Results 91 to 100 of about 5,067,781 (348)

The Effectiveness of Intravenous Tranexamic Acid on Blood Loss and Surgical Time During Endoscopic Sinus Surgery: A Systematic Review

open access: yesPhilippine Journal of Otolaryngology Head and Neck Surgery, 2018
Objective: To review the effectiveness of intravenous tranexamic acid in reduction of blood loss, surgical time and field visualization among patients who underwent endoscopic sinus surgery (ESS) for chronic rhinosinusitis (CRS).
Jona Minette E. Ligon   +1 more
doaj   +1 more source

Evaluating Tranexamic Acid Dosing Strategies for Postpartum Hemorrhage: A Population Pharmacokinetic Approach in Pregnant Individuals

open access: yesThe Journal of Clinical Pharmacology, EarlyView.
Abstract Tranexamic acid (TXA) is used for the treatment and occasionally prevention of postpartum hemorrhage (PPH); however, questions still remain regarding dosing regimen optimization. This study evaluated TXA pharmacokinetic (PK) data from four clinical trials (NCT: 04274335, 03287336, 00872469, and 02797119) conducted in pregnant participants ...
Allison Dunn   +12 more
wiley   +1 more source

Effect of tranexamic acid on coagulation and fibrinolysis in women with postpartum haemorrhage (WOMAN-ETAC): a single-centre, randomised, double-blind, placebo-controlled trial [PDF]

open access: yes, 2018
Background: Postpartum haemorrhage (PPH) is a leading cause of maternal death. The WOMAN trial showed that tranexamic acid (TXA) reduces death due to bleeding in women with PPH.
Adetayo, Cecilia   +17 more
core   +3 more sources

East Midlands Research into Ageing Network (EMRAN) Discussion Paper Series [PDF]

open access: yes, 2019
Academic geriatric medicine in Leicester . There has never been a better time to consider joining us. We have recently appointed a Professor in Geriatric Medicine, alongside Tom Robinson in stroke and Victoria Haunton, who has just joined as a ...
Agarwal, S.   +29 more
core  

Applying results from clinical trials: tranexamic acid in trauma patients. [PDF]

open access: yes, 2014
This paper considers how results from clinical trials should be applied in the care of patients, using the results of the Clinical Randomisation of an Antifibrinolytic in Significant Haemorrhage (CRASH-2) trial of tranexamic acid in bleeding trauma ...
Prieto-Merino, David, Roberts, Ian
core   +1 more source

Bowel habits in preterm infants: Observations from the first 2 weeks of life

open access: yesJournal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Uniform descriptions of normal preterm infant bowel habits are lacking, causing ambiguity in identifying abnormal bowel habits in this population. This study examines preterm infants' bowel habits and their association with maternal and infant factors in the first 2 weeks of life. Methods An observational study included infants with
Ulrikke Lyng Beauchamp   +4 more
wiley   +1 more source

Hereditary hypofibrinogenemia: A rare cause of chronic liver disease

open access: yesJPGN Reports, EarlyView.
Abstract Hypofibrinogenemia is characterized by low levels of fibrinogen with patients commonly presenting asymptomatically. This report discusses a case of hereditary hypofibrinogenemia manifesting as chronic liver disease in a 2‐year‐old male who was evaluated for elevated liver enzymes and skin/soft tissue bleeding.
Hannah Caringal   +4 more
wiley   +1 more source

Effect of tranexamic acid on mortality in patients with haemoptysis: a nationwide study

open access: yesCritical Care, 2019
Background Although tranexamic acid is widely used in patients with haemoptysis, whether it improves mortality has not been well investigated. The aim of this study was to evaluate the effect of tranexamic acid on in-hospital mortality among patients ...
Takahiro Kinoshita   +5 more
doaj   +1 more source

A high-dose 24-hour tranexamic acid infusion for the treatment of significant gastrointestinal bleeding: HALT-IT RCT

open access: yesHealth Technology Assessment, 2021
Background: Tranexamic acid reduces blood loss in surgery and the risk of death in trauma patients. Meta-analyses of small trials suggest that tranexamic acid decreases the number of deaths from gastrointestinal bleeding, but these meta-analyses are ...
Ian Roberts   +29 more
doaj   +1 more source

Menstrual suppression to decrease intrauterine device expulsion in adolescents with inherited bleeding disorders

open access: yes
International Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 421-423, April 2025.
Peter H. Cygan   +3 more
wiley   +1 more source

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