Results 1 to 10 of about 624,979 (323)
Rare variant aggregation in 148,508 exomes identifies genes associated with proxy dementia
Scientific Reports, 2023 Proxy phenotypes allow for the utilization of genetic data from large population cohorts to analyze late-onset diseases by using parental diagnoses as a proxy for genetic disease risk. Proxy phenotypes based on parental diagnosis status have been used in
Douglas P. Wightman +4 more
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Translational Psychiatry, 2021 Gene-environment interactions (GxE) are often suggested to play an important role in the aetiology of psychiatric phenotypes, yet so far, only a handful of genome-wide environment interaction studies (GWEIS) of psychiatric phenotypes have been conducted.
Josefin Werme +3 more
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Communications Biology, 2022 A genome-wide association study on MRI cerebellar volume in the UK Biobank cohort identifies 30 loci with genome-wide significance that might be relevant to brain structure and cognitive function.
Elleke Tissink +8 more
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Translational Psychiatry, 2021 A Correction to this paper has been published: https://doi.org/10.1038/s41398-021-01334 ...
Josefin Werme +3 more
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On the Fourier transform of a quantitative trait: Implications for compressive sensing [PDF]
Journal of Theoretical Biology, Vol. 540, Year 2022, Article ID
110985, ISSN 0022-5193, 2021 This paper explores the genotype-phenotype relationship. It outlines conditions under which the dependence of a quantitative trait on the genome might be predictable, based on measurement of a limited subset of genotypes. It uses the theory of real-valued Boolean functions in a systematic way to translate trait data into the Fourier domain.
arxiv +1 more source
Prompt- and Trait Relation-aware Cross-prompt Essay Trait Scoring [PDF]
, 2023 Automated essay scoring (AES) aims to score essays written for a given prompt, which defines the writing topic. Most existing AES systems assume to grade essays of the same prompt as used in training and assign only a holistic score. However, such settings conflict with real-education situations; pre-graded essays for a particular prompt are lacking ...
arxiv +1 more source
Genome-wide meta-analysis of brain volume identifies genomic loci and genes shared with intelligence
Nature Communications, 2020 Brain volume and intelligence have been previously found to have shared genetic etiology, but the specific common genetic signals have not been identified.
Philip R. Jansen +8 more
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Genome editing in maize directed by CRISPR–Cas9 ribonucleoprotein complexes
Nature Communications, 2016 Genome editing in plants typically requires the expression of Cas9 and guide RNA from stably transformed plasmid DNA. Here, the authors show that successful editing can be achieved after delivery of the Cas9-guide RNA complex as a ribonucleoprotein to ...
Sergei Svitashev +4 more
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Author Correction: Genetic mapping of cell type specificity for complex traits
Nature Communications, 2020 An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Kyoko Watanabe +4 more
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MycoNews 2022: editorial, news, reports, awards, personalia, and book news
IMA Fungus, 2023 This fourth annual edition of MycoNews starts with an editorial asking if mycology is approaching a tipping point, and note of the journal’s 2021 Impact Factor almost doubling from 2020. Updated information and new speakers for IMC12 in 2024 is presented.
David L. Hawksworth
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