Results 41 to 50 of about 97,833 (315)

Multi-stage global trajectory optimization for the overlapping shift of a seamless two-speed transmission using Legendre pseudo-spectral method

Advances in Mechanical Engineering, 2017
For a seamless two-speed transmission specially equipped in electric vehicles, the global trajectory optimization problem of the overlapping shift process with multiple stages and complex path/point constraints is investigated in this article.
Jie Ye, Kegang Zhao, Yanwei Liu, Xiangdong Huang, Huibin Lin   +4 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Environmental Impact Assessment, on the Operation of Conventional and More Electric Large Commercial Aircraft [PDF]

, 2013
Global aviation is growing exponentially and there is a great emphasis on trajectory optimization to reduce the overall environmental impact caused by aircraft. Many optimization techniques exist and are being studied for this purpose.
Lawson, Craig P., Seresinhe, R., Sabatini, Roberto   +2 more
core   +1 more source

Unscented Trajectory Optimization

Journal of Guidance, Control, and Dynamics
In a nutshell, unscented trajectory optimization is the generation of optimal trajectories through the use of an unscented transform. Although unscented trajectory optimization was introduced by the authors about a decade ago, it is reintroduced in this paper as a special instantiation of tychastic optimal control theory.
I. Michael Ross, Ronald J. Proulx, Mark Karpenko   +2 more
openaire   +2 more sources

Dynamic analysis with optimum trajectory planning of multiple degree-of-freedom surgical micro-robot

Alexandria Engineering Journal, 2018
The present work aims to analyze kinematics and dynamics accompanied with an optimum trajectory planning, of a multiple degree-of-freedom positioning surgical micro-robot.
Khaled Mohamed, Hassan Elgamal, Amr Elsharkawy   +2 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Research on Wellbore Trajectory Optimization and Drilling Control Based on the TD3 Algorithm

Applied Sciences
In modern oil and gas exploration and development, wellbore trajectory optimization and control is the key technology to improve drilling efficiency, reduce costs, and ensure safety.
Haipeng Gu, Yang Wu, Xiaowei Li, Zhaokai Hou   +3 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Strong Optimality for a Bang-Bang Trajectory [PDF]

SIAM Journal on Control and Optimization, 2002
Summary: We give sufficient conditions for a bang-bang regular extremal to be a strong local optimum for a control problem in the Mayer form; strong means that we consider the \(C^{0}\) topology in the state space. The controls appear linearly and take values in a polyhedron, and the state space and the end point constraints are finite-dimensional ...
A. AGRACHEV, STEFANI, GIANNA, ZEZZA, PIERLUIGI   +2 more
openaire   +3 more sources

Research on Intelligent Optimization of Wellbore Trajectory in Complex Formation

Applied Sciences
Borehole trajectory optimization is a key issue in oil and gas drilling engineering. The traditional wellbore trajectory design method faces great challenges in optimizing the trajectory length and complexity, and it is difficult to meet the actual ...
Haipeng Gu, Tie Yan, Yang Wu
doaj   +1 more source