Results 51 to 60 of about 269,097 (289)

Exploring the effects of measures of performance and calibration strategies on calibrating traffic microsimulation model: A quantitative analysis approach

IET Intelligent Transport Systems, 2023
In the subject of traffic microsimulation model (TMM) calibration, measure of performance (MoP) plays an essential role. However, due to the diversity of MoP types, choosing a MoP or MoP combination (usually used for multi‐criteria calibration strategy ...
Haoran Li, Zhenzhou Yuan, Siyuan Chen, Chuang Zhu   +3 more
doaj   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

Technology of intelligent driving radar perception based on driving brain

CAAI Transactions on Intelligence Technology, 2019
Radar is an important sensor to realise intelligent driving environment perception, enabling the detection of static obstacles and dynamic obstacles, and the tracking of a dynamic obstacle.
Hongbo Gao, Xinyu Zhang, Jianhui Zhao, Deyi Li   +3 more
doaj   +1 more source

Improving vehicle re‐identification using CNN latent spaces: Metrics comparison and track‐to‐track extension

IET Computer Vision, 2021
Herein, the problem of vehicle re‐identification using distance comparison of images in CNN latent spaces is addressed. First, the impact of the distance metrics, comparing performances obtained with different metrics is studied: the minimal Euclidean ...
Geoffrey Roman‐Jimenez, Patrice Guyot, Thierry Malon, Sylvie Chambon, Vincent Charvillat, Alain Crouzil, André Péninou, Julien Pinquier, Florence Sedes, Christine Sénac   +9 more
doaj   +1 more source

Fronthaul-Constrained Cloud Radio Access Networks: Insights and Challenges

, 2015
As a promising paradigm for fifth generation (5G) wireless communication systems, cloud radio access networks (C-RANs) have been shown to reduce both capital and operating expenditures, as well as to provide high spectral efficiency (SE) and energy ...
Lau, V., Peng, M., Poor, H. V., Wang, C.
core   +2 more sources

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Impact of connected vehicle environment on driving performance: A case of an extra‐long tunnel scenario

IET Intelligent Transport Systems, 2021
In view of the benefits and a promising prospect of the emerging connected vehicles (CV), more and more vehicles will be equipped with the in‐vehicle human‐machine interface (HMI). This study aims to assess the comprehensive impacts of HMIs on individual
Xin Chang, Jian Rong, Haijian Li, Yiping Wu, Xiaohua Zhao   +4 more
doaj   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Towards a digital twin for supporting multi-agency incident management in a smart city

Scientific Reports, 2022
Cost-effective on-demand computing resources can help to process the increasing number of large, diverse datasets generated from smart internet-enabled technology, such as sensors, CCTV cameras, and mobile devices, with high temporal resolution. Category
Kristina Wolf, Richard J. Dawson, Jon P. Mills, Phil Blythe, Jeremy Morley   +4 more
doaj   +1 more source