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Lessons Learned from the Colorado Project to Comprehensively Combat Human Trafficking
Societies, 2023 Countering human trafficking at a statewide level requires a combination of knowledge from lived experience, inter-sector collaborations, and evidence-based tools to measure progress. Since 2010, the nonprofit Laboratory to Combat Human Trafficking (LCHT)
Annie Miller +6 more
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Phospholipase D3 degrades mitochondrial DNA to regulate nucleotide signaling and APP metabolism
Nature Communications, 2023 Phospholipase D3 (PLD3) polymorphisms are linked to late-onset Alzheimer’s disease (LOAD). Being a lysosomal 5’-3’ exonuclease, its neuronal substrates remained unknown as well as how a defective lysosomal nucleotide catabolism connects to AD ...
Zoë P. Van Acker +11 more
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Institutional ethics of care in Serbia during the COVID-19 pandemic: A case study on the effects of the lockdown measures on girls and women trafficking survivors [PDF]
Filozofija i Društvo, 2022 Extreme situations such as the COVID-19 pandemic transparently show all the shortcomings of the Serbian system that should, in theory, provide support and protection to citizens in such circumstances.
Ćeriman Jelena +2 more
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BMC Public Health, 2022 Background Effective responses to the worsening drug overdose epidemic require accurate and timely drug overdose surveillance data. The objectives of this paper are to describe the development, functionality, and accuracy of the Suspected Potential ...
Karli R. Hochstatter +5 more
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Intracellular trafficking [PDF]
WormBook, 2006 Studies in C. elegans have begun to reveal new components and new mechanisms associated with intracellular membrane traffic in a variety of cell types. The worm benefits from many of the advantages of yeast as a genetically tractable organism for these kinds of studies while offering the unique opportunity to probe how these pathways have been extended
Barth D, Grant, Miyuki, Sato
openaire +2 more sources
Deep and fast label-free Dynamic Organellar Mapping
Nature Communications, 2023 The Dynamic Organellar Maps (DOMs) approach combines cell fractionation and shotgun-proteomics for global profiling analysis of protein subcellular localization.
Julia P. Schessner +4 more
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AMA Journal of Ethics, 2018 This first-person narrative describes some of the barriers to caring well for patients at the intersection of human trafficking and substance use disorder. I canvass some of the ethical considerations regarding these patients' autonomy and call for establishing and using evidence-based practice to manage these complex scenarios.
openaire +2 more sources
Endo-lysosomal dysregulations and late-onset Alzheimer’s disease: impact of genetic risk factors
Molecular Neurodegeneration, 2019 Increasing evidence supports that cellular dysregulations in the degradative routes contribute to the initiation and progression of neurodegenerative diseases, including Alzheimer’s disease.
Zoë P. Van Acker +2 more
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Structure of the bacterial flagellar hook cap provides insights into a hook assembly mechanism
Communications Biology, 2021 Matsunami et al determine the structure of the flagellar hook cap from Salmonella enterica by X-ray crystallography. The 3.3 Å resolution structure in combination with mutagenesis analysis provides insights into a putative hook assembly mechanism.
Hideyuki Matsunami +4 more
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VAMP5 and distinct sets of cognate Q-SNAREs mediate exosome release
Cell Structure and Function, 2023 Small extracellular vesicles (sEVs) are largely classified into two types, plasma-membrane derived sEVs and endomembrane-derived sEVs. The latter type (referred to as exosomes herein) is originated from late endosomes or multivesicular bodies (MVBs).
Takahide Matsui +3 more
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