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Fungal Apoptosis-Related Proteins

open access: yesMicroorganisms
Programmed cell death (PCD) plays a crucial role in the development and homeostasis maintenance of multicellular organisms. Apoptosis is a form of PCD that prevents pathological development by eliminating damaged or useless cells.
Longjie Li, Chunmei Du
doaj   +3 more sources

Expression of apoptotic protease activating factor-1 in adenoid cystic carcinoma of the salivary glands and its clinicopathological relevance [PDF]

open access: yesVojnosanitetski Pregled, 2022
Background/Aim. Apoptotic protease-activating factor-1 (Apaf-1) is a key molecule in the intrinsic or mitochondrial pathway of apoptosis. Some pathological conditions, such as cancer, stroke, and neurodegenerative diseases, are the result of ...
Dožić Branko   +5 more
doaj   +1 more source

Vitamin B6 Alleviates Lipopolysaccharide-induced Myocardial Injury by Ferroptosis and Apoptosis Regulation

open access: yesFrontiers in Pharmacology, 2021
Vitamin B6 (VitB6) is a water-soluble vitamin and includes pyridoxine, pyridoxal, pyridoxamine, and their phosphorylated forms. In the current study, we demonstrated that VitB6 could improve lipopolysaccharide (LPS)–induced myocardial injury.
Meirong Shan   +5 more
doaj   +1 more source

Cell cycle markers and apoptotic proteins in oral tongue squamous cell carcinoma in young and elderly patients [PDF]

open access: yesBrazilian Oral Research, 2019
The immunoexpression of p16, p53, and Bax in oral tongue squamous cell carcinoma (OTSCC) in young and elderly patients is assessed based on clinical and morphological parameters.
Luan Éverton Galdino BARNABÉ   +4 more
doaj   +1 more source

Apoptosis Regulators Bcl-2 and Caspase-3

open access: yesEncyclopedia, 2022
Apoptosis, programmed cell death, has a central role in developmental biology and in maintaining the equilibrium of renewing tissues. A founding member of the Bcl-2 family of regulatory proteins for apoptosis is Bcl-2, which is encoded by the BCL2 gene ...
Piret Hussar
doaj   +1 more source

Determination of Key Components in the Bombyx mori p53 Apoptosis Regulation Network Using Y2H-Seq

open access: yesInsects, 2023
The apoptosis pathway is highly conserved between invertebrates and mammals. Although genes encoding the classical apoptosis pathway can be found in the silkworm genome, the regulatory pathway and other apoptotic network genes have yet to be confirmed ...
Meixian Wang   +5 more
doaj   +1 more source

Research progress on molecular mechanism of the interaction between autophagy and apoptosis [PDF]

open access: yesJichu yixue yu linchuang, 2021
Autophagy and apoptosis are two different physiological phenomena, however they are closely related in function. This paper introduces the classification and process of autophagy and apoptosis, and discusses the effects of some key regulatory proteins in
ZHANG Yang, SUN Wan-wan, LU Li-dan, FENG Xiao-ling
doaj  

Logical complexity of Bcl-2 family proteins function in the intrinsic apoptosis [PDF]

open access: yesSrpski Arhiv za Celokupno Lekarstvo, 2019
Apoptosis (type of programmed cell death) is an active process of cellular self-destruction in multicellular organisms. It is characterized by distinctive histomorphological, biochemical, and molecular features.
Adamkov Marian
doaj   +1 more source

How Do Hexokinases Inhibit Receptor-Mediated Apoptosis?

open access: yesBiology, 2022
The regulated cell death apoptosis enables redundant or compromised cells in ontogeny and homeostasis to remove themselves receptor-dependent after extrinsic signaling or after internal stress by BCL-2 proteins on the outer mitochondrial membrane (OMM ...
Axel Schoeniger   +2 more
doaj   +1 more source

Expression proteomics predicts loss of RXR-γ during progression of epithelial ovarian cancer. [PDF]

open access: yesPLoS ONE, 2013
The process of cellular transformation involves cascades of molecular changes that are modulated through altered epigenetic, transcription, post-translational and protein regulatory networks.
Rajkumar S Kalra, Sharmila A Bapat
doaj   +1 more source

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