Results 1 to 10 of about 358 (70)
FKBP51 Affects TNF-Related Apoptosis Inducing Ligand Response in Melanoma
Frontiers in Cell and Developmental Biology, 2021 Melanoma is one of the most immunogenic tumors and has the highest potential to elicit specific adaptive antitumor immune responses. Immune cells induce apoptosis of cancer cells either by soluble factors or by triggering cell-death pathways.
Martina Tufano +5 more
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Biomédica: revista del Instituto Nacional de Salud, 2022 Introduction: More than half of all worldwide deaths and disabilities were caused by stroke. Large artery atherosclerosis is identified as a high etiological risk factor because it accounts for 20% of ischemic stroke.
Ozge Altintas Kadirhan +2 more
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TRAIL and its receptors in cardiac diseases
Frontiers in Physiology, 2023 Cardiovascular disease is a leading cause of death worldwide. Loss of cardiomyocytes that occurs during many types of damage to the heart such as ischemic injury and stress caused by pressure overload, diminishes cardiac function due to their limited ...
Laurel A. Grisanti
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Behind the Adaptive and Resistance Mechanisms of Cancer Stem Cells to TRAIL
Pharmaceutics, 2021 Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL), also known as Apo-2 ligand (Apo2L), is a member of the TNF cytokine superfamily. TRAIL has been widely studied as a novel strategy for tumor elimination, as cancer cells overexpress ...
Adriana G. Quiroz-Reyes +5 more
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Unspecific CTL Killing Is Enhanced by High Glucose via TNF-Related Apoptosis-Inducing Ligand
Frontiers in Immunology, 2022 TNF-related apoptosis inducing ligand (TRAIL) is expressed on cytotoxic T lymphocytes (CTLs) and TRAIL is linked to progression of diabetes. However, the impact of high glucose on TRAIL expression and its related killing function in CTLs still remains ...
Wenjuan Yang +25 more
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Prognostic value of TNF-related apoptosis inducing ligand (TRAIL) in acute coronary syndrome patients. [PDF]
PLoS ONE, 2013 BACKGROUND: Apoptosis plays an important role in the development of heart failure. The aim of the prospectively designed study was to assess whether the concentration of apoptotic markers apoptosis-stimulating fragment (Fas, CD95/APO-1) and tumor ...
Pavel Osmancik +4 more
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The Egyptian Journal of Internal Medicine, 2012 IntroductionTumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is a tumor necrosis factor (TNF) family member capable of inducing apoptosis in many cell types.
Mustafa Abdelaziz Mustafa +2 more
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Targeting Ameloblatoma into Apoptosis
Indonesian Biomedical Journal, 2018 BACKGROUND: Generally ameloblastoma is a locally aggressive, slow growing, non-metastatic epithelial odontogenic benign tumor. However, rarely some ameloblastoma can metastasize in spite of a benign histologic appearance.
Ferry Sandra
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Evidence for a Proangiogenic Activity of TNF-Related Apoptosis-Inducing Ligand
Neoplasia: An International Journal for Oncology Research, 2004 Starting from the observation that tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)/ Apo-2L protein is expressed in both malignant and inflammatory cells in some highly vascularized soft tissue sarcomas, the angiogenic potential of TRAIL ...
Paola Secchiero +7 more
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BMC Cancer, 2023 Background Aponermin, a circularly permuted tumor necrosis factor-related apoptosis-inducing ligand, is a potential death receptor 4/5-targeted antitumour candidate.
Zhongjun Xia +53 more
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