Results 1 to 10 of about 1,773,362 (339)

Genome-wide association study of cerebellar volume provides insights into heritable mechanisms underlying brain development and mental health

Communications Biology, 2022
A genome-wide association study on MRI cerebellar volume in the UK Biobank cohort identifies 30 loci with genome-wide significance that might be relevant to brain structure and cognitive function.
Elleke Tissink, Siemon C. de Lange, Jeanne E. Savage, Douglas P. Wightman, Christiaan A. de Leeuw, Kristen M. Kelly, Mats Nagel, Martijn P. van den Heuvel, Danielle Posthuma   +8 more
doaj   +1 more source

Rare variant aggregation in 148,508 exomes identifies genes associated with proxy dementia

Scientific Reports, 2023
Proxy phenotypes allow for the utilization of genetic data from large population cohorts to analyze late-onset diseases by using parental diagnoses as a proxy for genetic disease risk. Proxy phenotypes based on parental diagnosis status have been used in
Douglas P. Wightman, Jeanne E. Savage, Christiaan A. de Leeuw, Iris E. Jansen, Danielle Posthuma   +4 more
doaj   +1 more source

Correction to: Genome-wide gene-environment interactions in neuroticism: an exploratory study across 25 environments

Translational Psychiatry, 2021
A Correction to this paper has been published: https://doi.org/10.1038/s41398-021-01334 ...
Josefin Werme, Sophie van der Sluis, Danielle Posthuma, Christiaan A. de Leeuw   +3 more
doaj   +1 more source

Genome-wide gene-environment interactions in neuroticism: an exploratory study across 25 environments

Translational Psychiatry, 2021
Gene-environment interactions (GxE) are often suggested to play an important role in the aetiology of psychiatric phenotypes, yet so far, only a handful of genome-wide environment interaction studies (GWEIS) of psychiatric phenotypes have been conducted.
Josefin Werme, Sophie van der Sluis, Danielle Posthuma, Christiaan A. de Leeuw   +3 more
doaj   +1 more source

Genome-wide meta-analysis of brain volume identifies genomic loci and genes shared with intelligence

Nature Communications, 2020
Brain volume and intelligence have been previously found to have shared genetic etiology, but the specific common genetic signals have not been identified.
Philip R. Jansen, Mats Nagel, Kyoko Watanabe, Yongbin Wei, Jeanne E. Savage, Christiaan A. de Leeuw, Martijn P. van den Heuvel, Sophie van der Sluis, Danielle Posthuma   +8 more
doaj   +1 more source

Open Science principles for accelerating trait-based science across the Tree of Life. [PDF]

, 2020
Synthesizing trait observations and knowledge across the Tree of Life remains a grand challenge for biodiversity science. Species traits are widely used in ecological and evolutionary science, and new data and methods have proliferated rapidly.
Adams, Vanessa M, Alroy, John, Andrew, Samuel C, Ankenbrand, Markus J, Balk, Meghan A, Bland, Lucie M, Boyle, Brad L, Bravo-Avila, Catherine H, Brennan, Ian, Carthey, Alexandra JR, Catullo, Renee, Cavazos, Brittany R, Chown, Steven L, Conde, Dalia A, Enquist, Brian J, Fadrique, Belen, Falster, Daniel S, Feng, Xiao, Gallagher, Rachael V, Gibb, Heloise, Halbritter, Aud H, Hammock, Jennifer, Hogan, J Aaron, Holewa, Hamish, Hope, Michael, Iversen, Colleen M, Jochum, Malte, Kattge, Jens, Kearney, Michael, Keller, Alexander, Mabee, Paula, Madin, Joshua S, Maitner, Brian S, Manning, Peter, McCormack, Luke, Michaletz, Sean T, Park, Daniel S, Pearse, William D, Penone, Caterina, Perez, Timothy M, Pineda-Munoz, Silvia, Poelen, Jorrit H, Ray, Courtenay A, Rossetto, Maurizio, Salguero-Gómez, Roberto, Sauquet, Hervé, Schneider, Florian D, Sparrow, Benjamin, Spasojevic, Marko J, Telford, Richard J, Tobias, Joseph A, Vandvik, Vigdis, Violle, Cyrille, Walls, Ramona, Weiss, Katherine CB, Westoby, Mark, Wright, Ian J   +56 more
core   +4 more sources

Genetic distance predicts trait differentiation at the subpopulation but not the individual level in eelgrass, Zostera marina. [PDF]

, 2018
Ecological studies often assume that genetically similar individuals will be more similar in phenotypic traits, such that genetic diversity can serve as a proxy for trait diversity.
Corre V., Harvey P. H., Hughes A. R., Koroleff F., Platt T., R Core Team, Williams S. L.   +6 more
core   +2 more sources

\u201cGive, but Give until It Hurts\u201d: The Modulatory Role of Trait Emotional Intelligence on the Motivation to Help [PDF]

, 2015
Two studies investigated the effect of trait Emotional Intelligence (trait EI) on people\u2019s moti- vation to help. In Study 1, we developed a new computer-based paradigm that tested partic- ipants\u2019 motivation to help by measuring their ...
A Furnham, Andrea Pittarello, CD Batson, CD Batson, CD Batson, D Fetherstonhaugh, D Kahneman, D Kahneman, D Watson, D Watson, D. Kahneman, DA Long, DA Small, Dorina Hysenbelli, E Peters, E Peters, E Rubaltelli, Enrico Rubaltelli, F Ali, F. Andrei, G Matthews, HH Freudenthaler, J Andreoni, J Sheng, J. Cohen, JK Gardner, KE Stanovich, KV Petrides, KV Petrides, KV Petrides, KV Petrides, KV Petrides, KV Petrides, KV Petrides, LJ Axelrod, M Mikolajczak, M Mikolajczak, M Singh, MA Brackett, Marina A. Pavlova, ML Hoffman, MT DePalma, N Extremera, N Sevdalis, NT Telle, P Slovic, P Slovic, PA Vernon, RB Cialdini, S Dickert, S Dickert, S Epstein, S Laborde, Sergio Agnoli, T Chamorro-Premuzic, T Kogut, T Kogut, T. Kogut   +57 more
core   +6 more sources

Are left-handers really more anxious? [PDF]

, 2012
Research examining anxiety and handedness is inconclusive. Davidson and Schaffer (1983) found left-handers had higher trait anxiety, while Beaton and Moseley (1991) found no state or trait differences. Such studies potentially have methodological issues,
Hardie, Scott M., Wright, Lynn
core   +2 more sources

Applying trait-based models to achieve functional targets for theory-driven ecological restoration [PDF]

, 2014
Manipulating community assemblages to achieve functional targets is a key component of restoring degraded ecosystems. The response-and-effect trait framework provides a conceptual foundation for translating restoration goals into functional trait targets,
Laughlin, Daniel C.
core   +2 more sources