Results 41 to 50 of about 31,742 (299)

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Method for Determining the Susceptibility of the Track

open access: yesApplied Sciences, 2022
This paper discusses real-world experiments in which selected ground imperfections were dynamically analysed in terms of track susceptibility for a linear and non-linear system.
Jerzy Kisilowski, Rafał Kowalik
doaj   +1 more source

An investigation of sleeper voids using a flexible track model integrated with railway multi-body dynamics

open access: yes, 2009
This article describes a flexible track system model (FTSM) that represents the track structure for a typical ballasted track, taking into account the flexibility of the rails, the sleeper mass and the resilience of the pad/fastening elements, as well as
Iwnicki, Simon D.   +6 more
core   +1 more source

CAR T‐Cell Therapy in Neurology: A Scoping Review of Neuro‐Oncology, Autoimmune Diseases & Neurotoxicity

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Chimeric antigen receptor (CAR) T‐cell therapy has been investigated in neurological diseases, encompassing both central nervous system malignancies and autoimmune disorders, thereby extending its application beyond hematological cancers.
Omar Alqaisi   +5 more
wiley   +1 more source

Influences of Under-Track Foundation Diseases on Track System

open access: yesBuildings
In order to study the influence of the under-track foundation disease on the track system, based on the CRTS II slab ballastless track in ABAQUS, this paper analyzes the influence of the overall temperature, temperature gradient, CA mortar layer ...
Jinbao Yao   +3 more
doaj   +1 more source

Application of Polyurethane Polymer and Assistant Rails to Settling the Abnormal Vehicle-Track Dynamic Effects in Transition Zone between Ballastless and Ballasted Track

open access: yesShock and Vibration, 2015
This paper describes tests on a transition section between ballasted and ballastless tracks in the Liupanshui-Zhanyi railway in China. The originally unsettled transition zone is exposed to sudden car shaking and a series of track transition problems ...
Caiyou Zhao   +3 more
doaj   +1 more source

Clinical Practice Guideline for Evaluation and Management of Peripheral Nervous System Manifestations in Sjögren's Disease

open access: yesArthritis Care &Research, EarlyView.
Objective Sjögren's disease is an autoimmune disorder that can impact multiple organ systems, including the peripheral nervous system (PNS). PNS manifestations, which can exist concurrently, include mononeuropathies, polyneuropathies, and autonomic nervous system neuropathies.
Anahita Deboo   +88 more
wiley   +1 more source

Does Long‐Term Lower Extremity Strength Training in Adults With Knee Osteoarthritis and Varus Alignment Reduce Knee Joint Loading During Gait?

open access: yesArthritis Care &Research, EarlyView.
Objective We examined whether 18 months of strength training in individuals with knee varus alignment and medial tibiofemoral osteoarthritis (OA) reduced knee joint loads during walking compared to an attention control group. Methods This study was a secondary analysis of a randomized clinical trial that compared the effects of strength training to a ...
Stephen P. Messier   +12 more
wiley   +1 more source

Artificial Intelligence in Systemic Sclerosis: Clinical Applications, Challenges, and Future Directions

open access: yesArthritis Care &Research, EarlyView.
Systemic sclerosis (SSc) is a rare autoimmune disease defined by immune dysregulation, vasculopathy, and progressive fibrosis of the skin and internal organs. Despite advances in care, major complications such as interstitial lung disease (ILD) and myocardial involvement remain the leading causes of morbidity and mortality.
Cristiana Sieiro Santos   +2 more
wiley   +1 more source

Effect of Different Combined Excitation on the Vibration Characteristics of Locomotive Gear Transmission

open access: yesIEEE Access, 2023
With the continuous improvement of locomotive operating speed, increasing axle load and increasing traction power, the dynamic excitation of wheel-rail interface and gear pair interface have become more and more intense, directly affecting the ...
Tao Zhang   +4 more
doaj   +1 more source

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