Results 11 to 20 of about 3,365,976 (292)
Non‐apoptotic functions of apoptosis‐regulatory proteins [PDF]
The EMBO Reports, 2012 During the past two decades, apoptotic cell death has been the subject of an intense wave of investigation, leading to the discovery of multiple gene products that govern both its induction and execution. In parallel, it has progressively become evident that most, if not all, proteins that had initially been discovered for their essential role in ...
Lorenzo Galluzzi +3 more
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Frontiers in Pharmacology, 2021 Vitamin B6 (VitB6) is a water-soluble vitamin and includes pyridoxine, pyridoxal, pyridoxamine, and their phosphorylated forms. In the current study, we demonstrated that VitB6 could improve lipopolysaccharide (LPS)–induced myocardial injury.
Meirong Shan +5 more
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Inhibition of apoptosis by the actin‐regulatory protein gelsolin [PDF]
The EMBO Journal, 1997 Gelsolin is an actin-regulatory protein that modulates actin assembly and disassembly, and is believed to regulate cell motility in vivo through modulation of the actin network. In addition to its actin-regulatory function, gelsolin has also been proposed to affect cell growth. Our present experiments have tested the possible involvement of gelsolin in
Ohtsu, Makoto +10 more
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Cell cycle markers and apoptotic proteins in oral tongue squamous cell carcinoma in young and elderly patients [PDF]
Brazilian Oral Research, 2019 The immunoexpression of p16, p53, and Bax in oral tongue squamous cell carcinoma (OTSCC) in young and elderly patients is assessed based on clinical and morphological parameters.
Luan Éverton Galdino BARNABÉ +4 more
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Research progress on molecular mechanism of the interaction between autophagy and apoptosis [PDF]
Jichu yixue yu linchuang, 2021 Autophagy and apoptosis are two different physiological phenomena, however they are closely related in function. This paper introduces the classification and process of autophagy and apoptosis, and discusses the effects of some key regulatory proteins in
ZHANG Yang, SUN Wan-wan, LU Li-dan, FENG Xiao-ling
doaj
Apoptosis Regulators Bcl-2 and Caspase-3
Encyclopedia, 2022 Apoptosis, programmed cell death, has a central role in developmental biology and in maintaining the equilibrium of renewing tissues. A founding member of the Bcl-2 family of regulatory proteins for apoptosis is Bcl-2, which is encoded by the BCL2 gene ...
Piret Hussar
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Determination of Key Components in the Bombyx mori p53 Apoptosis Regulation Network Using Y2H-Seq
Insects, 2023 The apoptosis pathway is highly conserved between invertebrates and mammals. Although genes encoding the classical apoptosis pathway can be found in the silkworm genome, the regulatory pathway and other apoptotic network genes have yet to be confirmed ...
Meixian Wang +5 more
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Logical complexity of Bcl-2 family proteins function in the intrinsic apoptosis [PDF]
Srpski Arhiv za Celokupno Lekarstvo, 2019 Apoptosis (type of programmed cell death) is an active process of cellular self-destruction in multicellular organisms. It is characterized by distinctive histomorphological, biochemical, and molecular features.
Adamkov Marian
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Apoptosis and mitotic slippage following drug intervention in leukaemia cells [PDF]
, 2011 PhDThe response of leukaemia cells to therapeutic agents includes cell cycle arrest and apoptosis. The former response is useful in retarding disease progression, but induction of the latter is essential for disease eradication.
Omar, Najood Amer
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How Do Hexokinases Inhibit Receptor-Mediated Apoptosis?
Biology, 2022 The regulated cell death apoptosis enables redundant or compromised cells in ontogeny and homeostasis to remove themselves receptor-dependent after extrinsic signaling or after internal stress by BCL-2 proteins on the outer mitochondrial membrane (OMM ...
Axel Schoeniger +2 more
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