Results 231 to 240 of about 876,743 (305)

Efficacy and Safety Assessment of 5‐Fluorouracil, Irinotecan and Oxaliplatin‐Loaded Implants in Mouse and Pig Models for Pancreatic Cancer Therapy

open access: yesAdvanced Materials, EarlyView.
A novel FIRINOX‐loaded implant demonstrates controlled drug release, and potent therapeutic efficacy in pancreatic ductal adenocarcinoma mouse models with safety confirmed in a large‐animal pre‐clinical model. This innovative drug delivery platform offers a promising new treatment approach for non‐resectable, treatment‐resistant pancreatic cancer ...
Samantha J. Wade   +19 more
wiley   +1 more source

Elephant‐Skin‐Inspired Porous Cementitious Tiles with Programmable Crack Networks for Passive Cooling

open access: yesAdvanced Materials, EarlyView.
Elephant‐skin‐inspired crack networks are programmed in porous diatomaceous earth (DE)‐cement composites using substrate‐guided, stress‐concentration induced fracture. The resulting crack lattices act as capillary conduits that redistribute water, while the porous matrix stores moisture.
Qingya Huang   +5 more
wiley   +1 more source

Matrix Viscoelasticity Regulates Dendritic Cell Migration and Immune Priming

open access: yesAdvanced Materials, EarlyView.
Matrix viscoelasticity is a key mechanical feature of the tumor microenvironment but remains poorly understood in immune regulation. Here, we develop a tunable collagen platform to decouple viscoelasticity from stiffness and show that slow‐relaxing matrices constrain dendritic cell migration by limiting actomyosin‐driven matrix remodeling, thereby ...
Wei‐Hung Jung   +6 more
wiley   +1 more source

Autism outcomes and neurobehavioural markers in young children born to mothers with HIV in Kenya: a protocol for the Alama project. [PDF]

open access: yesBMJ Open
Oyungu E   +10 more
europepmc   +1 more source

Decoding THz‐Driven Dynamic Fingerprints of Ferroelectric Nanotwin Networks

open access: yesAdvanced Materials, EarlyView.
ABSTRACT Ultrafast polarization dynamics in ferroelectrics are of considerable interest for high‐speed tunable dielectrics and electro‐optics. Extended domain wall networks formed in ferroelectric twin nanodomains can support collective dynamics in the terahertz regime but require techniques that track polarization and strain evolution driven by ...
Xiaojiang Li   +20 more
wiley   +1 more source

Boosting Seawater Desalination by Ampere‐Level Nitrate Electroreduction On Defect‐Rich Ultrathin RuCu Alloy Nanostructures

open access: yesAdvanced Materials, EarlyView.
Defect engineering of ultrathin RuCu alloy nanostructures has been successfully achieved to enhance ammonia electrosynthesis under indutrial‐level current density. Simultaneously, the stable ampere‐level operation of nitrate electroreduction on defective RuCu nanostructures can drive seawater desalination at an ultrafast salt removal rate, offering an ...
Juan Wang   +15 more
wiley   +1 more source

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