Results 151 to 160 of about 37,856 (275)

Pharmacologie du tramadol

open access: yes, 1997
(+/-)-Tramadol is a synthetic 4-phenyl-piperidine analogue of codeine. It is a central analgesic with a low affinity for opioid receptors. Its selectivity for mu receptors has recently been demonstrated, and the M1 metabolite of tramadol, produced by ...
Collart Leemann, Laurence   +2 more
core  

Characterizing treatment initiation with central nervous system–active polypharmacy among adults with dementia

open access: yesAlzheimer's &Dementia, Volume 22, Issue 6, June 2026.
Abstract INTRODUCTION Central nervous system (CNS) –active polypharmacy, defined as concurrent use of antidepressants, antipsychotics, anti‐seizure medications, benzodiazepines, nonbenzodiazepine benzodiazepine receptor agonists, opioids, or skeletal muscle relaxants for ≥ 31 consecutive days, poses significant risks patients with dementia.
Donovan T. Maust   +9 more
wiley   +1 more source

Low‐dose cannabidiol increases plasma concentrations of amitriptyline: A clinical drug–drug interaction study

open access: yesBritish Journal of Clinical Pharmacology, Volume 92, Issue 6, Page 1595-1606, June 2026.
Abstract Aims Cannabidiol (CBD), the main non‐intoxicating compound from the cannabis plant, is regularly used by patients with chronic pain who also take analgesics. CBD has previously been shown to inhibit CYP‐mediated drug metabolism. This study aimed to characterize the potential pharmacokinetic interaction of CBD with amitriptyline and tramadol ...
Andriy A. Gorbenko   +9 more
wiley   +1 more source

New Technique for Tramadol Dose Accuracy: Are Dosing Pumps the Solution? [PDF]

open access: yesPharmaceuticals (Basel)
Alas-Pineda C   +5 more
europepmc   +1 more source

ACMD consideration of tramadol.

open access: yes, 2013
Briefing from the Chair of the ACMD to the UK Home Secretary and Secretary of State for Health on Tramadol. Tramadol is a synthetic analogue of the phenanthrene alkaloid codeine and is an analgesic of significant medical use for treating moderate to ...

core  

Clinical pharmacology and prescribing education: An updated medical school curriculum from the British Pharmacological Society

open access: yesBritish Journal of Clinical Pharmacology, Volume 92, Issue 6, Page 1787-1808, June 2026.
Aims Prescribing is a complex, essential skill that doctors must acquire to practice medicine safely and effectively. The British Pharmacological Society has historically provided a core curriculum to guide clinical pharmacology and prescribing education in UK medical schools.
Dagan O. Lonsdale   +5 more
wiley   +1 more source

Tramadol and seizures: An overview

open access: yes, 2011
This review aims to expose the myths and misinterpretations of data concerning the risks of Tramadol Hydrochloride (Tramadol) and seizures within the neurosurgical environment.
Linda Nichols (14745460)
core  

Consistency and clarity of pharmacogenomic guidance in UK medicine patient information leaflets: A cross‐sectional analysis

open access: yesBritish Journal of Clinical Pharmacology, Volume 92, Issue 6, Page 1934-1939, June 2026.
Pharmacogenomic (PGx) information has the potential to support the safe and effective use of medicines, yet there is uncertainty about how this information can be best communicated to patients. Summaries of product characteristics (SmPCs) and patient information leaflets (PILs) for all UK‐approved medicines with strong evidence supporting a PGx ...
Parth Narlawar   +5 more
wiley   +1 more source

Dried blood spot analysis in antidoping: Technical challenges, analytical advances, and future perspectives

open access: yesBulletin of the Korean Chemical Society, Volume 47, Issue 6, Page 674-688, June 2026.
Dried blood spot (DBS) analysis enables minimally invasive blood collection with strong analyte stability and simplified logistics, supporting anti‐doping applications beyond traditional matrices. Recent advances address hematocrit, volume variability, and matrix effects while expanding coverage to steroid esters, World Anti‐Doping Agency‐listed ...
Jihyun Yoon   +4 more
wiley   +1 more source

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