Results 131 to 140 of about 94,263 (328)

Association of Tramadol-Induced Ovarian Damage and Reproductive Dysfunction with Adenosine Triphosphate and the Protective Role of Exogenous ATP Treatment

Pharmaceuticals
Background: Tramadol, a weak opioid analgesic agent, is known to induce ovarian damage. Previous studies have held oxidative stress responsible for the adverse effects of tramadol on female reproduction.
Neset Gumusburun, Ilhan Bahri Delibasi, Seval Bulut, Halis Suleyman, Betul Kalkan Yilmaz, Taha Abdulkadir Coban, Ali Sefa Mendil, Zeynep Suleyman   +7 more
doaj   +1 more source

Opioids in breast cancer: Between analgesia and modulation of tumour progression

British Journal of Pharmacology, EarlyView.
Preclinical investigations consistently demonstrate that activation of μ‐opioid receptors and δ‐opioid receptors promote proliferation, migration, angiogenesis, epithelial‐mesenchymal transition, acquisition of cancer stem cell phenotypes, and chemoresistance.
Marianna Ciwun, Anna Tankiewicz‐Kwedlo, Dariusz Pawlak   +2 more
wiley   +1 more source

Facilitators to the continuous abuse of tramadol among the youth: A qualitative study in Northern Ghana

Nursing Open, 2019
Considering the alarming rate at which young people abuse tramadol, as evidenced by the numerous media reports on the subject, this qualitative study was conducted to explore the facilitators to the abuse of tramadol by young people.
Abdul-Ganiyu Fuseini, Alhassan Afizu, Yakubu H. Yakubu, Gilbert Nachinab   +3 more
semanticscholar   +1 more source

Reduction of opioid and barbiturate use following initiation of rimegepant for migraine in the United States

Headache: The Journal of Head and Face Pain, EarlyView.
Abstract Objective The primary objective of this study was to evaluate opioid and barbiturate utilization before and after the first prescription of the calcitonin gene–related peptide receptor antagonist rimegepant in individuals with migraine. Background Although not recommended in migraine treatment guidelines, opioids and barbiturates are often ...
Noah Rosen, Aaron Jenkins, Karin Hygge Blakeman, Feng Dai, Lucy Abraham, Chelsea Leroue, Josh Brown   +6 more
wiley   +1 more source

Litigation-Ending Sanctions: Alaska Courts’ Use of Rule 37 [PDF]

, 1985
Pain is a common symptom of a number of conditions including cancer and one of the most frequent reasons for seeking healthcare. Acute and chronic pain result in considerable discomfort with a detrimental impact on the quality of life.
Carroll, Robert
core   +1 more source

The raphe nuclear organization and serotonergic system in the bat (Artibeus planirostris)

Journal of Anatomy, EarlyView.
Schematic representation of the methodological workflow used to characterize the serotonergic (5‐HT) system in the bat Artibeus planirostris. Serotonin (5‐HT) immunohistochemistry was performed on brainstem sections to identify and map the distribution of serotonergic neurons within the raphe nuclei.
Mariana D. Leite, Andréa S. M. Bandeira, Wigínio G. L. Bandeira, Milena S. Lustosa, Ana C. F. Gama, Marília A. S. Barros, Paulo L. A. G. Morais, Jeferson S. Cavalcante, Melquisedec A. D. Santana, Expedito S. Nascimento Jr   +9 more
wiley   +1 more source

Optimization of Carboxymethyl-Xyloglucan-Based Tramadol Matrix Tablets Using Simplex Centroid Mixture Design [PDF]

, 2012
Ashwini Madgulkar, Mangesh R. Bhalekar, Rahul Padalkar, Mohseen Y. Shaikh   +3 more
openalex   +1 more source

Dutch Pharmacogenetics Working Group (DPWG) guideline for the gene–drug interaction between CYP2D6 and opioids (codeine, tramadol and oxycodone)

European Journal of Human Genetics, 2021
Maja Matic, M. Nijenhuis, Bianca Soree, Nienke J. de Boer-Veger, Anne M Buunk, E. Houwink, H. Mulder, G. Rongen, J. Weide, B. Wilffert, J. Swen, H. Guchelaar, V. Deneer, R. V. van Schaik   +13 more
semanticscholar   +1 more source

Analgesic practices for acute pain management in cats and dogs in Africa

Journal of Small Animal Practice, EarlyView.
Objectives To understand perceptions and analgesic practices for acute pain management in cats and dogs by veterinarians in Africa. Materials and Methods Data from small animal veterinarians were collected using an online questionnaire (English/French) and convenience sampling.
S. S. U. H. Bukhari, J. C. Murrell, N. Lutevele, A. R. Ajadi, P. V. Steagall, B. P. Monteiro   +5 more
wiley   +1 more source

A randomized, double-blind, placebo-controlled, crossover trial of "on-demand" tramadol for treatment of premature ejaculation

Urology Annals, 2015
Objectives: The objective of this study is to assess the dose-related effects of tramadol on a group of patients with premature ejaculation (PE).
Adel Kurkar, Ahmad A Elderwy, Sherief Abulsorour, Sara M Awad, Ahmed S Safwat, Ahmed Altaher   +5 more
doaj   +1 more source