Results 131 to 140 of about 449,298 (313)

Trail Blazer - Volume 23b, Number 1 [PDF]

open access: yes, 1952
Morehead State Trail Blazer published on September 29, 1953. This issue of the Trail Blazer has a misprinted volume number.https://scholarworks.moreheadstate.edu/trail_blazer/1502/thumbnail ...
Morehead State University. Trail Blazer.
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SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

Souvenir postcard of Trail

open access: yes, 1951
Taken from West Trail looking across the Columbia River towards East ...

core  

Trail Blazer - Volume 48, Number 4 [PDF]

open access: yes, 1975
Morehead State Trail Blazer published on September 2, 1975. This issue of the Trail Blazer has a misprinted volume number, leading to a false gap in this database.https://scholarworks.moreheadstate.edu/trail_blazer/1944/thumbnail ...
Morehead State University. Trail Blazer.
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Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

open access: yesMolecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim   +11 more
wiley   +1 more source

Buckeye Trail Dedication at Mogadore Reservoir

open access: yes, 1970
State Senators Ralph Regula and Harry Armstrong painting a "golden blaze" on a post at a dedication ceremony for the Buckeye Trail at Mogadore Reservoir in Portage County, Ohio, October 10, 1970.
Akron Beacon Journal (Publisher)
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Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

Use of a Community Trail Among New and Habitual Exercisers: A Preliminary Assessment

open access: yesPreventing Chronic Disease, 2004
Introduction We evaluated physical activity patterns and trail use among new and habitually active exercisers using onsite trail interviews. Methods Using a cross-sectional study design, 414 adults who accessed two new trails that bisect a rural ...
Paul M. Gordon   +2 more
doaj  

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

open access: yesFEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta   +7 more
wiley   +1 more source

Video Promocional Revista Ultra Trail

open access: yes, 2014
Revista Ultra Trail Colombia no posee los derechos de las imagenes aqui expuestas.
Ultra Trail Magazine
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