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The traits of “trait ecologists”: An analysis of the use of trait and functional trait terminology [PDF]
Trait and functional trait approaches have revolutionized ecology improving our understanding of community assembly, species coexistence, and biodiversity loss. Focusing on traits promotes comparability across spatial and organizational scales, but terms
Samantha K. Dawson +9 more
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Detecting natural selection in trait-trait coevolution [PDF]
ABSTRACTNo phenotypic trait evolves independently of all other traits, but the cause of trait-trait coevolution is poorly understood. While the coevolution could arise simply from pleiotropic mutations that simultaneously affect the traits concerned, it could also result from multivariate natural selection favoring certain trait relationships.
Daohan Jiang, Jianzhi Zhang
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Rare variant aggregation in 148,508 exomes identifies genes associated with proxy dementia
Proxy phenotypes allow for the utilization of genetic data from large population cohorts to analyze late-onset diseases by using parental diagnoses as a proxy for genetic disease risk. Proxy phenotypes based on parental diagnosis status have been used in
Douglas P. Wightman +4 more
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A Correction to this paper has been published: https://doi.org/10.1038/s41398-021-01334 ...
Josefin Werme +3 more
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Flattening TraitsTraits are fine-grained components that can be used to compose classes, while avoiding many of the problems of multiple inheritance and mixin-based approaches. Since most implementations of traits have focused on dynamically-typed languages, the question naturally arises, how can one best introduce traits to statically-typed languages,
Nierstrasz, Oscar +2 more
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A genome-wide association study on MRI cerebellar volume in the UK Biobank cohort identifies 30 loci with genome-wide significance that might be relevant to brain structure and cognitive function.
Elleke Tissink +8 more
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Gene-environment interactions (GxE) are often suggested to play an important role in the aetiology of psychiatric phenotypes, yet so far, only a handful of genome-wide environment interaction studies (GWEIS) of psychiatric phenotypes have been conducted.
Josefin Werme +3 more
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Genome-wide meta-analysis of brain volume identifies genomic loci and genes shared with intelligence
Brain volume and intelligence have been previously found to have shared genetic etiology, but the specific common genetic signals have not been identified.
Philip R. Jansen +8 more
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Author Correction: Genetic mapping of cell type specificity for complex traits
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Kyoko Watanabe +4 more
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Genome editing in maize directed by CRISPR–Cas9 ribonucleoprotein complexes
Genome editing in plants typically requires the expression of Cas9 and guide RNA from stably transformed plasmid DNA. Here, the authors show that successful editing can be achieved after delivery of the Cas9-guide RNA complex as a ribonucleoprotein to ...
Sergei Svitashev +4 more
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