Results 61 to 70 of about 33,417 (194)

Exploring redundant research into the effect of tranexamic acid on surgical bleeding: further analysis of a systematic review of randomised controlled trials. [PDF]

, 2015
OBJECTIVES: We examined whether apparent redundancy in a cumulative meta-analysis of trials is justified by concern about bias, random error or generalisability of the results.
Ker, Katharine, Roberts, Ian
core   +1 more source

Inherited Bleeding Disorders in Pregnancy: Obstetric Management and Outcomes From a Tertiary Care Centre

Haemophilia, EarlyView.
ABSTRACT Objective This study aimed to evaluate the obstetric management, complications and clinical characteristics of pregnant women diagnosed with hereditary coagulation factor deficiencies at a tertiary obstetric centre over a 10‐year period. Methods We retrospectively reviewed a total of 19 pregnancies in 17 women with hereditary coagulation ...
Melis Altug Inan, Bilge Kapudere, Hanne Bulat Cim, Abdulkadir Turgut   +3 more
wiley   +1 more source

Delphi Consensus Recommendations for the Definition of a Severe Bleeding Phenotype and Initiation of Prophylaxis in Patients With Non‐Severe Haemophilia

Haemophilia, EarlyView.
ABSTRACT Introduction Current guidelines recommend prophylaxis for patients with non‐severe haemophilia with severe bleeding phenotype (SBPT) but there is no consensus how to define a SBPT and when to recommend prophylaxis in patients with non‐severe haemophilia. Method A Delphi consensus procedure among the members of the Standing Committee Hemophilia
Christian Pfrepper, Cihan Ay, Ralf Knöfler, Christoph Königs, Manuela Krause, Wolfgang Miesbach, Johannes Oldenburg, Michael Sigl‐Kraetzig, Rosa Sonja Alesci, Martin Olivieri, for the Standing Committee Hemophilia of the GTH   +10 more
wiley   +1 more source

Should We Use Preoperative Epoetin-α in the Mildly Anemic Patient Undergoing Simultaneous Total Knee Arthroplasty? [PDF]

, 2013
Simultaneous knee arthroplasty is associated with significant blood loss. To prevent transfusion, three preoperative doses of epoetin-α were offered to mildly anemic simultaneous knee arthroplasty patients.
Blair, Jamie L, Delasotta, Lawrence A, Jafari, S Mehdi, Ong, Alvin, Orozco, Fabio   +4 more
core   +2 more sources

Assessing the Impact of the 2021 VWD Guidelines on the Diagnosis/Management of Low VWF Patients

Haemophilia, EarlyView.
ABSTRACT Introduction The 2021 ASH/ISTH/NHF/WFH VWD diagnosis guidelines recommend Type 1 VWD diagnoses for patients with (a) VWF <0.30 IU/mL or (b) ‘Low VWF’ 0.30–0.50 IU/mL with the presence of abnormal bleeding. This recommendation recategorizes ‘Low VWF’ patients with abnormal bleeding into Type 1 VWD.
Michael Dong, Joanna Larson, Sepideh Saroukhani, Miguel Escobar, Lakshmi Srivaths   +4 more
wiley   +1 more source

Rare Bleeding Disorders and Bleeding Disorder of Unknown Cause: Current Understanding and Recent Developments

Haemophilia, EarlyView.
ABSTRACT Rare bleeding disorders (RBDs) represent a diverse group of inherited conditions involving coagulation factors or platelets. These conditions, such as Glanzmann thrombasthenia (GT) or severe coagulation factor deficiencies, are uncommon. In contrast, bleeding disorder of unknown cause (BDUC) is a diagnosis of exclusion without an identifiable ...
Alessandro Casini, Robert Klamroth, Bauke Haisma, Dino Mehic, Saskia E. M. Schols   +4 more
wiley   +1 more source

بررسی اثرات استفاده از ترانکسامیک اسید وریدی در کاهش میزان خونریزی اعمال جراحی هرنیاسیون دیسک کمری با دو روش بیهوشی استنشاقی و بیهوشی کامل داخل وریدی [PDF]

, 2007
زمینه و هدف: ترانکسامیک اسید یک داروی آنتی‌فیبرینولیتیک است که موجب کاهش خونریزی و نیاز به تزریق خون در اعمال جراحی قلب و آرتروپلاستی مفصل زانو می‌شود.
جلائيان‌تقـدمي, رضا, مشهدي‌نژاد, حسين, پيـوندي, آرش   +2 more
core  

Dental extraction in patients rece iving dual antiplatelet therapy [PDF]

, 2015
Background: Dual antiplatelet therapy consists of administering antiplatelet (antiaggregant) drugs (clopidogrel and aspirin) to prevent thrombotic processes, as a preventative measure in patients with acute coronary disease, or in patients ...
Calvo Guirado, José Luis, González Jaranay, Maximino, Gómez Moreno, Gerardo, Moreu Burgos, Gerardo, Peñarrocha Diago, Miguel, Rodriguez Archilla, Alberto, Sánchez Cobo, Paulino, Sánchez Palomino, Paulino   +7 more
core   +2 more sources

Investigator‐Led Research to Improve the Diagnostic Assessment of Platelet Function Disorders: Reflections on the Challenges and Rewards

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Introduction Investigator‐led research and quality improvement initiatives have led to important improvements in the diagnostic assessment of platelet function disorders (PFD). Methods Personal reflections were used to summarize our contributions to knowledge on PFD diagnostic assessment, pathogenesis, and bleeding risks.
Catherine P. M. Hayward
wiley   +1 more source

Platelet Levels Associated With Bleeding Risk for Dental Interventions: A Systematic Review

Oral Diseases, EarlyView.
ABSTRACT Objectives To evaluate evidence in relation to postoperative bleeding in humans aged ≥ 16 with preoperative platelet counts < 50,000/μL, compared to those above, undergoing dental interventions. Methods Quantitative synthesis without meta‐analysis was conducted through an electronic search conducted on Ovid MEDLINE and Embase from 1946 to ...
Guang Xu David Lim, Fatima Al Sarraf, Hana Cho, Navdeep Kumar   +3 more
wiley   +1 more source