Results 111 to 120 of about 4,055,099 (393)
Editorial on Impacts on Traffic Safety
International Journal of Transportation Science and Technology, 2012 ABSTRACTTraffic Safety has been internationally recognized as a primary strategic goal in many societies. Traffic safety concept is not limited to the reduction of road accidents issue. It aims to initiate/create the right road safety behavior by setting all necessary educational, engineering and medical programs and plans, traffic regulations, and ...
Abd al Majil, Bhzad Sidawi
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Rewiring Neuroimmunity: Nanoplatform Innovations for CNS Disease Therapy
Advanced Therapeutics, EarlyView.This review explores emerging nanoplatform strategies designed to modulate neuroimmune responses for treating central nervous system (CNS) disorders. It examines structural and microenvironmental barriers, advances in multifunctional and targeted nanotechnologies, and highlights clinical progress and translational challenges, offering insights into the
Muhammad Usman Akbar +7 more
wiley +1 more source
Journal of Advanced Transportation, 2018 In urban rail transit systems, train scheduling plays an important role in improving the transport capacity to alleviate the urban traffic pressure of huge passenger demand and reducing the operation costs for operators.
Miao Zhang +4 more
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, 2011 Includes copy of ethics approval. Original copy with original Partial Copyright Licence.
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Advanced Science, EarlyView.Current preclinical studies of AAV‐mediated gene therapy explore different strategies based on the characteristics of inner ear diseases. For genetic hearing loss, approaches include the replacement of a “good gene,” removal of a “bad gene,” or direct correction of mutations through base editing.
Fan Wu +7 more
wiley +1 more source
Do more trucks lead to more motor vehicle fatalities in European roads? Evaluating the impact of specific safety strategies. [PDF]
, 2015 Truck operations have recently become an important focus of academic research not only because road freight transport is a key part of logistics, but because trucks are usually associated with negative externalities including pollution, congestion and ...
Castillo Manzano, José I. +2 more
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Tumor‐Associated Glycan Exploits Adenosine Receptor 2A Signaling to Facilitate Immune Evasion
Advanced Science, EarlyView.This study identifies Globo H ceramide (GHCer) as a novel immune checkpoint molecule that suppresses the activation of conventional T lymphocytes while promoting the differentiation and function of regulatory T cells. The immunosuppressive effects of GHCer are mediated through the activation of the A2AR/cAMP/PKA pathway, which involves its interactions
Jing‐Yan Cheng +13 more
wiley +1 more source
Advanced Science, EarlyView.The TALENTs randomized controlled trial evaluates the potential of nucleotides supplementation as an anti‐aging intervention in older adults. After 19 weeks, nucleotides supplementation significantly reduces DNA methylation age, suggesting a delay in epigenetic aging, and improves insulin sensitivity without severe adverse events.
Shuyue Wang +9 more
wiley +1 more source
Advanced Science, EarlyView.Molecular mechanism study of self‐assembled M2pep‐Cs NPs/Plerixafor nanoparticles in targeting MΦ reprogramming by regulating the CXCL12–CXCR4 signaling pathway to enhance immune recognition and clearance of GC (Created by BioRender). Abstract Gastric carcinoma (GC) remains a major global health challenge, requiring novel therapeutic approaches.
Qianqian Cao +9 more
wiley +1 more source
Cogent Social Sciences, 2017 Road safety is a complex process that not only depends on technical and environmental improvements, but in a major part from human factors. In this sense, recent empirical studies have remarked the need to study the interaction between subject and laws ...
Francisco Alonso +3 more
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