Results 11 to 20 of about 446,328 (302)

Activation of Cell Cycle Regulatory Proteins in the Apoptosis of Terminally Differentiated Oligodendrocytes

Neurochemical Research, 2004
There is increasing evidence that proteins normally involved in the cell cycle play a role in the regulation of neuronal apoptotic death following various insults. However, it is not clear if the same mechanisms regulate cell death of oligodendrocytes as well.
Strazza M., Luddi A., Brogi A., Carbone M., Riccio M., Santi S., Melli M., Costantino-Ceccarini E.   +7 more
openaire   +7 more sources

Expression of regulatory and executor proteins of apoptosis in odontogenic keratocyst: a systematic review

Medicina Oral Patología Oral y Cirugia Bucal
The odontogenic keratocyst (OKC) corresponds to the third most common odontogenic cyst of the maxillary bones, originating from the dental lamina or its remnants. Apoptosis dysregulation, due to an imbalance between anti-apoptotic and proapoptotic proteins, has been proposed as a promoter for the development and progression of OKC.
Martínez-Flores, René, Muñoz-Orrego, Matías, Marín-Márquez, Constanza, Schuch, Lauren F., Silveira, Felipe Martins, Bologna Molina, Ronell, Niklander, Sven   +6 more
openaire   +4 more sources

Expression of Cell Cycle and Apoptosis Regulatory Proteins and Telomerase in Melanocitic Lesions

Collegium antropologicum, 2007
To gain insight into the role and association of cell cycle and apoptosis regulatory proteins and telomerase activity in the course of progression of melanocitic lesions we have examined immunohistochemicaly, expression and the distribution of p53, bcl-2, Ki-67 and telomerase in 25 samples of common and dysplastic nevi, and 45 samples of primary ...
Batinac, Tanja, Hadžisejdić, Ita, Brumini, Gordana, Ružić, Alen, Vojniković, Božidar, Zamolo, Gordana   +5 more
openaire   +6 more sources

Effects of Periostracum Cicadae on Cytokines and Apoptosis Regulatory Proteins in an IgA Nephropathy Rat Model. [PDF]

Int J Mol Sci, 2018
Periostracum cicadae, the cast-off shell of the cicada Cryptotympana pustulata Fabricius, is used in traditional Chinese medicine for its diaphoretic, anticonvulsive, sedative, antipyretic, and antiallergic effects. However, the exact pathogenesis of immunoglobulin A nephropathy (IgAN) remains unclear, thereby hindering investigations to identify novel
Yang L, Wang Y, Nuerbiye A, Cheng P, Wang JH, Kasimu R, Li H.   +6 more
europepmc   +4 more sources

Non‐apoptotic functions of apoptosis‐regulatory proteins [PDF]

EMBO reports, 2012
During the past two decades, apoptotic cell death has been the subject of an intense wave of investigation, leading to the discovery of multiple gene products that govern both its induction and execution. In parallel, it has progressively become evident that most, if not all, proteins that had initially been discovered for their ...
Lorenzo Galluzzi, Oliver Kepp, Christina Trojel-Hansen, Guido Kroemer   +3 more
openaire   +2 more sources

Inhibition of apoptosis by the actin-regulatory protein gelsolin [PDF]

The EMBO Journal, 1997
Gelsolin is an actin-regulatory protein that modulates actin assembly and disassembly, and is believed to regulate cell motility in vivo through modulation of the actin network. In addition to its actin-regulatory function, gelsolin has also been proposed to affect cell growth. Our present experiments have tested the possible involvement of gelsolin in
Ohtsu, Makoto, Sakai, Norio, Fujita, Hisakazu, Kashiwagi, Motoi, Gasa, Shinsei, Shimizu, Shigeomi, Eguchi, Yutaka, Tsujimoto, Yoshihide, Sakiyama, Yukio, Kobayashi, Kunihiko, Kuzumaki, Noboru   +10 more
openaire   +2 more sources

Proliferation, apoptosis and their regulatory protein expression in colorectal adenomas and serrated lesions

PLOS ONE, 2021
Background Adenomas and serrated lesions represent heterogeneous sets of early precursors in the colorectum with varying malignant potential. They are often distinguished by their histopathologic differences, but little is known about potential differences in regulation of epithelial proliferation and apoptosis.
Jane C. Figueiredo, Michael N. Passarelli, Wei Wei, Dennis J. Ahnen, Jeffrey S. Morris, Lynda Corley, Trupti Mehta, Angela N. Bartley, Gail McKeown-Eyssen, Robert S. Bresalier, Elizabeth L. Barry, Ajay Goel, Goretti Hernandez Mesa, Stanley R. Hamilton, John A. Baron   +14 more
openaire   +5 more sources

Role of Cell Cycle Regulatory Proteins in Cerebellar Granule Neuron Apoptosis [PDF]

The Journal of Neuroscience, 1999
Cerebellar granule neurons (CGNs) undergo apoptosis when deprived of depolarizing concentrations of KCl, but the underlying molecular mechanisms are not yet clear. Although caspases have been postulated to be involved in CGN cell death, inhibitors of caspases failed to prevent apoptosis under our culture conditions, suggesting an involvement of other ...
J, Padmanabhan, D S, Park, L A, Greene, M L, Shelanski   +3 more
openaire   +2 more sources

Exposure to the complement C5b-9 complex sensitizes 661W photoreceptor cells to both apoptosis and necroptosis. [PDF]

, 2015
The loss of photoreceptors is the defining characteristic of many retinal degenerative diseases, but the mechanisms that regulate photoreceptor cell death are not fully understood.
Dimitrios Stampoulis, M. Francesca Cordeiro, Williams, JA, Jennifer A. E. Williams, Stampoulis, D, Li Guo, Shi, H, Guo, L, Moss, SE, Francesca Cordeiro, M, Stephen E. Moss, Hui Shi   +11 more
core   +1 more source

Induction of Noxa-mediated apoptosis by modified vaccinia virus Ankara depends on viral recognition by cytosolic helicases, leading to IRF-3/IFN-β-dependent induction of pro-apoptotic Noxa. [PDF]

, 2011
Viral infection is a stimulus for apoptosis, and in order to sustain viral replication many viruses are known to carry genes encoding apoptosis inhibitors. F1L, encoded by the orthopoxvirus modified vaccinia virus Ankara (MVA) has a Bcl-2-like structure.
Potthoff, Stephanie, Häcker Georg, Sutter Gerd, Kastenmüller, Wolfgang, Drexler, I., Eitz Ferrer Pedro, Ludwig, H., Gasteiger Georg, Sutter, G., Gasteiger, Georg, Holger Ludwig, Stefan A Paschen, Stefan A. Paschen, Stephanie Potthoff, Potthoff, S., Susanne Kirschnek, Kirschnek, Susanne, Kastenmüller Wolfgang, Pedro Eitz Ferrer, Kirschnek, S., Häcker, Georg, Potthoff Stephanie, Villunger Andreas, Georg Gasteiger, Villunger, A., Ludwig, Holger, Georg Häcker, Drexler Ingo, Wolfgang Kastenmüller, Villunger, Andreas, Ingo Drexler, Gasteiger, G., Paschen, Stefan A., Sutter, Gerd, Häcker, G., Eitz Ferrer, Pedro, Kastenmüller, W., Kirschnek Susanne, Paschen Stefan A., Gerd Sutter, Ludwig Holger, Paschen, S.A., Andreas Villunger, Eitz Ferrer, P., Drexler, Ingo   +44 more
core   +1 more source