Results 41 to 50 of about 314,235 (257)
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
Aging and Cancer, EarlyView.This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
The preventive maintenance trade-off model
Vojnotehnički Glasnik, 1997 The paper presents a general model for preventive maintenance of motor vehicles and other systems based on a 'trade-off' between maximum availability and minimum maintenance cost.
Svetomir Minić , Živan Arsenić
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Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers +19 more
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People and NatureGovernments worldwide are committed to eliminating hunger and conserving biodiversity, reflected in United Nations Sustainable Development Goals 2 (Zero Hunger) and 15 (Life on Land).
Abbie S. A. Chapman +12 more
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Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Introduction/Objective Acute intracranial stenting during endovascular thrombectomy (EVT) for ischemic stroke requires intraprocedural antiplatelet therapy (APT) to maintain patency. However, the hemorrhagic risk of combining APT with intravenous thrombolysis (IVT) remains uncertain.
Aaron Rodriguez‐Calienes +75 more
wiley +1 more source
LandFor a long time in the past, China has implemented a large number of “Grain for Green” projects (GFGPs) to improve the ecological environment. However, it is still unclear whether excessive GFGPs will exacerbate the trade-off of ecosystem services (ESs).
Yulong Dai +6 more
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Deep Learning Pose Estimation for Phenotyping of Co‐Occurring Hyperkinetic Movement Disorders
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To explore whether routine outpatient video combined with deep learning‐based pose estimation and clinically interpretable kinematic features can support multi‐label phenotyping of co‐occurring hyperkinetic movement disorders (HMDs).
Laura Cif +17 more
wiley +1 more source
A multi-level test of the seed number/size trade-off in two Scandinavian communities. [PDF]
PLoS ONE, 2018 Seed size is a fundamental life-history trait for plants. A seed number/size trade-off is assumed because the resources invested in reproduction are limited; however, such a trade-off is not always observed. This could be a consequence of the method used
Amparo Lázaro, Asier R Larrinaga
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Modern Management of Asymptomatic Carotid Stenosis: A Meta‐Analysis of CREST‐2, SPACE‐2, and ECST‐2
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Recent randomized trials (CREST‐2, SPACE‐2, and ECST‐2) have compared carotid revascularization (carotid endarterectomy [CEA] or carotid artery stenting [CAS]) plus contemporary medical therapy (CMT) versus CMT alone in asymptomatic carotid stenosis.
Aasim Ali +14 more
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The Bulletin of the Royal College of Surgeons of England, 2017 Cancer care cannot be improved at the expense of elective surgery.
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