Results 31 to 40 of about 5,120,986 (304)

The effect of Tranexamic acid on cardiac surgery bleeding [PDF]

Reviews in Clinical Medicine, 2014
Serious bleeding in cardiac surgery leads to re-exploration, blood transfusion and increases the risks of mortality and morbidity. Using the lysine analogous of antifibrionlytic agents are the preferred strategy to suppress the need for transfusion ...
Mohammad Esmaeelzadeh, Shahram Amini
doaj   +3 more sources

The risk of thromboembolic events with early intravenous 2‐ and 4‐g bolus dosing of tranexamic acid compared to placebo in patients with severe traumatic bleeding: A secondary analysis of a randomized, double‐blind, placebo‐controlled, single‐center trial

Transfusion, 2022
Screening for the risk of thromboembolism (TE) due to tranexamic acid (TXA) in patients with severe traumatic injury has not been performed in randomized clinical trials.
P. Spinella, K. Bochicchio, Kimberly A. Thomas, A. Staudt, Susan M. Shea, A. Pusateri, Douglas J. E. Schuerer, J. Levy, A. Cap, G. Bochicchio   +9 more
semanticscholar   +1 more source

Effect of tranexamic acid in traumatic brain injury: a nested randomised, placebo controlled trial (CRASH-2 Intracranial Bleeding Study). [PDF]

, 2011
OBJECTIVE: To assess the effect of tranexamic acid (which reduces bleeding in surgical patients and reduces mortality due to bleeding in trauma patients) on intracranial haemorrhage in patients with traumatic brain injury.
CRASH-2 Collaborators, Intracranial Bleeding Study
core   +1 more source

Can the prophylactic administration of tranexamic acid reduce the blood loss after robotic-assisted radical prostatectomy? Robotic Assisted Radical Prostatectomy with tranEXamic acid (RARPEX): study protocol for a randomized controlled trial

Trials, 2022
Background The prophylactic administration of tranexamic acid reduces blood loss during procedures at high risk of perioperative bleeding. Several studies in cardiac surgery and orthopedics confirmed this finding.
M. Balik, J. Kosina, P. Husek, J. Pacovsky, M. Brodak, F. Cecka   +5 more
doaj   +1 more source

Use of Tranexamic Acid during Total Endoprosthetic Replacement of the Hip Joint

Общая реаниматология, 2010
Objective: to evaluate the blood-saving activity, efficacy, and safety of tranexamic acid. Subjects and methods. Thirty-seven patients allocated into two groups were enrolled in the study of the efficacy of tranexamic acid as an agent in reducing blood ...
D. D. Selivanov, V. A. Sungurov, V. V. Likhvantsev, D. Ye. Konev, L. A. Moiseikina   +4 more
doaj   +1 more source

Effect of tranexamic acid on thrombotic events and seizures in bleeding patients: a systematic review and meta-analysis

Critical Care, 2021
Background Tranexamic acid (TXA) reduces surgical bleeding and reduces death from bleeding after trauma and childbirth. However, its effects on thrombotic events and seizures are less clear.
Shuhei Murao, Hidekazu Nakata, I. Roberts, K. Yamakawa   +3 more
semanticscholar   +1 more source

Efficiency of Cardiotropic Therapy in Neonatal Infants with Posthypoxic Myocardial Damage

Общая реаниматология, 2011
Objective: to define the optimal tranexamic acid dosage regimen to reduce perioperative blood loss during total endo-prosthetic hip joint replacement (TEHJR). Subjects and methods.
Yu. N. Belova, A. A. Tarasova, I. F. Ostreikov   +2 more
doaj   +1 more source

Peritoneal dialysis catheter dysfunction due to fibrin clots following treatment with tranexamic acid: a clinical case

Bulletin de la Dialyse à Domicile, 2021
Chronic kidney disease patients experience not only more frequent arterial and venous thrombosis but also hemorrhagic episodes. Tranexamic acid is an anti-fibrinolytic molecule that inhibits plasmin activation.
Elodie Bogner, Elodie Ferrero, Joelle Marin, Stanislas Bataille   +3 more
doaj   +1 more source

Topical use of antifibrinolytic agents reduces postoperative bleeding: a double-blind, prospective, randomized study [PDF]

, 2007
Objective: Postoperative bleeding is still one of the most common complications of cardiac surgery. Antifibrinolytic agents successfully reduce bleeding, but there are controversies concerning adverse effects after their systemic use.
Barić, Davor, Bačić Vrca, Vesna, Biočina, Bojan, Brkić, Kristina, Ivković, Mira, Rudež, Igor, Sutlić, Željko, Unić, Daniel   +7 more
core   +1 more source

Combined Nebulized and IV Tranexamic Acid for Hemoptysis Management: A Case Report and Brief Literature Review. [PDF]

Clin Case Rep
(A and B) Sections of spiral lung CT scan reveal mosaicism and bronchial wall thickening; (C) Bronchoscopic view of intermediate bronchus reveals bronchial erythema. ABSTRACT Hemoptysis management may necessitate invasive interventions, but combined nebulized and intravenous tranexamic acid (TXA) can play a promising noninvasive role in controlling ...
Ghadirzadeh E, Shokri F, Khorshidian S, Ziari A, Gheibi M, Adelani M, Salehi Mashhad Sari SP, Varshoei F, Mehravaran H.   +8 more
europepmc   +2 more sources