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Prehospital tranexamic acid for trauma victims
Journal of Intensive Care, 2023 The public enquiry into the mass casualty incident at the Manchester Arena in the UK in which 23 people died and over 1000 were injured, identified the need for timely intramuscular administration of tranexamic acid to trauma patients.Kazuhiko Omori, Ian Robertsdoaj +2 more sourcesTranexamic acid at cesarean delivery: Drug‐error deaths
BJOG: an International Journal of Obstetrics and Gynaecology, 2022 The use of tranexamic acid for postpartum hemorrhage has entered obstetrical practice globally with the evidence‐based expectation of saving lives. This improvement in the care of women with postpartum hemorrhage has come at a price. For the anesthetist, Neil Moran, David G. Bishop, Susan Fawcus, Edward Morris, Haleema Shakur‐Still, Adam Devall, Ioannis Gallos, Mariana Widmer, Olufemi T. Oladapo, Arri Coomarasamy, G Justus Hofmeyr +10 moreopenalex +2 more sourcesEffect of early tranexamic acid administration on mortality, hysterectomy, and other morbidities in women with post-partum haemorrhage (WOMAN): an international, randomised, double-blind, placebo-controlled trial [PDF]
The Lancet, 2017 Background
Post-partum haemorrhage is the leading cause of maternal death worldwide. Early administration of tranexamic acid reduces deaths due to bleeding in trauma patients.Aasia Kayani, Abalaka Aye, Abdalla Mohammed, Abdulfetah Abdulkadir, Abdulfetah Abdulkadir, Abdulfetah Abdulkadir, Abdulrasaq Sambo, Abida Sajid, Abiodun Aboyeji, Abiodun Adeniran, Abraham Onwe, Abu Kholdun, Adebayo Adewale, Adebola Owodunni, Adeniyi Fasanu, Adesina Akintan, Adesina Akintan, Adetunji Adeniji, Adeyemi Okunowo, Ado Geidam, Adolphe Somé, Adrian Grant, Aferdita Kruja, Affiss Adelodun, Afshan Batool, Ahmad Kazumari, Aisha Iftikhar, Ajay Agrawal, Akhtar Sherin, Akintunde Ayinde, Akpojaro Ikpen, Alex Nyakundi Bosire, Alexander Kawimbe, Alfred Osoti, Alia Bano, Alice Ashu, Alice Ntem, Alison Bates, Alysha Allibone, Amadou Ly, Amadou Ndouoya, Amaitari Bariweni, Ambreen Ikram, Amos Otara, Amtullah Zarreen, Andrea Jogo, Andrew Sharpe, André Simo, Angeline Njoache, Aniefiok Umoiyoho, Anita Ali, Anna Danford, Anthony Kwame Dah, Anthony Massinde, Antony Wanjala, Arafat Ifemeje, Armida Tola, Asia Nazir, Asma Baloch, Audu Idrisa, Augustine Adeniyi, Austin Ojo, Awadia Ali, Ayesha Mobeen, Ayiko Jackson, Babalola Adeyemi, Babalola Adeyemi, Babasola Okusanya, Babatunde Adebudo, Babatunde Awolaja, Badibanga Musau, Bamidele Adeleye, Bartthy Okorochukwu, Basharat Ahmad, Bellington Vwalika, Bellington Vwalika, Bellington Vwalika, Bernadette Nakawooya Lwasa, Berno Mwambe, Besnik Brahimaj, Beverley Hunt, Bhola Ram Shrestha, Blessed Adeyemi, Bonface Musila, Brian Liyayi, Brigadier Naila, Bukola Fawole, Bukola Fawole, Bukola Fawole, Carine Ronsmans, Carine Ronsmans, Carroli, Carys Smith, Catherine Gilliam, Cesar Sanchez, Chapman, Charles Kacha, Chris Aimakhu, Christine Biryabarema, Christine Namulwasira, Christine Nanyongo, Chrstine Biryabarema, Clare Tower, Collette Barrow, Dachollom Audu, Daniel Gilbert, Daniel Onwusulu, Danielle Beaumont, Danielle Beaumont, Danielle Prowse, David Isah, Dawn Edmundson, Desire Tshombe, Dewan, Diana Elbourne, Dominic Drametu, Dorothy Keka, Ducloy-Bouthors, Duria Rayis, Egbaname Aigere, Elhassan Safa, Elizabeth Buligho, Elizabeth Ndagire, Elizabeth Nionzima, Emily Nzeribe, Emmanuel Byaruhanga, Emmanuel Gbejegbe, Emmanuel Inyang-Etoh, Emmanuel Okpako, Eni Balogun, Enyinnaya Chikwendu Nduka, Eta Ngole Mbong, Etienne Asonganyi, Etienne Asonganyi, Eugene Oteng-Ntim, Evelyn Muthoka, Ezekiel Ladan, Eziamaka Pauline Ezenkwele, Ezukwa Omoronyia, Faiza Aleem, Faiza Nassir, Fareesa Waqar, Farjana Basher, Faryal Sardar, Farzana Burki, Fatimah Habeebu-Adeyemi, Fehmida Shaheen, Felix Okogbo, Ferdousi Chowdhury, Ferdousi Islam, Fikre Geremew, Folasade Oyelade, Fouzia Gul, Francis Alu, Francis Banya, Gabriel Essetchi Faye, George Bugg, George Mtove, Georges Nko'ayissi, Getachew Ayana, Ghazala Taj, Gilda Piaggio, Gillian Houghton, Gladys Dibia, Glen Mola, Grace Adekola-Oni, Grace Akinbinu, Grace Meregurwa, Gulfareen Arain, Gyanendra Karki, Habiba Sharaf Ali, Hadia Mustafa, Hadiza Galadanci, Hadiza Idris, Hailemariam Segni, Hajaratu Sulayman, Hajira Masood, Hakim Miah, Hala Abdullahi, Haleema Hashmi, Haleema Shakur, Haleema Shakur, Haleema Shakur, Hassen Hussien, Henry Mwangi, Henry Opare-Addo, Herman Kalyana, Hillary Mabeya, Hina Rajani, Horace Fletcher, Huida Almardi, Huida Eltaib, Huma Quddusi, Hussein Iman, Hussein Khamis, Hussein Kidanto, Hussein Kidanto, Hussein Kidanto, Iain Chalmers, Ian Roberts, Ian Roberts, Ian Roberts, Ian Roberts, Ibrahim Habib, Ifeoma Offiah, Ikemefuna Nwosu, Ilir Tasha, Isabirye Rebecca, Isaiah Hansingo, Jacob Awoleke, Jane Mumba, Jean Robert Lubamba, Jeanne Fouedjio, Jeharat Gul, Jim Thornton, Joanne Wilkins, John Ogudu, Joselyn Ayikoru, Joseph Agulebe, Joseph Ikechebelu, Joseph Ngonzi, Josiah Mutihir, Kamil Shoretire, Kaosar Afsana, Kastriot Dallaku, Kastriot Dallaku, Kato Faida, Kayode Olayinka, Kayode Oluwatosin, Kehinde Ologunde, Kenfack Bruno, Ker, Ker, Khadija Mayumba, Khalid Elfadl, Khidir Awadalla, Kim Hinshaw, Kiran Jabeen, Kiran Javaid, Kruithof, Kubasu Wekesa, Kusasira Anitah, Kwadwo Nyarko-Jectey, Lamaran Dattijo, Lauren Frimley, Lawrence Omo-Aghoja, Lema Felix, Leon Kaza, Leonard Madame, Leslie Samuels, Liliana Vallecilla, Lin Barneston, Lisa Cook, Lubna Bashir, Lubna Dar, Lubna Kahloon, Lucky Oyeye, Magdy El Rahman, Magreth Zacharia, Mahdi Bushra, Mahwish Jamil, Maimoona Hafeez, Maimoona Munawar, Maliha Zafar, Malts Wai, Manahil Jaffer, Margret Nankya, Maria Fernanda Escobar, Maria Ramos, Mariam Tariq, Mark Ogbiti, Martin Saadio, Mateus Sahani, Mateus Sahani, Mathew Ng'ambi, Matilda Ngarina, Mesack Tchana, Metin Gülmezoglu, Metin Gülmezoglu, Misbah Harim, Mohamed Ahmed, Mohamed El-Sheikh, Mohamed El-Sheikh, Mohammed Gana, Mohammed Musa, Mohan Regmi, Mohan Regmi, Mohd Chohan, Moses Alao, Moussa Bambara, Murwan Ibrahim, Musarrat Jabeen, Musimbi Soita, Muzdalifat Abeid, Mwansa Ketty Lubeya, Mwansa Lubeya, Myles, Nabia Tariq, Nabila Salman, Nadia Sadiq, Naila Israr, Naila Israr, Nakirigya Nuulu, Nankat Joseph, Naseem Saba, Naseema Usman, Nasira Tasnim, Nayiga Annet, Nazlima Nargis, Nazneen Begum, Neelam Surhio, Nick Grace, Nicolas Meda, Nigel Quashi, Nighat Shaheen, Nike Bello, Nikita Dhakal, Nilofar Mustafa, Nishat Akram, Nji Eric, Nkeiruka Ameh, Nkonwa Innocent, Nneka Madueke, Noah Olaomo, Noojiri Bopili, Noonari Mukhtiar, Nurudeen Onaolapo, Nzanzu Kikuhe Jason, Odel Gwan, Odidika Umeora, Okpe James, Ola Nene Okike, Ola Okike, Olabisi Loto, Oladapo, Oladapo Olayemi, Oladapo Olayemi, Olaide Salau, Olalekan Awonuga, Olatunde Onafowokan, Olubunmi Ladipo, Olufemi Abidoye, Olufemi Akinsanya, Olufemi Odekunle, Olugbenga Akintunde, Olujide Okunade, Olusade Adetayo, Olusegun Ajenifuja, Oluseyi Adelekan, Oluwabusola Monehin, Oluwarotimi Akinola, Oluwaseun Adeyemi, Omer Babiker, Omololu Adegbola, Onyebuchi Udegbunam, Osagie Osayande, Owigho Opreh, Palmer Henry, Pascal Foumane, Patrick Komagum, Paul Ayuk, Paul Kua, Pauline Assomo, Peninah Waigi, Peter Achara, Phanny Simisi, Phil Edwards, Philemon Nsem, Pierre Marie Tebeu, Pisake Lumbiganon, Pramila Pradhan, Prieto-Merino, Punita Yadav, Pushpa Sachdev, Qurratul Ain, Rabia Batool, Rabindra Bhatt, Raheela Asmat, Rashida Sultana, Razia Khero, Regina Akello, Riffat Shaheen, Riham Desougi, Rita Atim, Rizwana Chaudhri, Rizwana Chaudhri, Rizwana Chaudhri, Rizwana Chaudhri, Roamba Pabakba, Rob Jackson, Robert Tchounzou, Robert Tchounzou, Roberts, Roderick Larsen-Reindorf, Roger Paluku-Hamuli, Rokeya Begum, Ronsmans, Rophina Msengeti, Rose Bwotya, Rose Wangui, Roseline Iheagwam, Roshan Qazi, Rubina Hussain, Rubina Sohail, Rukhsana Karim, Ruth Bulime, Rwakyendela Onesmo, Saba Javed, Sabaratnam Arulkumaran, Sadaf Mufti, Sadaqat Jabeen, Sadia Khan, Saeed Abdelrahman Abdelgabar, Saeeda Majeed, Safia Khalil, Saima Iqbal, Saimir Cenameri, Saira Dars, Sajila Karim, Salma Khudaidad, Samana Aleem, Samar Amin, Samina Dojki, Samina Iqbal, Samina Kausar, Samina Manzoor, Samirra Ahmed, Sanobar Ashfaq, Sara Saeed, Sarah Babirye, Saturday Etuk, Saturday Etuk, Sawamura, Say, Sayeba Akhter, Sayeba Akhter, Sebastian Kitengile Ganyaka, Serge Mulyumba, Sergey Kostrov, Shabana Rizvi, Shabween Masood, Shah, Shahela Jesmin, Shahenzad Sohail, Shahid Rao, Shakur, Shakur, Shama Chaudhry, Shamayela Hanif, Shamsa Humayun, Shamsunnisa Sadia, Sharmeen Arshad, Shazia Batool, Shazia Rasul, Shazia Sultana, Shehla Manzoor, Shehla Noor, Shehla Noor, Shrodha Paul, Shyam Gupta, Simeon Bazuaye, Sofia Manzoor, Sola Abubakar, Somia Abdelrahiem, Sophia Udonwa, Sumaya Huque, Summera Aslam, Sununu Yusuf, Swati Singh, Syeda Mazhar, Syeda Rabia Bukhari, Taemi Kawahara, Taha Umbeli, Tahir Kyani, Tahira Batool, Tasneem Ashraf, Tayyiba Wasim, Temitope Onile, Theresa Azonima Irinyenikan, Tom Godec, Tony Brady, Tort, Tracey Pepple, Ubong Akpan, Uduak Udofia, Umar Ibrahim, Umbreen Akram, Useneno Okon, Uzma Shaheen, Venantius Mutsu, Veronicah Ongwae, Victor Wanjohi, Vincent Oyiengo, Wafaa Basta, Willard Mtambo, William Golit, William Haleke, Willies Silwimba, Willis Missumba, Wisal Nabag, Wu, Yinka Amode, Ymele Fouelifack, Yusuf Baffah Adamu, Zahida Qureshi, Zahida Qureshi, Zahida Qureshi, Zarko Alfirevic, Zarko Alfirevic, Zarko Alfirevic, Zeinab Zubier, Ziche Makukula +511 morecore +4 more sourcesPrevention of haematoma progression by tranexamic acid in intracerebral haemorrhage patients with and without spot sign on admission scan: a statistical analysis plan of a pre-specified sub-study of the TICH-2 trial [PDF]
BMC Research Notes, 2018 Objective We present the statistical analysis plan of a prespecified Tranexamic Acid for Hyperacute Primary Intracerebral Haemorrhage (TICH)-2 sub-study aiming to investigate, if tranexamic acid has a different effect in intracerebral haemorrhage ...Christian Ovesen, Janus Christian Jakobsen, Christian Gluud, Thorsten Steiner, Zhe Law, Katie Flaherty, Rob A. Dineen, Philip M. Bath, Nikola Sprigg, Hanne Christensen +9 moredoaj +7 more sourcesTranexamic acid for acute intracerebral haemorrhage growth based on imaging assessment (TRAIGE): a multicentre, randomised, placebo-controlled trial
Stroke and Vascular Neurology, 2021 Background Studies show tranexamic acid can reduce the risk of death and early neurological deterioration after intracranial haemorrhage. We aimed to assess whether tranexamic acid reduces haematoma expansion and improves outcome in intracerebral ...Liping Liu, Yuehua Pu, Yongjun Wang, Yan Wang, Xingquan Zhao, Hongqiu Gu, Qi Zhou, Yibin Cao, Wenzhi Wang, Dacheng Liu, Jingyi Liu, Haixin Sun, Zhonghua Yang, Ximing Nie, Miao Wen, Shengjun Sun, Ying Tan, Lina Zheng, Jiahui Zhao, Haomeng Zhu, Yunpeng Zhang, Lijin Yi +21 moredoaj +2 more sourcesTranexamic acid reduces intraoperative occult blood loss and tourniquet time in obese knee osteoarthritis patients undergoing total knee arthroplasty: a prospective cohort study
Therapeutics and Clinical Risk Management, 2018 Yutong Meng,1,* Zhirui Li,1,2,* Ke Gong,1 Xiao An,2 Jiyuan Dong,1 Peifu Tang1 1Department of Orthopedics, Chinese PLA General Hospital, Beijing, China; 2Department of Orthopedics, Chinese PLA General Hospital Hainan Branch, Sanya, China *These authors ...Meng Y, Li Z, Gong K, An X, Dong J, Tang P +5 moredoaj +3 more sources
