Results 91 to 100 of about 33,417 (194)

Carrier screening in the reproductive setting—Are there medical implications for the heterozygote?—A guide for clinicians

Pregnancy, Volume 2, Issue 3, May 2026.
Abstract Carrier screening for genetic conditions performed preconception or during pregnancy allows identification of fetal risk for inherited autosomal recessive and X‐linked conditions. The goal is to identify at‐risk patients/couples and offer them reproductive options such as preimplantation genetic diagnosis, prenatal testing, or targeted newborn
Emily B. Rosenfeld, Nicole Kasatkin, Bi Liu Yu, Milen Velinov, Justin S. Brandt, Elena Ashkinadze   +5 more
wiley   +1 more source

Global consensus on the management of melanin hyperpigmentation disorders

Journal of the European Academy of Dermatology and Venereology, Volume 40, Issue 5, Page 760-772, May 2026.
A global Delphi consensus of 10 dermatology experts established evidence‐based recommendations for melanin hyperpigmentation disorders, providing unified classification, photoprotection guidance and treatment algorithms. This framework harmonizes terminology and supports individualized management across diverse skin types and health systems.
Thierry Passeron, Seemal R. Desai, Marwa Abdallah, Firas Al‐Niaimi, Ncoza Dlova, Pearl E. Grimes, Jorge Ocampo‐Candiani, Rashmi Sarkar, Leihong Flora Xiang, Helio Amante Miot   +9 more
wiley   +1 more source

Factor XIII Supplementation in Postpartum Hemorrhage: From Biological Rationale to Clinical Implementation

American Journal of Hematology, Volume 101, Issue 4, Page 794-806, April 2026.
ABSTRACT Postpartum hemorrhage (PPH) remains the leading cause of preventable maternal mortality despite standard interventions. Recent fibrinogen trials failed to improve outcomes, prompting interest in coagulation factor XIII (FXIII). FXIII functions as “molecular cement,” cross‐linking fibrin and stabilizing clots.
Jeremy W. Jacobs, Elizabeth A. Abels, Brian D. Adkins, Garrett S. Booth, Victoria Costa, Sheharyar Raza, Michelle Simon, Jennifer S. Woo, Allison P. Wheeler   +8 more
wiley   +1 more source

Biliary Complication Under Nonoperative Management in High‐Grade Liver Injury: A Case Report

Clinical Case Reports, Volume 14, Issue 4, April 2026.
ABSTRACT In children, nonoperative management (NOM) of (isolated) blunt solid organ injury is an established treatment method in hemodynamically stable patients. Although close monitoring and meticulous reevaluation are mandatory, complications may occur and may need diagnostic or therapeutic adjuncts.
Jonathan Lovis, Marco Schmitz, Remus Frei, Thomas Krebs, Frank‐Martin Häcker, Christoph Matissek   +5 more
wiley   +1 more source

Intractable Delayed Bleeding After Endoscopic Submucosal Dissection for Early Gastric Cancer in Patients With Chronic Disseminated Intravascular Coagulation Caused by Aortic Aneurysm

DEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT Chronic disseminated intravascular coagulation (DIC) is a rare complication of an aortic aneurysm (AA), and it may go unnoticed because patients are often asymptomatic. The condition is sometimes first recognized when trauma or an invasive procedure triggers a sudden and severe difficulty in achieving hemostasis.
Hiroyuki Endo, Waku Hatta, Noriyuki Obara, Kasumi Hishinuma, Tomoyuki Koike, Atsushi Masamune   +5 more
wiley   +1 more source

Safety and Efficacy of Tranexamic Acid in Hepatic Surgery: Systematic Review and Meta‐Analysis of Randomized Controlled Trials

Journal of Surgical Oncology, Volume 133, Issue 5, Page 607-615, April 2026.
ABSTRACT Tranexamic acid (TXA) is widely used across surgical specialties to reduce perioperative blood loss, yet its specific role in hepatic resection remains unclear. This meta‐analysis, performed according to PRISMA guidelines, evaluated the efficacy and safety of TXA in liver surgery.
Haris Yaseen, Muhammad Haris Khan, Maurish Fatima, Qasim Mehmood, Luqman Bashir, Kathryn Wittrock, Hassan Aziz   +6 more
wiley   +1 more source

Pediatric Post‐Tonsillectomy Hemorrhage Management: A Cross‐Sectional Otolaryngology and Emergency Medicine Survey

Laryngoscope Investigative Otolaryngology, Volume 11, Issue 2, April 2026.
ABSTRACT Objectives To evaluate current trends and management strategies for post‐tonsillectomy hemorrhage (PTH) among otolaryngology (ENT) and emergency medicine (EM) physicians. Methods A survey was developed by a panel of pediatric ENT, critical care, and EM physicians. Questions assessed therapies and definitions of PTH.
Dylan Z. Erwin, Andrew D. Meyer, Matthew Y. Liu, Alexander M. Nunnery, Whitney W. Schwarz, Marisa A. Earley, Mark R. Zonfrillo   +6 more
wiley   +1 more source

Platelet‐rich fibrin matrix as treatment for complex anal fistulae: A 3‐year experience at a tertiary centre

Colorectal Disease, Volume 28, Issue 4, April 2026.
Abstract Aim Treatment of complex anal fistulae remains a significant challenge for physicians and patients. A sphincter‐preserving technique with bioactive platelet‐rich fibrin matrix is one option. This three‐year study aimed to evaluate the efficacy of bioactive platelet‐rich fibrin matrix in treating complex anal fistulae. Method This retrospective
Alejandro Lusilla Lopez, Ursula Aho Fält, Pamela Buchwald, Louis Banka Johnson, Olof Grip   +4 more
wiley   +1 more source

Multimodal Approach for Recalcitrant Melasma Using Picosecond Laser and Topical JAK Inhibition: A Case Report

Journal of Cosmetic Dermatology, Volume 25, Issue 4, April 2026.
ABSTRACT Background Melasma is a chronic hyperpigmentation disorder with high relapse rates, particularly in Fitzpatrick skin types III–V. Increasing evidence implicates cytokine‐driven inflammation and visible light–induced melanogenesis as key contributors to disease persistence.
Hasan Ashkanani, Maryam AlZaabi, Abdulaziz AlRasheed, Wael AlDaraji   +3 more
wiley   +1 more source

Mortality associated with administration of high-dose tranexamic acid and aprotinin in primary open-heart procedures: a retrospective analysis [PDF]

, 2010
Michael Sander, Claudia D Spies, Viktoria Martiny, Christoph Rosenthal, Klaus-Dieter Wernecke, Christian von Heymann   +5 more
core   +1 more source