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Lessons Learned from the Colorado Project to Comprehensively Combat Human Trafficking
Societies, 2023 Countering human trafficking at a statewide level requires a combination of knowledge from lived experience, inter-sector collaborations, and evidence-based tools to measure progress. Since 2010, the nonprofit Laboratory to Combat Human Trafficking (LCHT)
Annie Miller +6 more
doaj +1 more source
NF-κB activation enhances STING signaling by altering microtubule-mediated STING trafficking.
Cell Reports, 2023 It is widely known that stimulator of interferon genes (STING) can trigger nuclear factor κB (NF-κB) signaling. However, whether and how the NF-κB pathway affects STING signaling remains largely unclear.
Lulu Zhang +9 more
semanticscholar +1 more source
Insulin signalling and GLUT4 trafficking in insulin resistance
Biochemical Society Transactions, 2023 Insulin-stimulated glucose uptake into muscle and adipose tissue is vital for maintaining whole-body glucose homeostasis. Insulin promotes glucose uptake into these tissues by triggering a protein phosphorylation signalling cascade, which converges on ...
Julian van Gerwen +2 more
semanticscholar +1 more source
Phospholipase D3 degrades mitochondrial DNA to regulate nucleotide signaling and APP metabolism
Nature Communications, 2023 Phospholipase D3 (PLD3) polymorphisms are linked to late-onset Alzheimer’s disease (LOAD). Being a lysosomal 5’-3’ exonuclease, its neuronal substrates remained unknown as well as how a defective lysosomal nucleotide catabolism connects to AD ...
Zoë P. Van Acker +11 more
doaj +1 more source
Institutional ethics of care in Serbia during the COVID-19 pandemic: A case study on the effects of the lockdown measures on girls and women trafficking survivors [PDF]
Filozofija i Društvo, 2022 Extreme situations such as the COVID-19 pandemic transparently show all the shortcomings of the Serbian system that should, in theory, provide support and protection to citizens in such circumstances.
Ćeriman Jelena +2 more
doaj +1 more source
TLR4 and CD14 trafficking and its influence on LPS-induced pro-inflammatory signaling
Cellular and Molecular Life Sciences, 2020 Toll-like receptor (TLR) 4 belongs to the TLR family of receptors inducing pro-inflammatory responses to invading pathogens. TLR4 is activated by lipopolysaccharide (LPS, endotoxin) of Gram-negative bacteria and sequentially triggers two signaling ...
A. Ciesielska +2 more
semanticscholar +1 more source
BMC Public Health, 2022 Background Effective responses to the worsening drug overdose epidemic require accurate and timely drug overdose surveillance data. The objectives of this paper are to describe the development, functionality, and accuracy of the Suspected Potential ...
Karli R. Hochstatter +5 more
doaj +1 more source
Intracellular trafficking [PDF]
WormBook, 2006 Studies in C. elegans have begun to reveal new components and new mechanisms associated with intracellular membrane traffic in a variety of cell types. The worm benefits from many of the advantages of yeast as a genetically tractable organism for these kinds of studies while offering the unique opportunity to probe how these pathways have been extended
Barth D, Grant, Miyuki, Sato
openaire +2 more sources
Structure of the bacterial flagellar hook cap provides insights into a hook assembly mechanism
Communications Biology, 2021 Matsunami et al determine the structure of the flagellar hook cap from Salmonella enterica by X-ray crystallography. The 3.3 Å resolution structure in combination with mutagenesis analysis provides insights into a putative hook assembly mechanism.
Hideyuki Matsunami +4 more
doaj +1 more source