Results 131 to 140 of about 13,664 (199)

Inibição da corrente de cálcio tipo L por tramadol e enantiômeros em miócitos cardíacos de ratos

Arquivos Brasileiros de Cardiologia, 2011
FUNDAMENTO: O tramadol é um analgésico de ação central cujo mecanismo de ação envolve a ativação de um receptor opioide. Anteriormente, mostramos que o tramadol e seus enantiômeros apresentavam um efeito inotrópico negativo sobre o músculo papilar no ...
Emiliano Medei, Juliana M. Raimundo, José Hamilton M. Nascimento, Margarete M. Trachez, Roberto T. Sudo, Gisele Zapata-Sudo   +5 more
doaj  

Tramadol revisited

British Journal of Anaesthesia, 1999
K, Budd, R, Langford
openaire   +2 more sources

Tramadol: a valuable treatment for pain in Southeast Asian countries

, 2018
Ramani Vijayan,1 Gauhar Afshan,2 Khalid Bashir,3 Mary Cardosa,4 Madhur Chadha,5 Pongparadee Chaudakshetrin,6 Khin Myo Hla,7 Muralidhar Joshi,8 Francis O Javier,9 Asif Gul Kayani,10 Andi Takdir Musba,11 Sasikaan Nimmaanrat,12 Dwi Pantjawibowo,13 Jocelyn C
Chadha M, Joshi M, Afshan G, Pantjawibowo D, Vijayan R, Nimmaanrat S, Musba AT, Cardosa M, Que JC, Vijayanand P, Kayani AG, Bashir K, Javier FO, Hla KM, Chaudakshetrin P   +14 more
core  

Premature Ejaculation in the United Kingdom: Variation and Gaps in Contemporary Urological Practice

Trends in Urology &Men's Health, Volume 17, Issue 6, December 2026.
ABSTRACT To present the first nationally disseminated assessment of UK urologists’ perceptions and management of Premature Ejaculation (PE), focusing on alignment with consensus recommendations. A cross‐sectional study was conducted, using anonymised electronic questionnaires distributed to UK urology clinicians following the British Association of ...
Imaad Amanulla, Mohamed Mubarak, Vaibhav Modgil, Theodora Stasinou, Ian Pearce   +4 more
wiley   +1 more source

Local analgesic effect of tramadol is mediated by opioid receptors in late postoperative pain after plantar incision in rats

, 2016
José Oswaldo de Oliveira Junior,1 Milena Fernandes de Freitas,2 Carolina Bullara de Andrade,3 Marucia Chacur,2 Hazem Adel Ashmawi1 1Laboratório de Anestesiologia Experimental, Faculdade de Medicina da Universidade de Sã
Bullara de Andrade C, Ashmawi HA, Chacur M, Oliveira Junior JO, de Freitas MF   +4 more
core  

Opioid Use and Family Members' Experiences of Opioids in Paediatric Cancer Pain Management: An Integrative Review

Scandinavian Journal of Caring Sciences, Volume 40, Issue 4, December 2026.
ABSTRACT Aim To analyse the use of opioids in children with cancer and the experiences of their family members regarding opioids used in pain management to improve family nursing. Design An integrative review. Methods A systematic literature search was carried out in four databases (CINAHL, MEDLINE, PsycInfo and Scopus) in August 2023, and was ...
Noora Puusa, Eeva Harju, Maija‐Liisa Kalliomäki, Elina Haavisto   +3 more
wiley   +1 more source

PARENT-METABOLITE PHARMACOKINETIC MODELS FOR TRAMADOL – TESTS OF ASSUMPTIONS ANDPREDICTIONS [PDF]

, 2014
Allometric principles were used to discern cross-species differences in tramadol disposition and formation of its primary analgesic metabolite, (+)-O-desmethyl-tramadol (M1).
Pypendop B., Holford, Sam, Steinman A., Mehvar, Reza, Pypendop, Bruno, Allegaert K., Kukanich, Butch, Steinmann, Amir, Sousa A. B., Anderson, Brian, Holford, Nick, Holford N., Sousa, Altamir B., Allegaert, Karel, Anderson B. J., Kukanich B., Holford S., GIORGI, MARIO, Mehvar R.   +18 more
core  

Impact of parameter settings on the estimation of drug exposure with the individualized dispensing patterns method

British Journal of Clinical Pharmacology, Volume 92, Issue 11, Page 3982-3991, November 2026.
Aim To assess the impact of parameter settings when using the individualized dispensing patterns (IDP) method to estimate exposure duration from dispensing data. Methods We conducted a cohort study using a 2% representative sample of the French healthcare insurance database from 2013 to 2022.
Laëtitia Gosselin, Clara Lévy, Noémie Sève, Thierry Blanchon, Marianne Sarazin, Louise Rossignol, Maryse Lapeyre‐Mestre, Nathanaël Lapidus, Olivier Steichen   +8 more
wiley   +1 more source

Tramadol and seizures: An overview

, 2011
This review aims to expose the myths and misinterpretations of data concerning the risks of Tramadol Hydrochloride (Tramadol) and seizures within the neurosurgical environment.
Linda Nichols (14745460)
core  

Chiral switches of tramadol hydrochloride, a potential psychedelic drug. Past and future

The chiral opioid analgesic tramadol was patented (1962) as a cis- and trans-racemates mixture. A first chiral switch led to the (+/-)-cis-(1RS,2RS) racemate, patented and approved as Tramal (1980), preferred over the (+)-cis-(1R,2R)-enantiomer ...
D'Acquarica, Ilaria, Agranat, Israel
core   +1 more source