Results 111 to 120 of about 13,664 (199)

Opioid use, disability, and patient‐reported cognitive impairment in migraine: Multi‐country results from the Chronic Migraine Epidemiology and Outcomes—International Study

Headache: The Journal of Head and Face Pain, EarlyView.
Plain Language Summary Opioids are widely used to treat migraine despite being contrary to clinical guidelines. In the Chronic Migraine Epidemiology and Outcomes–International (CaMEO‐I) Study, a large, international survey of people with migraine, opioid users were more likely than nonusers to experience moderate or severe migraine‐related disability ...
Elizabeth Leroux, Dawn C. Buse, Michel Lanteri‐Minet, Fumihiko Sakai, Manjit Matharu, Zaza Katsarava, Kristina M. Fanning, Karen Carr, Nicole Naccara, Janette Contreras‐De Lama, Richard B. Lipton   +10 more
wiley   +1 more source

Trends in Dispensing of Opioids and Benzodiazepines Among Older Adults Admitted for an Acute Hip Fracture Between 2008 and 2024 in Ontario, Canada

Journal of the American Geriatrics Society, EarlyView.
ABSTRACT Introduction Opioids and benzodiazepines (BZDs) are commonly prescribed for managing pain, anxiety, and sleep‐related problems following a hip fracture. Both opioids and BZDs carry risks of persistent dependence, falls, and mortality with long‐term use. Despite these risks, Canada lacks standardized prescribing guidelines for older adults with
Anum Ali, Mina Tadrous, Chizaram Eje, Laleh Rashidian, Arrani Senthinathan, Cherry Chu, Kerry Kuluski, Sara J. T. Guilcher   +7 more
wiley   +1 more source

Patient-controlled intravenous tramadol versus patient-controlled intravenous hydromorphone for analgesia after secondary cesarean delivery: a randomized controlled trial to compare analgesic, anti-anxiety and anti-depression effects

, 2018
Guangyou Duan,1,* Xiaohang Bao,1,* Guiying Yang,1 Jing Peng,1 Zhuoxi Wu,1 Peng Zhao,1 Zhiyi Zuo,2 Hong Li1 1Department of Anesthesiology, Xinqiao Hospital, Third Military Medical University, Chongqing 400037, China; 2Department of Anesthesiology ...
Yang G, Wu Z, Li H, Zuo Z, Bao X, Zhao P, Duan G, Peng J   +7 more
core  

Clinical practices in the management of cervical Hansen type I intervertebral disc herniation among veterinary neurologists in North America and Europe

Journal of Small Animal Practice, EarlyView.
Objectives To describe current clinical practices in the management of cervical Hansen type I intervertebral disc herniation among American College of Veterinary Internal Medicine/European College of Veterinary Neurology neurologists. Materials and Methods An anonymous web‐based survey was distributed via professional listservs between October and ...
A. Mondino, M. Riobó, N. J. Olby, S. Moore, P. J. Early   +4 more
wiley   +1 more source

Tramadol and o-desmethyl tramadol clearance maturation and disposition in humans: a pooled pharmacokinetic study.

, 2015
BACKGROUND AND OBJECTIVES We aimed to study the impact of size, maturation and cytochrome P450 2D6 (CYP2D6) genotype activity score as predictors of intravenous tramadol disposition. METHODS Tramadol and O-desmethyl tramadol (M1) observations in
Beier, Horst, Holford, Sam, de Hoon, Jan N, Troconiz, Inaki, Holford, Nick, Anderson, Brian J, Anderson, Brian, de Hoon, Jan, Stamer, Ulrike, Pedersen, Rasmus S, Rochette, Alain, Allegaert, Karel, Trocóniz, Iñaki F, Stuber, Frank, Pedersen, Rasmus S., Stuber, F, Rochette, A, Allegaert, K, Holford, S, Holford, N, Trocóniz, IF, Anderson, BJ, Pedersen, RS, de Hoon, JN, Beier, H, Stamer, U   +25 more
core   +1 more source

Parasomnias and sleep‐related movement disorders induced by drugs in the adult population: a review about iatrogenic medication effects

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary Parasomnias and sleep‐related movement disorders (SRMD) are major causes of sleep disorders and may be drug induced. The objective of this study was to conduct a systematic review of the literature to examine the association between drug use and the occurrence of parasomnias and SRMD.
Sylvain Dumont, Vanessa Bloch, Agnès Lillo‐Lelouet, Christine Le Beller, Pierre A. Geoffroy, Marc Veyrier   +5 more
wiley   +1 more source

Tramadol and delirium [PDF]

Anaesthesia, 2015
N, Rughooputh, R, Griffiths
openaire   +2 more sources

Veterinary Pharmaceutical Safety Competencies for New Graduates: Description of an Interprofessional Simulated Learning Activity

Journal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT The misuse and abuse of veterinary anesthetic and analgesic agents pose significant public health risks, particularly with the growing presence of ultrapotent opioids and other anesthetics in the illicit drug trade. In response, there is increasing emphasis on incorporating medication safety training into veterinary curricula.
Margene Anderson, Carrie Schroeder, Kristopher M. Schroeder   +2 more
wiley   +1 more source

Miotic action of tramadol is determined by CYP2D6 genotype

, 2006
Polymorphic CYP2D6 is the enzyme that activates the opioid analgesic tramadol by O-demethylation to M1. Our objective was to determine the opioid effects measured by pupillary response to tramadol of CYP2D6 genotyped volunteers in relation to the ...
Kvetina, J, Mikoviny, R, Zima, T, Idle, J R, Nobilis, M, Perlík, F, Slanar, O   +6 more
core  

Pharmacogenomics in Dentistry: From CYP‐Mediated Drug Response to Precision Prescribing in Oral Healthcare

Oral Diseases, EarlyView.
ABSTRACT Objective This narrative review critically assesses the clinical relevance of pharmacogenomics within dental genomics, distinguishing clinically actionable applications from emerging or investigational findings. Materials and Methods A targeted literature review was conducted in PubMed/MEDLINE, Scopus and Embase for publications from January ...
Giorgia Pieretto, Jessica Cusato, Martina Sansavini, Christian Bacci   +3 more
wiley   +1 more source