Results 91 to 100 of about 2,485,749 (291)

TRADITION OF INDONESIAN ARTS AND NOW [PDF]

open access: yes, 2004
This paper is concerned with the study of Tradition of Indonesian Arts and Now. Indonesia is the largest archipelago in the world. It consists of more than thirteen thousand island, six thousand of which, covering sixty percent of its area size are ...
I Made , Bandem
core  

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Ideophones and sound symbolism in Northern Amis (Austronesian)

open access: yesLinguistic Typology at the Crossroads
This is a study of ideophones in Northern Amis, an East Formosan, Austronesian language of Taiwan. Ideophones depict sensory experiences, and they generally have the same phonological and phonotactic properties as other lexemes; however, some ideophones ...
Isabelle Bril
doaj   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Anti-obesity effects of Wumeishanzhayin: an integrated lipidomics and transcriptomics study

open access: yesFrontiers in Pharmacology
BackgroundThe global prevalence of adult obesity has increased significantly, affecting over 890 million adults worldwide. Wumeishanzhayin (WMSZY), a formulation derived from four medicinal and edible botanical drugs, has shown efficacy in alleviating ...
Xiao Huang   +7 more
doaj   +1 more source

Islamic Contributions to Science: Historical and Contemporary Issues [PDF]

open access: yes, 2012
The normative practice in the history of science in the West is to start with the Greeks and then jump to the European Renaissance, both studied as a background for the emergence of modern science in the seventeenth century.
Iqbal, Muzaffar
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

The Abbaco Tradition (1300-1500): its role in the development of European algebra [PDF]

open access: yes, 2008
Abbaco algebra is a coherent tradition of algebraic problem solving mostly based in the merchant cities of fourteenth and fifteenth-century Italy. This period is roughly situated between two important works dealing with algebra: the Liber Abbaci by ...
Heeffer, Albrecht
core   +1 more source

Home - About - Disclaimer - Privacy