Results 181 to 190 of about 449,298 (313)

TRAIL splice variant TRAILshort disrupts T cell receptor signaling and promotes immune tolerance in vivo. [PDF]

J Clin Invest
Jalali S, Natesampillai S, Nie Z, Zhang Y, Can I, Chandrasekar AP, Hameister BM, Correia C, Zhao TV, Mun DG, Garcia-Rivera E, Matson R, Krogman A, Maynes MA, Batchelor R, Monie DD, Li H, Behfar A, Kenderian SS, Pandey A, Ansell SM, Taner T, Weyand C, Billadeau DD, Badley AD.   +24 more
europepmc   +1 more source

Trail City Council, 1969 - M.M. Morrison, Trail councillor

, 1969
Following amalgamation of Trail and ...

core  

Cell surface CD11c as a neutrophil aging marker molecule

FEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki, Fahd Alhamdan, Erik Malm, Marie Bermudez, Samuel Y. Kim, Koichi Yuki   +5 more
wiley   +1 more source

Analytical model of route-based pricing for time dependent traffic assignment. (online)

, 2012
TRAIL, Kern, Walter, Still, Georg J., van Berkum, Eric C., Ohazulike, Anthony   +4 more
core   +1 more source

Stem Cell-Delivered Cytosine Deaminase/5-Fluorocytosine and TRAIL Gene Therapy for Castration-Resistant Prostate Cancer: Translational Synthesis and First-in-Human Trial Concept. [PDF]

Int J Mol Sci
Kim JH, Song M, Lee K, Lee SH, Song YS.
europepmc   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Synergistic lethality of combination treatment with Trop2-directed antibody-drug conjugate sacituzumab govitecan and TRAIL agonists in triple negative breast cancer. [PDF]

Breast Cancer Res
Addissie YA, Greer YE, Nair J, Lipkowitz S.   +3 more
europepmc   +1 more source

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

FEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen, Duc Trung Nguyen, Minyoung Cho, Jihun Kim, Soyeon In, Thai Uy Nguyen, Sunghoon Hurh, Beom Jin Park, Jong‐Ik Hwang   +8 more
wiley   +1 more source

MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation

FEBS Open Bio, EarlyView.
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima, Kotone Watanabe, Grigorii Sultanakhmetov, Aoi Fukuchi, Keiya Ito, Sawako Shimizu, Taro Saito, Akiko Asada, Kanae Ando   +8 more
wiley   +1 more source

Inhibition of UBE2N enhances TRAIL-mediated apoptosis through upregulation of DR5 in cancer cells. [PDF]

Int J Med Sci
Jeong YJ, Woo SM, Seo SU, Song SR, Kwon TK.   +4 more
europepmc   +1 more source