Results 111 to 120 of about 449,298 (313)

Old Spanish Trail Association Collection

open access: yes, 2017
The Old Spanish Trail Association Collection is divided into two series, historic and administrative. The historic papers include: newsletters, correspondence, research, map and trail guides, publications and administrative files.
Old Spanish Trail Association
core   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

Potomac Appalachian Trail Club bulletin

open access: yes, 2016
This 1946 bulletin by the Potomac Appalachian Trail Club includes (pages 104-108) a 1910 letter to Horace Kephart from A.A. Chable who wrote of his “tramping, camping, and mountain climbing” in the Smokies.

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Trail Blazer - Volume 11b, Number 1 [PDF]

open access: yes, 1940
Morehead State Trail Blazer published on July 13, 1940. This issue of the Trail Blazer has a misprinted volume number.https://scholarworks.moreheadstate.edu/trail_blazer/1250/thumbnail ...
Morehead State University. Trail Blazer.
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Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Hikers on the Buckeye Trail

open access: yes, 1963
Photograph of a busload of Buckeye Trail hikers, 1963. The Buckeye Trail winds for about 1,444 miles through Ohio from Lake Erie near Cleveland to the Ohio River near Cincinnati. The Buckeye Trail Association, a non-profit organization created in June of

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Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

Appalachian Trail in North Carolina

open access: yes, 2014
In 1930, the Carolina Appalachian Trail Club was organized for the purpose of completing the western North Carolina segment of the Appalachian Trail. Its home was in Asheville.
Carolina Appalachian Trail Club;
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Trail Blazer - Volume 68, Number 28 [PDF]

open access: yes, 1995
Morehead State Trail Blazer published on May 1, 1996. This issue of the Trail Blazer has a misprinted volume number.https://scholarworks.moreheadstate.edu/trail_blazer/2532/thumbnail ...
Morehead State University. Trail Blazer.
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