Results 81 to 90 of about 376,527 (305)

Temporal moments of a tracer pulse in a perfectly parallel flow system [PDF]

, 2002
Perfectly parallel groundwater transport models partition water flow into isolated one-dimensional stream tubes which maintain total spatial correlation of all properties in the direction of flow.
Bardsley, W. Earl
core   +2 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

ATLAS: Airborne Tunable Laser Absorption Spectrometer for stratospheric trace gas measurements [PDF]

The ATLAS instrument is an advanced technology diode laser based absorption spectrometer designed specifically for stratospheric tracer studies. This technique was used in the acquisition of N2O tracer data sets on the Airborne Antarctic Ozone Experiment
Loewenstein, Max, Podolske, James R., Strahan, Susan E.   +2 more
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Chemical and photonic interactions in vitro and in vivo between fluorescent tracer and nanoparticle-based scavenger for enhanced molecular imaging

Materials Today Bio, 2019
We hereby present a concept of scavenging excess imaging agent prior to a diagnostic imaging session, consequently allowing for enhanced contrast of signals originating from the tissue area of interest to the signals originating from systemic imaging ...
T. Gulin-Sarfraz, E. Pryazhnikov, J. Zhang, L. Khiroug, J.M. Rosenholm   +4 more
doaj   +1 more source

Diagnostics of the tropical tropopause layer from in-situ observations and CCM data [PDF]

, 2009
A suite of diagnostics is applied to in-situ aircraft measurements and one Chemistry-Climate Model (CCM) data to characterize the vertical structure of the Tropical Tropopause Layer (TTL).
Cagnazzo, Chiara, Cairo, Francesco, D'Amato, Francesco, Di Donfrancesco, Guido, Fierli, Federico, Manzini, Elisa, Palazzi, Elisa, Ravegnani, Fabrizio, Schiller, Cornelius, Volk, C.-Michael   +9 more
core  

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Impact of infusion conditions and anesthesia on CSF tracer dynamics in mouse brain

Fluids and Barriers of the CNS
Background Dynamic contrast-enhanced MRI has become an invaluable tool for mapping cerebrospinal fluid (CSF) flow and delineating solute transport pathways in the brain.
Yuran Zhu, Junqing Zhu, Chenxin Ni, Anbang Chen, Longshun Li, Yue Gao, Andrew J. Shoffstall, Xin Yu   +7 more
doaj   +1 more source

Can uptake length in strams be determined by nutrient addition experiments? Results from an interbiome comparison study [PDF]

, 2002
Nutrient uptake length is an important parnmeter tor quantifying nutrient cycling in streams. Although nutrient tracer additions are the preierred method for measuring uptake length under ambient nutrient concentrations, short-term nutrient addition ...
Bowden, William B., Dodds, Walter K., Gregory, Stanley V., Grimm, Nancy B., Meriam, J. L., Meyer, Judy L., Mulholland, Patrick J., Peterson, Bruce J., Tanks, Jennifer L., Valett, H. Maurice, Webster, Jackson R., Wollheim, Wilfred M.   +11 more
core   +2 more sources

Use of rare earth oxides as tracers to identify sediment source areas for agricultural hillslopes [PDF]

, 2010
Understanding sediment sources is essential to enable more effective targeting of in-field mitigation approaches to reduce diffuse pollution from agricultural land.
Deasy, C., Quinton, John
core   +1 more source