Results 71 to 80 of about 181,272 (258)

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Hidden Online Surveillance: What Librarians Should Know to Protect Their Own Privacy and That of Their Patrons

Information Technology and Libraries, 2015
Librarians have a professional responsibility to protect the right to access information free from surveillance. This right is at risk from a new and increasing threat: the collection and use of non-personally identifying information such as IP addresses
Alexandre Fortier, Jacquelyn Burkell
doaj   +1 more source

EYE TRACKING IN EDUCATION

Professional Pedagogics
Relevance: Eye tracking, understood as a method for recording eye movements, gaze fixations, and selected oculomotor parameters, is now widely recognized as an important tool for investigating visual attention and cognitive processing. This article outlines the development of the method from pioneering studies of reading and visual perception to its ...
openaire   +1 more source

Self‐Regulated Learning Meets AI: Reinterpreting Self‐Regulation, Co‐Regulation, and Socially Shared Regulation in Human–AI Interaction

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Advancing artificial intelligence (AI) has transformed learning and work, yet higher education and professional development programs have not systematically equipped learners for AI‐prevalent environments. This lack of preparation creates uncertainty regarding control, responsibility, trust, and accountability.
Moon‐Heum Cho, Jerusalem Merkebu
wiley   +1 more source

Prediction of Skeleton Curves for Seismically Damaged RC Columns Based on a Data-Driven Machine-Learning Approach

Buildings
The skeleton curve plays a crucial role in evaluating the seismic capacity of damaged structures. The research explored the application of data-driven machine learning approaches to predict the skeleton curves of earthquake-damaged reinforced concrete ...
Pengyu Sun, Weiping Wen, Changhai Zhai, Yiran Li   +3 more
doaj   +1 more source

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina, Anna Marcé‐Grau, Barbara Masotto, Marta Codina, Lamia BenJemaa, Yasmina Elaribi, Mónica Martinez‐Gallo, Roger Colobran, Angel Sanchez‐Montañez, Irene Valenzuela, Yoshiko Murakami, Alfons Macaya   +11 more
wiley   +1 more source

Capturing Transformative Change in Education: The Challenge of Tracking Progress towards SDG Target

Policy and Practice: A Development Education Review, 2016
Target 4.7 of the Sustainable Development Goals (SDGs) aims to ‘ensure that all learners acquire the knowledge and skills needed to promote sustainable development’ (UN General Assembly, 2015: 17), thereby calling for transformative educational change ...
Susan Gallwey
doaj  

CSF Monoamine Metabolites and Cognitive Trajectory in Early Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Imaging and postmortem studies indicate that abnormalities in monoaminergic neurotransmission contribute to cognitive impairment in Parkinson's disease (PD). However, it remains uncertain if cerebrospinal fluid (CSF) monoamine metabolites can serve as biomarkers of cognitive decline in early PD.
Jing‐Yu Shao, Rong Li, Yu‐Xiang Jiao, Kai Ma, Hong‐Qi Yang, Zheng‐Yu Sun, Jie‐Wen Zhang, Shuai Chen   +7 more
wiley   +1 more source

Prevalence and genetic basis of Mycobacterium tuberculosis resistance to pretomanid in China

Annals of Clinical Microbiology and Antimicrobials
Background Pretomanid is a key component of new regimens for the treatment of drug-resistant tuberculosis (TB) which are being rolled out globally. However, there is limited information on the prevalence of pre-existing resistance to the drug. Methods To
Bing Zhao, Huiwen Zheng, Juliano Timm, Zexuan Song, Shaojun Pei, Ruida Xing, Yajie Guo, Ling Ma, Feina Li, Qing Li, Yan Li, Lin Huang, Chong Teng, Ni Wang, Aastha Gupta, Sandeep Juneja, Fei Huang, Yanlin Zhao, Xichao Ou   +18 more
doaj   +1 more source

Distinct genetic clusters in HIV-1 CRF01_AE-infected patients induced variable degrees of CD4+ T-cell loss

mBio
CRF01_AE strains have been shown to form multiple transmission clusters in China, and some clusters have disparate pathogenicity in Chinese men who have sex with men.
Kang Li, Huanhuan Chen, Jianjun Li, Yi Feng, Shujia Liang, Abdur Rashid, Meiliang Liu, Sisi Li, Qingfei Chu, Yuhua Ruan, Hui Xing, Guanghua Lan, Wentao Qiao, Yiming Shao   +13 more
doaj   +1 more source