Results 31 to 40 of about 5,005,447 (264)

Assessment of the effect of tranexamic acid on perioperative bleeding in pediatric patients undergoing tonsillectomy

Egyptian Journal of Anaesthesia, 2015
Background: Tonsillectomy is one of the most common surgery in pediatric and bleeding is one of the most serious complications related to tonsillectomy. Tranexamic acid is a plasminogen inhibitor which has been successfully used to control bleeding in a ...
Rabie Soliman, Ali Alshehri
doaj   +1 more source

Comparing the Efficacy of Patelet-rich Plasma (PRP) versus Tranexamic Acid (4mg/mL) as Intradermal Treatments of Melasma.

Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2021
OBJECTIVE To compare the efficacy of intradermal platelet-rich-plasma vs. intradermal tranexamic acid in treatment of melasma. STUDY DESIGN Non-randomised controlled trial.
M. Mumtaz, Tahir Hassan Chandio, Mohammad Shahzad, Nazia Hanif, Sarah Anwar, Saira Rafique   +5 more
semanticscholar   +1 more source

Myoclonus, Seizure, and Ventricular Fibrillation after Intrathecal Injection of Tranexamic Acid [PDF]

Journal of Tehran University Heart Center, 2009
Tranexamic acid is generally used in the treatment of disorders that predispose one to bleeding. It is a synthetic lysine analog that has strong antifibrinolytic activity.
Feridoun Sabzi, Hassan Teimouri, Abdolhamid Zokai   +2 more
doaj   +1 more source

Tranexamic Acid During Prehospital Transport in Patients at Risk for Hemorrhage After Injury: A Double-blind, Placebo-Controlled, Randomized Clinical Trial.

JAMA Surgery, 2020
Importance In-hospital administration of tranexamic acid after injury improves outcomes in patients at risk for hemorrhage. Data demonstrating the benefit and safety of the pragmatic use of tranexamic acid in the prehospital phase of care are lacking for
Francis X Guyette, Joshua B. Brown, M. Zenati, Barbara J. Early‐Young, Peter W. Adams, B. Eastridge, R. Nirula, G. Vercruysse, T. O'keeffe, B. Joseph, L. Alarcon, C. Callaway, B. Zuckerbraun, M. Neal, R. Forsythe, M. Rosengart, T. Billiar, D. Yealy, A. Peitzman, J. Sperry   +19 more
semanticscholar   +1 more source

Tranexamic acid to reduce head injury death in people with traumatic brain injury: the CRASH-3 international RCT.

Health Technology Assessment, 2021
BACKGROUND Tranexamic acid safely reduces mortality in traumatic extracranial bleeding. Intracranial bleeding is common after traumatic brain injury and can cause brain herniation and death.
I. Roberts, H. Shakur-Still, A. Aeron-Thomas, D. Beaumont, A. Belli, A. Brenner, Madeleine Cargill, R. Chaudhri, N. Douglas, Lauren Frimley, Catherine Gilliam, A. Geer, Z. Jamal, R. Jooma, Raoul Mansukhani, A. Miners, J. Pott, D. Prowse, T. Shokunbi, Jack Williams   +19 more
semanticscholar   +1 more source

Tranexamic acid-induced fixed drug eruption

Indian Journal of Dermatology, 2015
A 33-year-old male showed multiple pigmented patches on his trunk and extremities after he took tranexamic acid for common cold. He stated that similar eruptions appeared when he was treated with tranexamic acid for influenza 10 months before. Patch test
Natsuko Matsumura, Yuka Hanami, Toshiyuki Yamamoto   +2 more
doaj   +1 more source

Tranexamic acid for intracerebral haemorrhage within 2 hours of onset: protocol of a phase II randomised placebo-controlled double-blind multicentre trial

Stroke and vascular neurology, 2021
Rationale Haematoma growth is common early after intracerebral haemorrhage (ICH), and is a key determinant of outcome. Tranexamic acid, a widely available antifibrinolytic agent with an excellent safety profile, may reduce haematoma growth.
N. Yassi, Henry Zhao, L. Churilov, B. Campbell, Teddy Y. Wu, Henry Ma, A. Cheung, T. Kleinig, H. Brown, P. Choi, J. Jeng, A. Ranta, Hao-kuang Wang, G. Cloud, R. Grimley, D. Shah, N. Spratt, D. Cho, K. Mahawish, L. Sanders, J. Worthington, B. Clissold, A. Meretoja, V. Yogendrakumar, M. D. Ton, Duc Phuc Dang, Nguyen Thai My Phuong, Huy-Thang Nguyen, C. Hsu, G. Sharma, P. Mitchell, B. Yan, M. Parsons, Christopher Levi, G. Donnan, S. Davis   +35 more
semanticscholar   +1 more source

Blood-Preserving Effect of Tranexamic Acid in Knee Joint Replacement

Общая реаниматология, 2008
Objective: to evaluate the efficacy and safety of tranexamic acid in knee joint replacement. Subjects and methods: the prospective open-label study of the efficacy of tranexamic acid as an agent for blood loss reduction in knee joint replacement included
Yu. L. Shevchenko, Yu. M. Stoiko, M. N. Zamyatin, B. A. Teplykh, I. A. Karpov, D. A. Smolkin   +5 more
doaj   +1 more source

Generalizing treatment effects with incomplete covariates: identifying assumptions and multiple imputation algorithms [PDF]

arXiv, 2021
We focus on the problem of generalizing a causal effect estimated on a randomized controlled trial (RCT) to a target population described by a set of covariates from observational data. Available methods such as inverse propensity sampling weighting are not designed to handle missing values, which are however common in both data sources. In addition to
arxiv  

Efficacy and safety of tranexamic acid in the treatment of adult melasma: An updated meta‐analysis of randomized controlled trials

Journal of Clinical Pharmacy and Therapeutics, 2021
Tranexamic acid (TXA) is a novel treatment option for melasma; however, no consensus exists on its use. This study evaluates the efficacy and safety of TXA for melasma.
Xiaowei Feng, H. Su, Jinwei Xie
semanticscholar   +1 more source