Results 111 to 120 of about 94,263 (328)

Inibição da corrente de cálcio tipo L por tramadol e enantiômeros em miócitos cardíacos de ratos Inhibition of L-type calcium current by tramadol and enantiomers in cardiac myocytes from rats

Arquivos Brasileiros de Cardiologia, 2011
FUNDAMENTO: O tramadol é um analgésico de ação central cujo mecanismo de ação envolve a ativação de um receptor opioide. Anteriormente, mostramos que o tramadol e seus enantiômeros apresentavam um efeito inotrópico negativo sobre o músculo papilar no ...
Emiliano Medei, Juliana M. Raimundo, José Hamilton M. Nascimento, Margarete M. Trachez, Roberto T. Sudo, Gisele Zapata-Sudo   +5 more
doaj  

The 2017 Vermont Opioid Prescribing Rules: Prescriber Attitudes [PDF]

, 2018
Introduction. In July of 2017, Vermont enacted new rules on acute opioid pre- scribing to reduce misuse, addiction, and overdose associated with prescription opioids.
Bowden, Zana, Carney, Jan, Cote, Elizabeth, Gandhi, Jinal, Jost, Sarah Natasha, Maclean, Charles, Mathers, Hanna, Serels, Chad, Wigmore, Daniel, Wong, Timothy   +9 more
core   +1 more source

Post-mortem toxicology: A pilot study to evaluate the use of a Bayesian network to assess the likelihood of fatality [PDF]

, 2015
The challenge of interpreting post-mortem drug concentrations is well documented and relies on appropriate sample collection, knowledge of case circumstances as well as reference to published tables of data, whilst taking into account the known issues of
Bolton, Jennifer, Carlin, Michelle, Langford, Alan, Palmer, Ray   +3 more
core   +1 more source

Medication prescription patterns in cancer rehabilitation physiatry outpatients: A multicenter retrospective study

PM&R, EarlyView.
Abstract Background and Objective Previous work from this dataset found 45% prescribing frequency of any medications (35.1%, 33.5%, and 56.8% at institutions 1, 2, and 3 respectively), without significant difference between in‐person and telemedicine.
Matthew Chen, Nafis Eghrari, David Leong, Philip Chang, Jasmine Zheng, Amy Ng, Richard Wilson, Mary Vargo   +7 more
wiley   +1 more source

The Comparison of Preemptive Oral Tramadol, Gabapentin Tramadol and Parasetamol Tramadol Combination on the Efficacy of Postoperative Pain Control in Breast Reduction Surgery

Çukurova Üniversitesi Tıp Fakültesi Dergisi, 2013
Purpose: Application of tramadol by intravenous patient controlled analgesia (PCA) is a routine method for controlling postoperative pain in the breast reduction operations.
Muge Can, Zehra Hatipoglu, Cengiz Eser, Yasemin Gunes   +3 more
doaj  

Randomized Double Blind Comparison of Prophylactic Tramadol and Tramadol Plus Ketamine for Prevention of Shivering after Spinal Anesthesia in Lower Segment Caesarian Section

Journal of the Dow University of Health Sciences
Objective: To assess the effectiveness of prophylactic intravenous tramadol alone versus a combination of tramadol and ketamine in preventing shivering during spinal anesthesia for lower segment caesarean section.
Muhammad Arif, Zeeshan Mirza, Haider Abbas Mandviwala, Sajid Saif, Rabeea Khan, Muhammad Hassam   +5 more
doaj   +1 more source

Hydrogel Microneedle Array‐Based Transdermal Dressing System for Multiplexed Assessment and Intelligent Therapy of Chronic Wounds

Small, EarlyView.
This work develops a theranostic wound microneedle dressing integrates a therapeutic MXene‐infused hydrogel with a high‐conductive sensor array enabled by a novel laser‐scribing technique. The platform actively promotes wound healing and provides antibacterial action while continuously monitoring seven key biomarkers.
Md Sharifuzzaman, Gauri Hasabnis, Sheikh Ahmed Abu Saleh, Leonard Siebert, Jan‐Bernd Hövener, Gregor Maschkowitz, Zeynep Altintas   +6 more
wiley   +1 more source

Neuronal entropy depends on the level of alertness in the parkinsonian globus pallidus in vivo [PDF]

, 2014
A new working hypothesis of Parkinson's disease (PD) proposes to focus on the central role of entropy increase in the basal ganglia (BG) in movement disorders. The conditions necessary for entropy increase in vivo are, however, still not fully described.
Andres, Daniela Sabrina, Cerquetti, Daniel, Merello, Marcelo Jorge, Stoop, Ruedi   +3 more
core   +3 more sources

Post‐Discharge Opioid Prescribing After Elective Colorectal Resection: An International Survey

World Journal of Surgery, EarlyView.
Excessive opioid prescribing after colorectal surgery can lead to adverse events and contribute to the opioid crisis. Understanding international prescribing patterns is essential for guiding practice and future research. The Analgesia After Colorectal Surgery (ACORE) survey aimed to characterize international opioid prescribing practices after ...
Ghadeer Olleik, Hiba Elhaj, Samin Shirzadi, Francesca Fermi, Maxime Lapointe‐Gagner, Sender Liberman, Mohsen Alhashemi, Tahereh Najafi Ghezeljeh, Fatemeh Rajabiyazdi, Nawar Touma, Pepa Kaneva, Agnihotram V. Ramanakumar, Badma Bashankaev, Alexandra Sidorova, Stephen J. Chapman, Chuan‐Gang Fu, Lucia Oliveira, Sofia Valanci, Audrius Dulskas, Steven Wexner, Lawrence Lee, Liane S. Feldman, Marylise Boutros, Julio F. Fiore Jr.   +23 more
wiley   +1 more source

The Tramadol Metabolite O-Desmethyl Tramadol Inhibits Substance P–Receptor Functions Expressed in Xenopus Oocytes

Journal of Pharmacological Sciences, 2011
Tramadol has been widely used as analgesic. O-Desmethyl tramadol (ODT) is one of the main metabolites of tramadol, having much greater analgesic potency than tramadol itself. Substance P receptors (SPR) are well known to modulate nociceptive transmission
Kouichiro Minami, Toru Yokoyama, Junichi Ogata, Yasuhito Uezono   +3 more
doaj   +1 more source