Results 51 to 60 of about 2,335,287 (233)

On the geometry of Zermelo's optimal control trajectories

open access: yesAUT Journal of Mathematics and Computing, 2022
In the present work, we study the optimal control paths in the Zermelo navigation problem from the geometric and differential equations point of view rather than the optimal control point of view, where the latter has been carried out in our recent work.
Fathi, Zohreh, Bidabad, Behroz
openaire   +3 more sources

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Automatic Vertical Parking Reference Trajectory Based on Improved Immune Shark Smell Optimization

open access: yesAlgorithms
Parking path optimization is the principal problem of automatic vertical parking (AVP); however, it is difficult to determine a collision avoiding, smooth, and accurate optimized parking path using traditional parking reference trajectory optimization ...
Yan Chen   +3 more
doaj   +1 more source

Fast Trajectory Generation Method for Midcourse Guidance Based on Convex Optimization

open access: yesInternational Journal of Aerospace Engineering, 2022
To generate the midcourse guidance trajectory for intercepting the high-speed and high maneuvering target, which is a strongly nonlinear and strongly constrained problem, a two-stage convex optimization method is proposed to solve the optimal trajectory ...
Jinlin Zhang   +4 more
doaj   +1 more source

Regularity of the Hamiltonian Along Optimal Trajectories [PDF]

open access: yesSIAM Journal on Control and Optimization, 2015
This paper concerns state constrained optimal control problems, in which the dynamic constraint takes the form of a differential inclusion. If the differential inclusion does not depend on time, then the Hamiltonian, evaluated along the optimal state trajectory and the co-state trajectory, is independent of time.
Palladino M, Vinter R B
openaire   +6 more sources

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Trajectory planning of unmanned aerial vehicle based on the improved biogeography-based optimization algorithm

open access: yesAdvances in Mechanical Engineering, 2021
This paper is concerned with trajectory planning for unmanned aerial vehicle in a three-dimensional complex workspace. Biogeography-based optimization algorithm is widely used in solving practical problems because of its fewer parameters, fast ...
Zhishuang Xue, Xiaofang Liu
doaj   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

open access: yesAging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

A time-independent trajectory optimization approach for connected and autonomous vehicles under reservation-based intersection control

open access: yesTransportation Research Interdisciplinary Perspectives, 2021
Rule-based and optimization-based autonomous intersection management (AIM) policies have been evaluated against traditional signal controls in terms of intersection safety, efficiency and emission.
Muting Ma, Zhixia Li
doaj   +1 more source

Comparing the Effect of Semi‐Immersive Virtual Reality, Computerized Cognitive Training, and Traditional Rehabilitation on Cognitive Function in Multiple Sclerosis: A Randomized Clinical Trial

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Cognitive impairment is a common non‐motor symptom in Multiple Sclerosis (MS), negatively affecting autonomy and Quality of Life (QoL). Innovative rehabilitation strategies, such as semi‐immersive virtual reality (VR) and computerized cognitive training (CCT), may offer advantages over traditional cognitive rehabilitation (TCR ...
Maria Grazia Maggio   +8 more
wiley   +1 more source

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