Results 141 to 150 of about 21,301 (157)

MYC-Mediated Resistance to Trametinib and HCQ in PDAC Is Overcome by CDK4/6 and Lysosomal Inhibition

Journal of Experimental Medicine, 2023
Jeffrey Yap, Dilru Silva, Conan G Kinsey
exaly  

Trametinib Potentiates TRAIL-Induced Apoptosis via FBW7-Dependent Mcl-1 Degradation in Colorectal Cancer Cells

Journal of Cellular and Molecular Medicine, 2020
Shijun Li
exaly  

A Randomized Phase II Study of the MEK1/MEK2 Inhibitor Trametinib (GSK1120212) Compared With Docetaxel in KRAS-Mutant Advanced Non-Small-Cell Lung Cancer (NSCLC)

Annals of Oncology, 2015
Jun Hwee Kim, Julien Mazieres, T de Pas
exaly  

Dabrafenib Plus Trametinib Versus Dabrafenib Monotherapy in Patients With Metastatic BRAF V600E/K-Mutant Melanoma: Long-Term Survival and Safety Analysis of a Phase 3 Study

Annals of Oncology, 2017
Jochen Utikal, John B A G Haanen, Claus Garbe   +2 more
exaly  

Dabrafenib and Trametinib Versus Dabrafenib and Placebo for Val600 BRAF-Mutant Melanoma: A Multicentre, Double-Blind, Phase 3 Randomised Controlled Trial

Lancet, The, 2015
Jochen Utikal, James Larkin, John B A G Haanen   +2 more
exaly  

A Phase IB Trial of the Oral MEK Inhibitor Trametinib (GSK1120212) in Combination With Everolimus in Patients With Advanced Solid Tumors

Annals of Oncology, 2015
J R Infante, K P Papadopoulos, J C Bendell   +2 more
exaly  

Functional and Symptom Impact of Trametinib Versus Chemotherapy in BRAF V600E Advanced or Metastatic Melanoma: Quality-of-Life Analyses of the METRIC Study

Annals of Oncology, 2014
Claus Garbe, Reinhard Dummer, Caroline Robert   +2 more
exaly  

Characteristics of Pyrexia in BRAFV600E/K Metastatic Melanoma Patients Treated With Combined Dabrafenib and Trametinib in a Phase I/II Clinical Trial

Annals of Oncology, 2015
Alexander M Menzies, Georgina V. Long, Adil Daud   +2 more
exaly  

Open-Label, Phase IIa Study of Dabrafenib Plus Trametinib in East Asian Patients With Advanced BRAF V600-Mutant Cutaneous Melanoma

European Journal of Cancer, 2020
Sang Joon Shin, Tae Min Kim, Yun Fan
exaly  

Study of Molecular Mechanism of the Interaction Between MEK1/2 and Trametinib With Docking and Molecular Dynamic Simulation

Interdisciplinary Sciences, Computational Life Sciences, 2019
Fatemeh Ramezani, Hashem Rafii-Tabar
exaly