Results 81 to 90 of about 13,664 (199)

DrugWatch information sheet: Tramadol.

, 2018
Tramadol is a centrally acting analgesic structurally related to codeine. It has multiple actions: after entering the body it breaks down (metabolises) mainly into O-desmethyltramadol which acts on opioid receptors and also affects levels of serotonin ...
Adley, Mark
core  

Challenges of Pain in Parkinson's Disease: Results from the OCEAN Study

Movement Disorders, EarlyView.
Abstract Background Pain is a common non‐motor symptom in Parkinson’s disease (PD) and is often associated to fluctuations. Objective The OpiCapone Effect on motor fluctuations and pAiN (OCEAN) study evaluated the effect of opicapone on fluctuation‐related pain when added to levodopa therapy in PD patients.
Kallol Ray Chaudhuri, Joaquim J. Ferreira, Angelo Antonini, Olivier Rascol, Monica M. Kurtis, Alexander Storch, José‐Francisco Rocha, Raquel Costa, Diogo Magalhães, Guillermo Castilla‐Fernández, Helena C. Brigas, Joerg Holenz, Per Odin, on behalf of the OCEAN study group   +13 more
wiley   +1 more source

PENGARUH PEMBERIAN ANALGESIK KOMBINASI PARASETAMOL DAN TRAMADOL TERHADAP KADAR SERUM GLUTAMAT PIRUVAT TRANSAMINASE

Jurnal Kedokteran Diponegoro, 2017
Latar Belakang : Kombinasi parasetamol dan tramadol merupakan analgesik kombinasi yang ideal dan efektif dalam menangani nyeri derajat sedang sampai berat. Keduanya bekerja pada mekanisme berbeda dalam penangan nyeri.
Peggy Rahmat Syahputra, Taufik Eko Nugroho   +1 more
doaj   +1 more source

Towards Responsible Mining in Africa: Problematising the Environmental and Public Health Concerns of Artisanal and Small‐Scale Gold Mining in Ghana

Sustainable Development, EarlyView.
ABSTRACT There have been emerging media reports on the impact of cyanide and mercury use in artisanal and small‐scale gold mining (ASGM) operations on community health, especially among pregnant and non‐pregnant women, ASGM miners, and children in rural Africa.
Francis Arthur‐Holmes, Emmanuel Selasi Tomude, Steve Ahenkora Amoako   +2 more
wiley   +1 more source

Laponite Network Controls FGF‐2 Release and Drives Functional Nerve Regeneration via 3D‐Printed Nerve Wrap Interfaces

Small Methods, EarlyView.
We developed a 3D‐printed nerve interface integrating a biomimetic nanocomposite hydrogel with sustained delivery of thermostable FGF‐2. The bioactive interface supports Schwann cell activity and myelination while providing a regenerative microenvironment.
Diego N. Rodriguez‐Sanchez, Akshat Joshi, Saeed Safari, Leticia A. M. de Carvalho, Kevin S. Muller, Uijin Kim, Luciana P. Cartarozzi, Meenakshi Kamaraj, Menekse Ermis, Natan R. de Barros, Alexandre L. R. de Oliveira   +10 more
wiley   +1 more source

Pharmacologie du tramadol

, 1997
(+/-)-Tramadol is a synthetic 4-phenyl-piperidine analogue of codeine. It is a central analgesic with a low affinity for opioid receptors. Its selectivity for mu receptors has recently been demonstrated, and the M1 metabolite of tramadol, produced by ...
Collart Leemann, Laurence, Desmeules, Jules Alexandre, Dayer, Pierre, Collart L, Desmeules J, Dayer P   +5 more
core   +1 more source

Protodesnitazene: The identification and tissue distribution of a new nitazene

Journal of Forensic Sciences, EarlyView.
Abstract Multiple new analogues from the 2‐benzyl benzimidazole or “nitazene” class of drugs have emerged on the drug market in recent years. Nitazenes are highly potent μ‐opioid receptor agonists that present a substantial public health concern due to their elevated risk of severe toxicity in overdose and their significant potential for misuse.
Andrew Griffiths, Nathan Milne, Michelle Johnston, Karen Blakey, Rogan Scott   +4 more
wiley   +1 more source

The comparison of the efficacy of preemptive oral gabapentin - tramadol combination and parasetamol - tramadol combination on the postoperatif tramadol consumption.

, 2011
TEZ9232Tez (Uzmanlık) -- Çukurova Üniversitesi, Adana, 2011.Kaynakça (s. 49-53) var.viii, 54 s. : tablo ; 29 cm.Amaç: Postoperatif ağrı kontrolünde rutin uygulanan yöntemlerden birisi intravenöz yoldan hasta kontrollü analjezi (HKA) ile tramadol ...
Can, Müge
core   +1 more source

Inibição da corrente de cálcio tipo L por tramadol e enantiômeros em miócitos cardíacos de ratos Inhibition of L-type calcium current by tramadol and enantiomers in cardiac myocytes from rats

Arquivos Brasileiros de Cardiologia, 2011
FUNDAMENTO: O tramadol é um analgésico de ação central cujo mecanismo de ação envolve a ativação de um receptor opioide. Anteriormente, mostramos que o tramadol e seus enantiômeros apresentavam um efeito inotrópico negativo sobre o músculo papilar no ...
Emiliano Medei, Juliana M. Raimundo, José Hamilton M. Nascimento, Margarete M. Trachez, Roberto T. Sudo, Gisele Zapata-Sudo   +5 more
doaj  

Population pharmacokinetic analysis of tramadol and O-desmethyltramadol with genetic polymorphism of CYP2D6

, 2019
Joomi Lee,1,* Hee-Doo Yoo,2,* Jung-Woo Bae,3 Sooyeun Lee,3 Kwang-Hee Shin11College of Pharmacy, Research Institute of Pharmaceutical Sciences, Kyungpook National University, Daegu, Republic of Korea; 2Department of Biostatistics and Bioinformatics ...
Lee S, Bae JW, Lee J, Shin K, Yoo H
core