Results 71 to 80 of about 449,298 (313)
Old Oregon Trail from the Missouri to the Pacific
, 1943 Relief shown pictoriallyShows the Old Oregon Trail, Mormon Trail, Lewis and Clark's route, Applegate Trail, Naches Pass Trail, Barlow Road, and Fremont's routeIncludes pictorial representations of landmarks, animals, and peopleThis archived document is ...
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FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Arctic ScienceAs part of an Inuit-led initiative, a collaborative research project combined scientific methods and Inuit knowledge to design an environmentally friendly and climate change-resilient access route from the community of Kugluktuk to Kugluk Territorial ...
Michel Allard +7 more
doaj +1 more source
Targeting of keloid with TRAIL and TRAIL-R2/DR5
Journal of Dermatological Treatment, 2020 Keloid is a common and frequently-occurring disease in plastic surgery, and its ugly appearance and itching symptoms bring mental and life pain to patients. However, the clinical treatment of keloid, such as drug injection treatment, surgical resection, cryotherapy, laser treatment and other therapeutic effects are poor.
Pengfei, Sun +3 more
openaire +2 more sources
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
, 1981 "March 1981."; Cover title of accompanying text: Comprehensive plan.; Spine title of accompanying text: Appalachian Trail comprehensive plan.; "Source Data: Map base is Geological Survey 1:2,500,000 scale map, dated 1972."; Accompanied by text ...
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Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Clinical EpigeneticsBackground Human aging and white blood cell (WBC) count are complex traits influenced by multiple genetic factors. Predictors of chronological age have been developed using epigenetic clocks.
Manli Sun +8 more
doaj +1 more source
REM: International Engineering JournalSoil provides important support for anthropogenic activities, and earthen trails, which have always been present in the natural landscape, are routes of access to various tourist attractions. In recent decades, trails have been widely used as a method of
Ricardo Eustáquio Fonseca Filho +3 more
doaj +1 more source
PASOS Revista de Turismo y Patrimonio Cultural, 2017 El running se ha convertido en poco tiempo en un deporte de masas, generando todo un negocio a su alrededor y un impacto económico importante en aquellas localidades que albergan este tipo de eventos.
FEDERICO SOLER VAYÁ +1 more
doaj +1 more source