Results 101 to 110 of about 843,166 (295)
Machine Learning for Green Solvents: Assessment, Selection and Substitution
Advanced Science, EarlyView.Environmental regulations have intensified demand for green solvents, but discovery is limited by Solvent Selection Guides (SSGs) that quantify solvent sustainability. Training a machine learning model on GlaxoSmithKline SSG, a database of sustainability metrics for 10,189 solvents, GreenSolventDB is developed. Integrated with Hansen solubility metrics,
Rohan Datta +4 more
wiley +1 more source
The pediatrician and traffic safety
Jornal de Pediatria, 2005 To instruct children and teenagers about safe transportation and about their behavior as cyclists and pedestrians.The MEDLINE and LILACS databases were searched, using the following terms, from 1995 to 2005: traffic accidents, child, adolescent, morbidity, mortality, age, and gender. Scientific articles on morbidity and mortality from traffic accidents,
Renata D, Waksman, Regina M B K, Pirito
openaire +2 more sources
Risk management for traffic safety control [PDF]
, 2002 This paper offers a range of modelling ideas and techniques from mathematical statistics appropriate for analysing traffic accident data for the East region operation of CLP Power Hong Kong Limited and for the Hong Kong population in general.
Luczak, M.J., Wylie, J.
core
GPCRs in CAR‐T Cell Immunotherapy: Expanding the Target Landscape and Enhancing Therapeutic Efficacy
Advanced Science, EarlyView.Chimeric antigen receptor T cell therapy faces dual challenges of target scarcity and an immunosuppressive microenvironment in solid tumors. This review highlights how G protein‐coupled receptors can serve as both novel targets to expand the therapeutic scope and functional modules to enhance CAR‐T cell efficacy.
Zhuoqun Liu +11 more
wiley +1 more source
Multiple load recognition and fatigue assessment on longitudinal stop of railway freight car
Reviews on Advanced Materials Science, 2022 Zhou Wei +8 more
doaj +1 more source
Advanced Science, EarlyView.This study developed a hierarchical targeting nanoplatform, siTREM2@ETP‐PEOz‐OMVs, against triple‐negative breast cancer (TNBC) bone metastasis. It precisely delivers therapeutic siTREM2 to monocytes/macrophages within the metastatic niche. This intervention dually regulates cell fate: reprogramming immunosuppressive macrophages and inhibiting ...
Fanglu Chen +12 more
wiley +1 more source
Risk analysis in the surrounding areas of one-runway airports: A methodology to preliminary calculus of PSZs dimensions [PDF]
, 2016 The risk analysis of aeronautical accidents has been faced in several countries in order to plan the territory around airports. In the past, many accidents have had serious consequences in the surrounding of airports.
DI MASCIO, Paola, LOPRENCIPE, Giuseppe
core
Advanced Science, EarlyView.Emerging evidence suggests that intraneuronal Aβ accumulation represents an early pathogenic event in Alzheimer's disease (AD). Using Drosophila AD model, this study shows that a nonsecreted serine protease Yip7 physically interacts with Aβ. This causes intraneuronal Aβ accumulation but surprisingly reduces the associated neurotoxicity, arguing that ...
Jingyun Su +4 more
wiley +1 more source
Air Traffic Control Safety Indicators: What is Achievable?
, 2006 European Air Traffic Control is extremely safe. The drawback to this safety record is that it is very difficult to estimate what the ‘underlying’ accident rate for mid-air collisions is now, or to detect any changes over time.
Brooker, Peter
core
Advanced Science, EarlyView.Lysosome‐targeting chimeras (LYTACs) enable degradation of extracellular and membrane proteins via lysosomal trafficking. We report a novel IGF‐II mutant (Del1–7, Y27L) that selectively engages IGF‐IIR while avoiding IGF‐IR and IR‐A. mutIGF‐II–based LYTACs enhance target internalization and degradation and support a genetically encodable, all‐protein ...
Yuan Zhao +16 more
wiley +1 more source