Results 51 to 60 of about 7,105,066 (255)

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

Enhanced motorway capacity estimation considering the impact of vehicle length on the fundamental diagram

open access: yesIET Intelligent Transport Systems
The ability to understand the underlying fundamentals of traffic flow behaviour facilitates improved planning and decision‐making for road operators.
Erik Giesen Loo   +3 more
doaj   +1 more source

Impact of connected vehicle environment on driving performance: A case of an extra‐long tunnel scenario

open access: yesIET Intelligent Transport Systems, 2021
In view of the benefits and a promising prospect of the emerging connected vehicles (CV), more and more vehicles will be equipped with the in‐vehicle human‐machine interface (HMI). This study aims to assess the comprehensive impacts of HMIs on individual
Xin Chang   +4 more
doaj   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

open access: yesFEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana   +5 more
wiley   +1 more source

Towards a digital twin for supporting multi-agency incident management in a smart city

open access: yesScientific Reports, 2022
Cost-effective on-demand computing resources can help to process the increasing number of large, diverse datasets generated from smart internet-enabled technology, such as sensors, CCTV cameras, and mobile devices, with high temporal resolution. Category
Kristina Wolf   +4 more
doaj   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

open access: yesFEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh   +2 more
wiley   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

open access: yesFEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain   +11 more
wiley   +1 more source

Cloud based large-scale real-time simulation for traffic engineering

open access: yes, 2016
Traffic engineering and smart road management are critical components of any modern city. Through simulations run on supercomputers, traffic engineers are able to study, plan and control road traffic in real-time.
Antonio Giardina (19116631)
core   +1 more source

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

open access: yesFEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen   +8 more
wiley   +1 more source

Two Modifications of MinSum Algorithm for Efficient System-Optimal Traffic Assignment

open access: yesAlgorithms
Traffic assignment in large urban areas is an old but increasingly important problem because of the rapid growth of the world population and traffic demands.
Nikica Hlupić   +3 more
doaj   +1 more source

Home - About - Disclaimer - Privacy