Results 21 to 30 of about 10,050,273 (238)

TNF–related apoptosis-inducing ligand (TRAIL) and erythropoiesis: a role for PKCe

European Journal of Histochemistry, 2009
The regulation of the hematopoietic stem cell pool size and the processes of cell differentiation along the hematopoietic lineages involve apoptosis. Among the different factors with a recognized activity on blood progenitor cells, TRAIL - a member of ...
M Vitale, G Gobbi, P Mirandola, C Ponti, I Sponzilli, L Rinaldi, FA Manzoli   +6 more
doaj   +1 more source

TNF-related apoptosis-inducing ligand level in Alzheimer’s disease

Neurological Sciences, 2009
In the present study, we determined the significance of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) in Alzheimer's disease (AD). We characterized the expression of TRAIL protein in the cerebrospinal fluid (CSF) and serum with ELISA and TRAIL mRNA in the peripheral blood mononuclear cells (PBMCs) with real-time PCR in 22 patients ...
Genc, Sermin, Egrilmez, Mehtap Yuksel, Yaka, Erdem, Cavdar, Zahide, Iyilikci, Leyla, Yener, Gorsev, Genc, Kursad   +6 more
openaire   +4 more sources

Molecular cloning, expression analysis and assignment of the porcine tumor necrosis factor superfamily member 10 gene (TNFSF10) to SSC13q34 -> q36 by fluorescence in situ hybridization and radiation hybrid mapping [PDF]

, 2005
We have cloned the complete coding region of the porcine TNFSF10 gene. The porcine TNFSF10 cDNA has an ORF of 870 nucleotides and shares 85 % identity with human TNFSF10, and 75% and 72% identity with rat and mouse Tnfsf10 coding sequences, respectively.
Kemter, E., Kemter, E, Leeb, T., Kuiper, H., Klose, R., Boelhauve, M., Kuiper, H, Philipp, U., Philipp, U, Wolf, E, Distl, O., Wolf, E., Klose, R, Leeb, Tosso, Distl, O, Boelhauve, M   +15 more
core   +2 more sources

Correlation of Serum Levels of Interleukine-16, CCL27, Tumor Necrosis Factor-related Apoptosis-inducing Ligand, and B-cell Activating Factor with Multiple Sclerosis Severity

Iranian Journal of Allergy, Asthma and Immunology, 2022
The pathogenic roles of Interleukine-16 (IL-16), CCL27, tumor necrosis factor-related apoptosis-inducing ligand (TRAIL), and B-cell activating factor (BAFF) has been shown in some autoimmune and inflammatory diseases.
Ebrahim Kouchaki, Hossein Akbari, Fatemeh Mahmoudi, Mahdi Salehi, Effat Naimi, Hassan Nikoueinejad   +5 more
doaj   +1 more source

Microsatellite instability, KRAS mutations and cellular distribution of TRAIL-receptors in early stage colorectal cancer. [PDF]

, 2012
Thus, we evaluated the immunofluorescence pattern of TRAIL-receptors and E-cadherin to assess the fraction of membrane-bound TRAIL-receptors in 231 selected patients with early-stage CRC undergoing surgical treatment only.
Göke, Burkhard, Thomas Kirchner (109827), Rene Jackstadt, Gallmeier, Eike, Thomas Kirchner, Gerbes, Alexander L., Kriegl, Lydia, Eike Gallmeier, Jackstadt, Rene, Alexander L Gerbes, Burkhard Göke (109829), De Toni, Enrico N., Eike Gallmeier (109823), Enrico N De Toni, Burkhard Göke, Horst, David, Andreas Jung, Rene Jackstadt (109815), David Horst, Jung, Andreas, Antonia Rizzani (109811), Heiko Hermeking (109819), Alexander L. Gerbes (109825), Kirchner, Thomas, Andreas Jung (109804), David Horst (109808), Enrico N. De Toni (109830), Lydia Kriegl, Rizzani, Antonia, Hermeking, Heiko, Heiko Hermeking, Lydia Kriegl (109801), Antonia Rizzani   +32 more
core   +2 more sources

Follow-up Analysis of Serum TNF-Related Apoptosis-Inducing Ligand Protein and mRNA Expression in Peripheral Blood Mononuclear Cells from Patients with Ischemic Stroke

Frontiers in Neurology, 2018
Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL), which is TNF receptor superfamily member, contributes to several diseases pathogenesis.
Kemal Ugur Tufekci, Kemal Ugur Tufekci, Ufuk Vurgun, Ufuk Vurgun, Onur Yigitaslan, Pembe Keskinoglu, Erdem Yaka, Kursad Kutluk, Sermin Genc, Sermin Genc   +9 more
doaj   +1 more source

Antiproliferative and Apoptotic Effect of Curcumin and TRAIL (TNF Related Apoptosis inducing Ligand) in Chronic Myeloid Leukaemic Cells [PDF]

Journal of Clinical and Diagnostic Research, 2016
Introduction: Curcumin, traditionally utilized as a flavouring zest as a part of Indian cooking, has been accounted to decrease the proliferation potential of most cancer cells.
Bushra Iqbal, Archna Ghildiyal, Sahabjada, Shraddha Singh, Mohd. Arshad, Abbas Ali Mahdi, Sunita Tiwari   +6 more
doaj   +1 more source

Necroptosis of Lung Epithelial Cells Triggered by Ricin Toxin and Bystander Inflammation

Cellular Physiology and Biochemistry, 2023
Background/Aims: The ribosome-inactivating proteins include the biothreat agent, ricin toxin (RT). When inhaled, RT causes near complete destruction of the lung epithelium coincident with a proinflammatory response that includes TNF family cytokines ...
LaRocca
doaj   +1 more source

TNF‐related apoptosis‐inducing ligand suppresses PRDX4 expression

FEBS Letters, 2009
TNF‐related apoptosis‐inducing ligand (TRAIL) is currently considered a promising target for developing anti‐cancer therapies. Accumulating evidences have now shown that oxidative stress is involved in the TRAIL‐mediated cell death. The peroxiredoxins (PRDXs) are a ubiquitous family of proteins involved in protection against oxidative stress through ...
Wang, Hua-Qin, Du, Zhen-Xian, Liu, Bao-Qin, Gao, Yan-Yan, Meng, Xin, Guan, Yifu, Zhang, Hai-Yan   +6 more
openaire   +2 more sources

CD40 ligand induced cytotoxicity in carcinoma cells is enhanced by inhibition of metalloproteinase cleavage and delivery via a conditionally-replicating adenovirus [PDF]

, 2010
Background CD40 and its ligand (CD40L) play a critical role in co-ordinating immune responses. CD40 is also expressed in lymphoid malignancies and a number of carcinomas. In carcinoma cells the physiological outcome of CD40 ligation depends on the level
Young Lawrence S, Elmetwali, Taha, Mcneish, I., Searle Peter F, Young, Lawrence, Searle, PF, Palmer Daniel H, McNeish, I, Young, Lawrence S., Palmer, D.H., McNeish, Iain, Peter F Searle, Lawrence S Young, Elmetwali, T., Searle, P.F., Elmetwali Taha, Iain McNeish, Young, LS, McNeish Iain, Palmer, Daniel H., Palmer, DH, Searle, Peter F., Daniel H Palmer, Young, L.S., Taha Elmetwali, Palmer, Daniel, Searle, Peter, Elmetwali, T   +27 more
core   +1 more source