina Ledecq, Lisa Siciliani, Karlien Cheyns, Christiane Vleminckx, Marie-Noelle Blaude, Sandra De Vos, Frédéric Brassinne, Frederic Van Steen, Régis Nkenda, Ronny Machiels, Nadia Waegeneers, Joris Van Loco, Jan Mast   +13 more
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Association between gut microbiota and longevity: a genetic correlation and mendelian randomization study

BMC Microbiology, 2022
Background Longevity is one of the most complex phenotypes, and its genetic basis remains unclear. This study aimed to explore the genetic correlation and potential causal association between gut microbiota and longevity.
Dan He, Li Liu, Zhen Zhang, Xuena Yang, Yumeng Jia, Yan Wen, Shiqiang Cheng, Peilin Meng, Chun’e Li, Huijie Zhang, Chuyu Pan, Feng Zhang   +11 more
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Physicochemical Characterization of the Pristine E171 Food Additive by Standardized and Validated Methods

Nanomaterials, 2020
E171 (titanium dioxide) is a food additive that has been authorized for use as a food colorant in the European Union. The application of E171 in food has become an issue of debate, since there are indications that it may alter the intestinal barrier ...
Eveline Verleysen, Nadia Waegeneers, Frédéric Brassinne, Sandra De Vos, Isaac Ojea Jimenez, Stella Mathioudaki, Jan Mast   +6 more
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The interaction of early life factors and depression-associated loci affecting the age at onset of the depression

Translational Psychiatry, 2022
Multiple previous studies explored the associations between early life factors and the age at onset of the depression. However, they only focused on the influence of environmental or genetic factors, without considering the interactions between them ...
Yujing Chen, Chuyu Pan, Shiqiang Cheng, Chun’e Li, Huijie Zhang, Zhen Zhang, Jingxi Zhang, Yao Yao, Peilin Meng, Xuena Yang, Li Liu, Bolun Cheng, Yumeng Jia, Yan Wen, Feng Zhang   +14 more
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Traumatic events during childhood and its risks to substance use in adulthood: an observational and genome-wide by environment interaction study in UK Biobank

Translational Psychiatry, 2021
We aimed to explore the underlying genetic mechanisms of traumatic events during childhood affecting the risks of adult substance use in present study. Using UK Biobank cohort, linear regression model was first applied to assess the relationships between
Shiqiang Cheng, Yan Wen, Li Liu, Bolun Cheng, Chujun Liang, Jing Ye, Xiaomeng Chu, Yao Yao, Yumeng Jia, Om Prakash Kafle, Feng Zhang   +10 more
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Associations between genetic loci, environment factors and mental disorders: a genome-wide survival analysis using the UK Biobank data

Translational Psychiatry, 2022
It is well-accepted that both environment and genetic factors contribute to the development of mental disorders (MD). However, few genetic studies used time-to-event data analysis to identify the susceptibility genetic variants associated with MD and ...
Peilin Meng, Jing Ye, Xiaomeng Chu, Bolun Cheng, Shiqiang Cheng, Li Liu, Xuena Yang, Chujun Liang, Feng Zhang   +8 more
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Association between birth by caesarian section and anxiety, self-harm: a gene-environment interaction study using UK Biobank data

BMC Psychiatry, 2023
Background Limited efforts have been paid to explore the underlying genetic mechanisms of birth by caesarian section (CS) affecting the risks of adult anxiety and self-harm. Methods Using UK Biobank cohort, the logistic regression model was first applied
Yumeng Jia, Shiqiang Cheng, Li Liu, Bolun Cheng, Chujun Liang, Jing Ye, Xiaomeng Chu, Yao Yao, Yan Wen, Om Prakash Kafle, Feng Zhang   +10 more
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Assessing the effect of interaction between gut microbiome and inflammatory bowel disease on the risks of depression

Brain, Behavior, & Immunity - Health, 2022
Background: Gut microbiome and inflammatory bowel disease (IBD) are implicated in the development of depression, but the effect of their interactions on the risk of depression remains unclear.
Xiaoyue Qin, Chuyu Pan, Qingqing Cai, Yijing Zhao, Dan He, Wenming Wei, Na Zhang, Sirong Shi, Xiaoge Chu, Feng Zhang   +9 more
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Assessing the effect of interaction between C-reactive protein and gut microbiome on the risks of anxiety and depression

Molecular Brain, 2021
Cumulative evidence shows that gut microbiome can influence brain function and behavior via the inflammatory processes. However, the role of interaction between gut dysbiosis and C-reactive protein (CRP) in the development of anxiety and depression ...
Yujing Chen, Peilin Meng, Shiqiang Cheng, Yumeng Jia, Yan Wen, Xuena Yang, Yao Yao, Chuyu Pan, Chun’e Li, Huijie Zhang, Jingxi Zhang, Zhen Zhang, Feng Zhang   +12 more
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An integrative analysis of genome-wide association study and regulatory SNP annotation datasets identified candidate genes for bipolar disorder

International Journal of Bipolar Disorders, 2020
Background Bipolar disorder (BD) is a complex mood disorder. The genetic mechanism of BD remains largely unknown. Methods We conducted an integrative analysis of genome-wide association study (GWAS) and regulatory SNP (rSNP) annotation datasets ...
Xin Qi, Yan Wen, Ping Li, Chujun Liang, Bolun Cheng, Mei Ma, Shiqiang Cheng, Lu Zhang, Li Liu, Om Prakash Kafle, Feng Zhang   +10 more
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