Results 41 to 50 of about 1,069 (249)
Energy-Saving Train Regulation for Metro Lines Using Distributed Model Predictive Control
Energies, 2020 Due to environmental concerns, the energy-saving train regulation is necessary for urban metro transportation, which can improve the service quality and energy efficiency of metro lines.
Fei Shang, Jingyuan Zhan, Yangzhou Chen
doaj +1 more source
Journal of Advanced Transportation, 2022 This paper describes an optimization model for an irregular train schedule. The aim is to optimize both the maximum train loading rate and the average deviation of departure intervals under time-varying passenger transport demand for an urban rail ...
Hai Zhang, Shaoquan Ni
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FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Operational Challenges of the Bangkok Airport Rail Link
Urban Rail Transit, 2020 The airport rail link (ARL) was launched in 2010 as a premium rail transit service between the inner city of Bangkok and the airport. In 2014, the express service was canceled due to its unpopularity and transformed into the commuter service.
Waressara Weerawat +2 more
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Integrated energy‐efficient optimization for urban rail transit timetable
IET Intelligent Transport Systems, 2023 The energy‐efficient optimization of the train timetable should be carried out on the basis of meeting passenger demand and determining the train operation plan.
Lianbo Deng +4 more
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Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source