Results 41 to 50 of about 5,023,654 (293)

Blood-Preserving Effect of Tranexamic Acid in Knee Joint Replacement

Общая реаниматология, 2008
Objective: to evaluate the efficacy and safety of tranexamic acid in knee joint replacement. Subjects and methods: the prospective open-label study of the efficacy of tranexamic acid as an agent for blood loss reduction in knee joint replacement included
Yu. L. Shevchenko, Yu. M. Stoiko, M. N. Zamyatin, B. A. Teplykh, I. A. Karpov, D. A. Smolkin   +5 more
doaj   +1 more source

Tranexamic acid for intracerebral haemorrhage within 2 hours of onset: protocol of a phase II randomised placebo-controlled double-blind multicentre trial

Stroke and vascular neurology, 2021
Rationale Haematoma growth is common early after intracerebral haemorrhage (ICH), and is a key determinant of outcome. Tranexamic acid, a widely available antifibrinolytic agent with an excellent safety profile, may reduce haematoma growth.
N. Yassi, Henry Zhao, L. Churilov, B. Campbell, Teddy Y. Wu, Henry Ma, A. Cheung, T. Kleinig, H. Brown, P. Choi, J. Jeng, A. Ranta, Hao-kuang Wang, G. Cloud, R. Grimley, D. Shah, N. Spratt, D. Cho, K. Mahawish, L. Sanders, J. Worthington, B. Clissold, A. Meretoja, V. Yogendrakumar, M. D. Ton, Duc Phuc Dang, Nguyen Thai My Phuong, Huy-Thang Nguyen, C. Hsu, G. Sharma, P. Mitchell, B. Yan, M. Parsons, Christopher Levi, G. Donnan, S. Davis   +35 more
semanticscholar   +1 more source

THE EFFECT OF TRANEXAMIC ACID INJECTION ON HEMOGLOBIN LEVEL, ALBUMIN LEVEL, AND PAIN ON PATIENT RECEIVING TOTAL KNEE REPLACEMENT

Journal Orthopaedi and Traumatology Surabaya, 2019
Background: The high number of knee osteoarthritis cases could lead arthroplasty more frequent. Total Knee Replacement (TKR) surgery procedure is at risk of massive bleeding.
Dwikora Novembri Utomo, Teddy Heri Wardhana, Ahmad Hannan Amrullah, Hamzah Hamzah   +3 more
doaj   +1 more source

Tranexamic Acid Update in Trauma [PDF]

Critical Care Clinics, 2017
Following results from the CRASH-2 trial, tranexamic acid (TXA) gained considerable interest for the treatment of hemorrhage in trauma patients. Although TXA is effective at reducing mortality in patients presenting within 3 hours of injury, optimal dosing, timing of administration, mechanism, and pharmacokinetics require further elucidation.
Grant V. Bochicchio, Ricardo J. Ramirez, Philip C. Spinella   +2 more
openaire   +3 more sources

Periodontitis and atherosclerotic cardiovascular disease: A critical appraisal

Periodontology 2000, EarlyView., 2023
Abstract In spite of intensive research efforts driving spectacular advances in terms of prevention and treatments, cardiovascular diseases (CVDs) remain a leading health burden, accounting for 32% of all deaths (World Health Organization. “Cardiovascular Diseases (CVDs).” WHO, February 1, 2017, https://www.who.int/news‐room/fact‐sheets/detail ...
Maria Clotilde Carra, Hélène Rangé, Giuseppina Caligiuri, Philippe Bouchard   +3 more
wiley   +1 more source

Validation of the BATT score for prehospital risk stratification of traumatic haemorrhagic death: usefulness for tranexamic acid treatment criteria

Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, 2021
Background Tranexamic acid reduces surgical blood loss and reduces deaths from bleeding in trauma patients. Tranexamic acid must be given urgently, preferably by paramedics at the scene of the injury or in the ambulance.
Francois-Xavier Ageron, Timothy J. Coats, Vincent Darioli, Ian Roberts   +3 more
doaj   +1 more source

Efficacy Of Tranexamic Acid in Reducing Blood Loss in Primary Total Knee Replacement

Journal of Rawalpindi Medical College, 2023
Objective: To determine the efficacy of tranexamic acid in reducing blood loss in primary total knee replacement. Material and Methods: A total of 96 patients having a diagnosis of primary knee osteoarthritis made up the population sample.
Muhammad Inaamullah Younas, Faizan Rauf, Muhammad Sheraz Mustafa, Sarmad Nasir Janjua, Shaheen Iqbal, Khurram Habib   +5 more
doaj   +1 more source

Electrospun Fenoprofen/Polycaprolactone @ Tranexamic Acid/Hydroxyapatite Nanofibers as Orthopedic Hemostasis Dressings

Nanomaterials
Dressings with multiple functional performances (such as hemostasis, promoting regeneration, analgesia, and anti-inflammatory effects) are highly desired in orthopedic surgery.
Changfa Huang, Menglong Wang, Siyou Yu, Dengguang Yu, S. A. Bligh   +4 more
semanticscholar   +1 more source

Efficacy and safety of tranexamic acid in the treatment of adult melasma: An updated meta‐analysis of randomized controlled trials

Journal of Clinical Pharmacy and Therapeutics, 2021
Tranexamic acid (TXA) is a novel treatment option for melasma; however, no consensus exists on its use. This study evaluates the efficacy and safety of TXA for melasma.
Xiaowei Feng, H. Su, Jinwei Xie
semanticscholar   +1 more source

Tranexamic acid: a clinical review

Anestezjologia Intensywna Terapia, 2015
Blood loss and subsequent transfusions are associated with major morbidity and mortality. The use of antifibrinolytics can reduce blood loss in cardiac surgery, trauma, orthopedic surgery, liver surgery and solid organ transplantation, obstetrics and gynecology, neurosurgery and non-surgical diseases.
Angela Jerath, Marcin Wąsowicz, William C. K. Ng   +2 more
openaire   +2 more sources