Results 1 to 10 of about 5,067,781 (348)

THE EFFECT OF TRANEXAMIC ACID INJECTION ON HEMOGLOBIN LEVEL, ALBUMIN LEVEL, AND PAIN ON PATIENT RECEIVING TOTAL KNEE REPLACEMENT [PDF]

Journal Orthopaedi and Traumatology Surabaya, 2019
Background: The high number of knee osteoarthritis cases could lead arthroplasty more frequent. Total Knee Replacement (TKR) surgery procedure is at risk of massive bleeding.
Dwikora Novembri Utomo, Teddy Heri Wardhana, Ahmad Hannan Amrullah, Hamzah Hamzah   +3 more
doaj   +2 more sources

Tranexamic acid for surgical bleeding. [PDF]

BMJ, 2014
Uncertainty over vascular occlusive events warrants an adequately powered RCT Joint replacement accounts for a large share of the 230 million major operations carried out each year worldwide. Each year in England and Wales alone there are about 180 000 hip and knee replacements.1 Bleeding is an important complication, and many patients require a blood
Ker, Katharine, Roberts, Ian
core   +5 more sources

Prevention of haematoma progression by tranexamic acid in intracerebral haemorrhage patients with and without spot sign on admission scan: a statistical analysis plan of a pre-specified sub-study of the TICH-2 trial [PDF]

BMC Research Notes, 2018
Objective We present the statistical analysis plan of a prespecified Tranexamic Acid for Hyperacute Primary Intracerebral Haemorrhage (TICH)-2 sub-study aiming to investigate, if tranexamic acid has a different effect in intracerebral haemorrhage ...
Christian Ovesen, Janus Christian Jakobsen, Christian Gluud, Thorsten Steiner, Zhe Law, Katie Flaherty, Rob A. Dineen, Philip M. Bath, Nikola Sprigg, Hanne Christensen   +9 more
doaj   +7 more sources

Topical tranexamic acid prevents scar tissue formation following craniectomy in a rat model [PDF]

European Journal of Medical Research
Background We carried out a study to assess the efficacy of tranexamic acid in preventing scar tissue in the craniectomy area in rats. Method Our study consisted of control and tranexamic acid groups with 10 subjects each.
Ömer Şahin, Tuncer Taşcıoğlu, Ayşegül Fırat, Hüseyin Selçuk Sürücü, Muzaffer Çaydere   +4 more
doaj   +2 more sources

Aprotinin may increase mortality in low and intermediate risk but not in high risk cardiac surgical patients compared to tranexamic acid and ε-aminocaproic acid - a meta-analysis of randomised and observational trials of over 30.000 patients [PDF]

, 2013
Background: To compare the effect of aprotinin with the effect of lysine analogues (tranexamic acid and ε-aminocaproic acid) on early mortality in three subgroups of patients: low, intermediate and high risk of cardiac surgery.
Herrmann, Eva, Meybohm, Patrick, Nierhoff, Julia, Zacharowski, Kai   +3 more
core   +11 more sources

Efficacy of oral Tranexamic Acid in reducing blood loss during primary total hip arthroplasty: A comparative study

Ibom Medical Journal, 2023
Background: Perioperative blood loss is a major concern for patients undergoing total hip arthroplasty. Intravenous Tranexamic acid is commonly used to reduce blood loss and need for blood transfusion following total hip replacement. Recent studies have
Essien UE, Inyang UC, Itakpe SE, Lawal WO, Dim EM, Usendiah IB   +5 more
doaj   +1 more source

Tranexamic acid-induced focal convulsions after spinal surgery: a rare case report and literature review on side effects of accidental spinal administration of tranexamic acid

EFORT Open Reviews, 2023
Convulsions are a neurological illness that has complexity. In clinical treatment, drug-induced convulsions appear from time to time. Drug-induced convulsions often begin as isolated acute seizures but may progress to persistent seizures. In orthopedics,
Hua Luo, Chaojun Shen, Tongyou Qu, Lin Chen, Yue Sun, Yu Ren   +5 more
doaj   +1 more source

Effect of tranexamic acid administration on intraoperative blood loss during peritonectomy: a single-center retrospective observational study

JA Clinical Reports, 2023
Background The efficacy of tranexamic acid in elective major invasive abdominal surgeries has not yet been established. We investigated the effect of tranexamic acid administration on intraoperative blood loss during peritoneal resection of ...
Daiki Shirasu, Masahiko Tsuchiya, Noriaki Oomae, Wataru Shirasaka, Tatsuhiko Iino, Daisuke Hirano, Makoto Satani   +6 more
doaj   +1 more source

Trauma and tranexamic acid [PDF]

Medical Journal of Australia, 2013
Research is needed to determine how patient selection and intercurrent treatment affect safety and efficacyClinicians involved in the resuscitation of severely injured patients face a dilemma. On one hand, since publication of the landmark CRASH-2 (Clinical Randomisation of an Antifibrinolytic in Significant Haemorrhage 2) study in 2010, there has been
Gruen, Russell L., Jacobs, Ian G., Reade, Michael C.   +2 more
openaire   +4 more sources

Plasma Concentrations of Tranexamic Acid in Postpartum Women After Oral Administration. [PDF]

, 2020
OBJECTIVE: To evaluate the pharmacokinetics of tranexamic acid after oral administration to postpartum women. METHODS: We conducted a single-center pharmacokinetic study at Teaching Hospital-Jaffna, Sri Lanka, on 12 healthy postpartum women who delivered
Arulkumaran, S, Balakumar, S, Muhunthan, K, Navaratnaraja, TS, Premakrishna, S   +4 more
core   +1 more source