Results 121 to 130 of about 67,803 (253)
Stereochemical Studies on a New Ciramadol Analogue by NMR-Spectroscopy [PDF]
, 1994 The absol. configuration of a Ciramadol analogue obtained from (-)-menthone is established by 'H-NMR-. simulated NMR-, COSY-90-, and NOEmeasurements. The final compound 2-(a-1 -pyrrolidino)benzy 1-4-isopropyl- 1 -methyl-cyclohexan-3-one (4b), e.g..
Akgün, H. +4 more
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Equine Veterinary Education, EarlyView.Summary Alpha‐2‐adrenoreceptor agonists provide analgesia when used as sole agents but can also be used in combination with other drugs for their additive and potentially synergistic effects. Further, because of their effects on blood flow, alpha‐2‐adrenoreceptor agonists act to extend and perhaps intensify the effects of drugs, such as local ...
J. Brandly +4 more
wiley +1 more source
Headache: The Journal of Head and Face Pain, EarlyView.Abstract Objective The primary objective of this study was to evaluate opioid and barbiturate utilization before and after the first prescription of the calcitonin gene–related peptide receptor antagonist rimegepant in individuals with migraine. Background Although not recommended in migraine treatment guidelines, opioids and barbiturates are often ...
Noah Rosen +6 more
wiley +1 more source
Microneedles for the treatment of migraine and orofacial pain: A narrative review
Headache: The Journal of Head and Face Pain, EarlyView.Abstract Background Migraine is a common neurological disorder and a primary headache condition. Despite its central origin, migraine pain may be referred to the orofacial region via trigeminal pathways, resulting in phenotypic overlap with other orofacial pain (OFP) conditions.
Baicheng Cao +6 more
wiley +1 more source
A look inside the association codeine-paracetamol: clinical pharmacology supports analgesic efficacy [PDF]
, 2015 Acute and chronic pain often requires a multimodal approach. Combination therapy reduces the number of individual daily administrations and improves patient's compliance with the prescribed analgesic treatment. Despite the association codeine/paracetamol
COLUZZI, FLAMINIA, MATTIA, Consalvo
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The raphe nuclear organization and serotonergic system in the bat (Artibeus planirostris)
Journal of Anatomy, EarlyView.Schematic representation of the methodological workflow used to characterize the serotonergic (5‐HT) system in the bat Artibeus planirostris. Serotonin (5‐HT) immunohistochemistry was performed on brainstem sections to identify and map the distribution of serotonergic neurons within the raphe nuclei.
Mariana D. Leite +9 more
wiley +1 more source
Inibição da corrente de cálcio tipo L por tramadol e enantiômeros em miócitos cardíacos de ratos
Arquivos Brasileiros de Cardiologia, 2011 FUNDAMENTO: O tramadol é um analgésico de ação central cujo mecanismo de ação envolve a ativação de um receptor opioide. Anteriormente, mostramos que o tramadol e seus enantiômeros apresentavam um efeito inotrópico negativo sobre o músculo papilar no ...
Emiliano Medei +5 more
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