Results 51 to 60 of about 271,388 (282)
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
IET Computer Vision, 2021 Herein, the problem of vehicle re‐identification using distance comparison of images in CNN latent spaces is addressed. First, the impact of the distance metrics, comparing performances obtained with different metrics is studied: the minimal Euclidean ...
Geoffrey Roman‐Jimenez +9 more
doaj +1 more source
Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes
FEBS Open Bio, EarlyView.We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde +3 more
wiley +1 more source
Online Load Balancing for Network Functions Virtualization
, 2017 Network Functions Virtualization (NFV) aims to support service providers to deploy various services in a more agile and cost-effective way. However, the softwarization and cloudification of network functions can result in severe congestion and low ...
Binh, Huynh Thi Thanh +3 more
core +1 more source
FEBS Open Bio, EarlyView.We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa +2 more
wiley +1 more source
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
IET Intelligent Transport SystemsThe ability to understand the underlying fundamentals of traffic flow behaviour facilitates improved planning and decision‐making for road operators.
Erik Giesen Loo +3 more
doaj +1 more source
Towards a digital twin for supporting multi-agency incident management in a smart city
Scientific Reports, 2022 Cost-effective on-demand computing resources can help to process the increasing number of large, diverse datasets generated from smart internet-enabled technology, such as sensors, CCTV cameras, and mobile devices, with high temporal resolution. Category
Kristina Wolf +4 more
doaj +1 more source
Two-Hop Routing with Traffic-Differentiation for QoS Guarantee in Wireless Sensor Networks [PDF]
, 2014 This paper proposes a Traffic-Differentiated Two-Hop Routing protocol for Quality of Service (QoS) in Wireless Sensor Networks (WSNs). It targets WSN applications having different types of data traffic with several priorities.
Iyengar, S S +4 more
core +1 more source
YIPFα1A expression is regulated by multilayered molecular mechanisms
FEBS Open Bio, EarlyView.YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source