Results 71 to 80 of about 33,417 (194)

Does Combined Intravenous and Topical Tranexamic Acid Offer Additional Benefit Compared With Intravenous or Topical Alone in Open Elbow Arthrolysis—A Pilot Randomized Controlled Trial

Orthopaedic Surgery, EarlyView.
Open elbow arthrolysis is a common method for treating post‐traumatic elbow stiffness. Intravenous, topical, or combined tranexamic acid administration showed no significant difference in reducing postoperative blood loss after open elbow arthrolysis. However, both combined and topical tranexamic acid significantly reduced postoperative drainage volume
Chen Chen, Jianyu Zhang, Kehan Hua, Weitong Sun, Dan Xiao, Maoqi Gong, Yejun Zha, Xieyuan Jiang   +7 more
wiley   +1 more source

Tranexamic acid dosing in pediatric trauma: Dose simulation based on population pharmacokinetic modeling in adult trauma patients

Transfusion, EarlyView.
Abstract Background Trauma is the most common cause of death in children >1 year of age, with hemorrhage being the most common preventable cause of death after injury. Antifibrinolytics like tranexamic acid (TXA) are a key aspect of trauma management in children, but optimal dosing remains unknown.
Gideon Stitt, Kevin Downes, Athena Zuppa, Christine Leeper, Kevin Watt, Philip Spinella   +5 more
wiley   +1 more source

Применение транексамовой кислоты при эндопротезировании крупных суставов [PDF]

, 2013
КРОВОПОТЕРЯ ХИРУРГИЧЕСКАЯСУСТАВЫТРАНЕКСАМОВАЯ КИСЛОТА ...
Борисов, Д. Б., Киров, М. Ю.   +1 more
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Endothelial thrombomodulin—Its role in trauma‐induced coagulopathy

Transfusion, EarlyView.
Abstract Background Trauma‐induced coagulopathy (TIC) describes a complex set of coagulation changes affecting severely injured patients. The thrombomodulin‐protein C axis is central to the evolution of TIC. Soluble thrombomodulin (sTM) levels are elevated after injury and predict poor clinical outcomes.
Jeries Abu‐Hanna, Gael B. Morrow, Gang Xu, Lewis Timms, Naveed Akbar, Michael Laffan, Robin P. Choudhury, Nicola Curry   +7 more
wiley   +1 more source

Declaring futility after traumatic injury and the burden of failure on the surgeon

Transfusion, EarlyView.
Abstract In this edition of the THOR supplement in Transfusion, there are two articles that deal with resuscitation futility and transfusion. In one article, Yazer et al. delve into the details of the studies outlined in this editorial and summarize the literature on the topic of transfusion and futility. The second article by Dr.
Jan‐Michael Van Gent, Bryan A. Cotton
wiley   +1 more source

Elevating the standards of hypofibrinogenemia in trauma: Higher thresholds of admission fibrinogen predict mortality and organ dysfunction

Transfusion, EarlyView.
Abstract Background The precise thresholds at which admission fibrinogen predicts mortality and organ dysfunction in trauma patients are unknown. Study Design and Methods Retrospective study at a single trauma center. Inclusion criteria: 18–89 years, traumatic mechanism, transported from scene, and fibrinogen obtained within 30‐min of arrival ...
Justin Richards, Joseph Kufera, Mary Burgoyne, Deborah Stein, Rosemary Kozar   +4 more
wiley   +1 more source

Propofol‐Related Infusion Syndrome in Paediatrics—Cautious Consideration or Considered Caution? Case Report

Journal of Paediatrics and Child Health, EarlyView.
Michael A. Stokes, Mark A. J. Dexter, Stephen Jacobe, Jonathan R. Egan, Cindy G. Berrueta Rodriguez, Ashfaque Quadir   +5 more
wiley   +1 more source

Patient blood management and surgery: Impact of new surgical techniques on transfusion needs

Vox Sanguinis, EarlyView.
Abstract Background and Objectives Patient blood management (PBM) is a multidisciplinary approach aimed at reducing the use of blood products. It considers the patient's own blood as a valuable resource to preserve and seeks to avoid the routine use of transfusions to treat anaemia.
Francois Ansart, France Pirenne
wiley   +1 more source

Parenteral iron—Does it increase infection risk?

Vox Sanguinis, EarlyView.
Abstract Background and Objectives Iron deficiency (ID) and iron deficiency anaemia (IDA) are prevalent conditions impacting various patient populations, both surgical and non‐surgical conditions. The advent of patient blood management (PBM) has promoted intravenous (IV) iron therapy as an alternative to oral iron and blood transfusions.
Joyisa Deb, Aswin K. Mohan, Suhasini Sil, Suvro Sankha Datta, Yoghini Nagandran, Manideepa Maji, Mohammad Kamrul Hassan Majumder, Saikat Mandal   +7 more
wiley   +1 more source

An update on the management of anticoagulated patients programmed for dental extractions and surgery [PDF]

, 2008
Oral anticoagulants (OACs) antagonizing vitamin K - fundamentally sodium warfarin and acenocoumarol - are widely used for preventing arterial thromboembolism in patients with atrial fibrillation and/or heart valve prostheses, and for the treatment and ...
Gavaldá Esteve, Carmen, Jiménez Soriano, Yolanda, Margaix Muñoz, María, Poveda Roda, Rafael, Sarrión Pérez, María Gracia   +4 more
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