Results 51 to 60 of about 1,435,170 (249)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
System Identification for Nonlinear Control Using Neural Networks [PDF]
, 1990 An approach to incorporating artificial neural networks in nonlinear, adaptive control systems is described. The controller contains three principal elements: a nonlinear inverse dynamic control law whose coefficients depend on a comprehensive model of ...
Linse, Dennis J., Stengel, Robert F.
core +1 more source
Current status analysis and countermeasure exploration for train communication network security
机车电传动, 2023 With the in-depth application of Ethernet technology in the train networked control system, the train communication network is facing increasing cybersecurity challenges.
ZOU Zhirong +3 more
doaj
FEBS Letters, EarlyView.Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
Research on High-speed Train Control System Based on Ethernet
机车电传动, 2019 Because of the unique advantages of Ethernet in improving the efficiency of train maintenance, reducing maintenance costs and promoting train intellectualization, building intelligent control system based on Ethernet will be the development trend of ...
Yan XIONG, He HUANG, Siyuan LI, Qing XU
doaj
Study on Application Solution of Moving Block in Heavy Haul Railway
机车电传动, 2020 Based on the analysis of existing blocking system and train control mode of heavy haul railway, combined with current application of moving block, the key points and difficult problems of heavy haul railway adopting moving block were analyzed.
Feng LI
doaj
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
CASSL: Curriculum Accelerated Self-Supervised Learning
, 2018 Recent self-supervised learning approaches focus on using a few thousand data points to learn policies for high-level, low-dimensional action spaces.
Gandhi, Dhiraj +3 more
core +1 more source
Research on the Solution of Train-trackside CooperativeShortening Movement Authority
Kongzhi Yu Xinxi Jishu, 2020 In railway operations, when an opened route needs to be closed occasionally, the approach locking function of interlocking is needed to avoid the trip risk of a train.
LI Qihe
doaj
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source