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Effect of early tranexamic acid administration on mortality, hysterectomy, and other morbidities in women with post-partum haemorrhage (WOMAN): an international, randomised, double-blind, placebo-controlled trial [PDF]
, 2017 Background
Post-partum haemorrhage is the leading cause of maternal death worldwide. Early administration of tranexamic acid reduces deaths due to bleeding in trauma patients.Aasia Kayani, Abalaka Aye, Abdalla Mohammed, Abdulfetah Abdulkadir, Abdulfetah Abdulkadir, Abdulfetah Abdulkadir, Abdulrasaq Sambo, Abida Sajid, Abiodun Aboyeji, Abiodun Adeniran, Abraham Onwe, Abu Kholdun, Adebayo Adewale, Adebola Owodunni, Adeniyi Fasanu, Adesina Akintan, Adesina Akintan, Adetunji Adeniji, Adeyemi Okunowo, Ado Geidam, Adolphe Somé, Adrian Grant, Aferdita Kruja, Affiss Adelodun, Afshan Batool, Ahmad Kazumari, Aisha Iftikhar, Ajay Agrawal, Akhtar Sherin, Akintunde Ayinde, Akpojaro Ikpen, Alex Nyakundi Bosire, Alexander Kawimbe, Alfred Osoti, Alia Bano, Alice Ashu, Alice Ntem, Alison Bates, Alysha Allibone, Amadou Ly, Amadou Ndouoya, Amaitari Bariweni, Ambreen Ikram, Amos Otara, Amtullah Zarreen, Andrea Jogo, Andrew Sharpe, André Simo, Angeline Njoache, Aniefiok Umoiyoho, Anita Ali, Anna Danford, Anthony Kwame Dah, Anthony Massinde, Antony Wanjala, Arafat Ifemeje, Armida Tola, Asia Nazir, Asma Baloch, Audu Idrisa, Augustine Adeniyi, Austin Ojo, Awadia Ali, Ayesha Mobeen, Ayiko Jackson, Babalola Adeyemi, Babalola Adeyemi, Babasola Okusanya, Babatunde Adebudo, Babatunde Awolaja, Badibanga Musau, Bamidele Adeleye, Bartthy Okorochukwu, Basharat Ahmad, Bellington Vwalika, Bellington Vwalika, Bellington Vwalika, Bernadette Nakawooya Lwasa, Berno Mwambe, Besnik Brahimaj, Beverley Hunt, Bhola Ram Shrestha, Blessed Adeyemi, Bonface Musila, Brian Liyayi, Brigadier Naila, Bukola Fawole, Bukola Fawole, Bukola Fawole, Carine Ronsmans, Carine Ronsmans, Carroli, Carys Smith, Catherine Gilliam, Cesar Sanchez, Chapman, Charles Kacha, Chris Aimakhu, Christine Biryabarema, Christine Namulwasira, Christine Nanyongo, Chrstine Biryabarema, Clare Tower, Collette Barrow, Dachollom Audu, Daniel Gilbert, Daniel Onwusulu, Danielle Beaumont, Danielle Beaumont, Danielle Prowse, David Isah, Dawn Edmundson, Desire Tshombe, Dewan, Diana Elbourne, Dominic Drametu, Dorothy Keka, Ducloy-Bouthors, Duria Rayis, Egbaname Aigere, Elhassan Safa, Elizabeth Buligho, Elizabeth Ndagire, Elizabeth Nionzima, Emily Nzeribe, Emmanuel Byaruhanga, Emmanuel Gbejegbe, Emmanuel Inyang-Etoh, Emmanuel Okpako, Eni Balogun, Enyinnaya Chikwendu Nduka, Eta Ngole Mbong, Etienne Asonganyi, Etienne Asonganyi, Eugene Oteng-Ntim, Evelyn Muthoka, Ezekiel Ladan, Eziamaka Pauline Ezenkwele, Ezukwa Omoronyia, Faiza Aleem, Faiza Nassir, Fareesa Waqar, Farjana Basher, Faryal Sardar, Farzana Burki, Fatimah Habeebu-Adeyemi, Fehmida Shaheen, Felix Okogbo, Ferdousi Chowdhury, Ferdousi Islam, Fikre Geremew, Folasade Oyelade, Fouzia Gul, Francis Alu, Francis Banya, Gabriel Essetchi Faye, George Bugg, George Mtove, Georges Nko'ayissi, Getachew Ayana, Ghazala Taj, Gilda Piaggio, Gillian Houghton, Gladys Dibia, Glen Mola, Grace Adekola-Oni, Grace Akinbinu, Grace Meregurwa, Gulfareen Arain, Gyanendra Karki, Habiba Sharaf Ali, Hadia Mustafa, Hadiza Galadanci, Hadiza Idris, Hailemariam Segni, Hajaratu Sulayman, Hajira Masood, Hakim Miah, Hala Abdullahi, Haleema Hashmi, Haleema Shakur, Haleema Shakur, Haleema Shakur, Hassen Hussien, Henry Mwangi, Henry Opare-Addo, Herman Kalyana, Hillary Mabeya, Hina Rajani, Horace Fletcher, Huida Almardi, Huida Eltaib, Huma Quddusi, Hussein Iman, Hussein Khamis, Hussein Kidanto, Hussein Kidanto, Hussein Kidanto, Iain Chalmers, Ian Roberts, Ian Roberts, Ian Roberts, Ian Roberts, Ibrahim Habib, Ifeoma Offiah, Ikemefuna Nwosu, Ilir Tasha, Isabirye Rebecca, Isaiah Hansingo, Jacob Awoleke, Jane Mumba, Jean Robert Lubamba, Jeanne Fouedjio, Jeharat Gul, Jim Thornton, Joanne Wilkins, John Ogudu, Joselyn Ayikoru, Joseph Agulebe, Joseph Ikechebelu, Joseph Ngonzi, Josiah Mutihir, Kamil Shoretire, Kaosar Afsana, Kastriot Dallaku, Kastriot Dallaku, Kato Faida, Kayode Olayinka, Kayode Oluwatosin, Kehinde Ologunde, Kenfack Bruno, Ker, Ker, Khadija Mayumba, Khalid Elfadl, Khidir Awadalla, Kim Hinshaw, Kiran Jabeen, Kiran Javaid, Kruithof, Kubasu Wekesa, Kusasira Anitah, Kwadwo Nyarko-Jectey, Lamaran Dattijo, Lauren Frimley, Lawrence Omo-Aghoja, Lema Felix, Leon Kaza, Leonard Madame, Leslie Samuels, Liliana Vallecilla, Lin Barneston, Lisa Cook, Lubna Bashir, Lubna Dar, Lubna Kahloon, Lucky Oyeye, Magdy El Rahman, Magreth Zacharia, Mahdi Bushra, Mahwish Jamil, Maimoona Hafeez, Maimoona Munawar, Maliha Zafar, Malts Wai, Manahil Jaffer, Margret Nankya, Maria Fernanda Escobar, Maria Ramos, Mariam Tariq, Mark Ogbiti, Martin Saadio, Mateus Sahani, Mateus Sahani, Mathew Ng'ambi, Matilda Ngarina, Mesack Tchana, Metin Gülmezoglu, Metin Gülmezoglu, Misbah Harim, Mohamed Ahmed, Mohamed El-Sheikh, Mohamed El-Sheikh, Mohammed Gana, Mohammed Musa, Mohan Regmi, Mohan Regmi, Mohd Chohan, Moses Alao, Moussa Bambara, Murwan Ibrahim, Musarrat Jabeen, Musimbi Soita, Muzdalifat Abeid, Mwansa Ketty Lubeya, Mwansa Lubeya, Myles, Nabia Tariq, Nabila Salman, Nadia Sadiq, Naila Israr, Naila Israr, Nakirigya Nuulu, Nankat Joseph, Naseem Saba, Naseema Usman, Nasira Tasnim, Nayiga Annet, Nazlima Nargis, Nazneen Begum, Neelam Surhio, Nick Grace, Nicolas Meda, Nigel Quashi, Nighat Shaheen, Nike Bello, Nikita Dhakal, Nilofar Mustafa, Nishat Akram, Nji Eric, Nkeiruka Ameh, Nkonwa Innocent, Nneka Madueke, Noah Olaomo, Noojiri Bopili, Noonari Mukhtiar, Nurudeen Onaolapo, Nzanzu Kikuhe Jason, Odel Gwan, Odidika Umeora, Okpe James, Ola Nene Okike, Ola Okike, Olabisi Loto, Oladapo, Oladapo Olayemi, Oladapo Olayemi, Olaide Salau, Olalekan Awonuga, Olatunde Onafowokan, Olubunmi Ladipo, Olufemi Abidoye, Olufemi Akinsanya, Olufemi Odekunle, Olugbenga Akintunde, Olujide Okunade, Olusade Adetayo, Olusegun Ajenifuja, Oluseyi Adelekan, Oluwabusola Monehin, Oluwarotimi Akinola, Oluwaseun Adeyemi, Omer Babiker, Omololu Adegbola, Onyebuchi Udegbunam, Osagie Osayande, Owigho Opreh, Palmer Henry, Pascal Foumane, Patrick Komagum, Paul Ayuk, Paul Kua, Pauline Assomo, Peninah Waigi, Peter Achara, Phanny Simisi, Phil Edwards, Philemon Nsem, Pierre Marie Tebeu, Pisake Lumbiganon, Pramila Pradhan, Prieto-Merino, Punita Yadav, Pushpa Sachdev, Qurratul Ain, Rabia Batool, Rabindra Bhatt, Raheela Asmat, Rashida Sultana, Razia Khero, Regina Akello, Riffat Shaheen, Riham Desougi, Rita Atim, Rizwana Chaudhri, Rizwana Chaudhri, Rizwana Chaudhri, Rizwana Chaudhri, Roamba Pabakba, Rob Jackson, Robert Tchounzou, Robert Tchounzou, Roberts, Roderick Larsen-Reindorf, Roger Paluku-Hamuli, Rokeya Begum, Ronsmans, Rophina Msengeti, Rose Bwotya, Rose Wangui, Roseline Iheagwam, Roshan Qazi, Rubina Hussain, Rubina Sohail, Rukhsana Karim, Ruth Bulime, Rwakyendela Onesmo, Saba Javed, Sabaratnam Arulkumaran, Sadaf Mufti, Sadaqat Jabeen, Sadia Khan, Saeed Abdelrahman Abdelgabar, Saeeda Majeed, Safia Khalil, Saima Iqbal, Saimir Cenameri, Saira Dars, Sajila Karim, Salma Khudaidad, Samana Aleem, Samar Amin, Samina Dojki, Samina Iqbal, Samina Kausar, Samina Manzoor, Samirra Ahmed, Sanobar Ashfaq, Sara Saeed, Sarah Babirye, Saturday Etuk, Saturday Etuk, Sawamura, Say, Sayeba Akhter, Sayeba Akhter, Sebastian Kitengile Ganyaka, Serge Mulyumba, Sergey Kostrov, Shabana Rizvi, Shabween Masood, Shah, Shahela Jesmin, Shahenzad Sohail, Shahid Rao, Shakur, Shakur, Shama Chaudhry, Shamayela Hanif, Shamsa Humayun, Shamsunnisa Sadia, Sharmeen Arshad, Shazia Batool, Shazia Rasul, Shazia Sultana, Shehla Manzoor, Shehla Noor, Shehla Noor, Shrodha Paul, Shyam Gupta, Simeon Bazuaye, Sofia Manzoor, Sola Abubakar, Somia Abdelrahiem, Sophia Udonwa, Sumaya Huque, Summera Aslam, Sununu Yusuf, Swati Singh, Syeda Mazhar, Syeda Rabia Bukhari, Taemi Kawahara, Taha Umbeli, Tahir Kyani, Tahira Batool, Tasneem Ashraf, Tayyiba Wasim, Temitope Onile, Theresa Azonima Irinyenikan, Tom Godec, Tony Brady, Tort, Tracey Pepple, Ubong Akpan, Uduak Udofia, Umar Ibrahim, Umbreen Akram, Useneno Okon, Uzma Shaheen, Venantius Mutsu, Veronicah Ongwae, Victor Wanjohi, Vincent Oyiengo, Wafaa Basta, Willard Mtambo, William Golit, William Haleke, Willies Silwimba, Willis Missumba, Wisal Nabag, Wu, Yinka Amode, Ymele Fouelifack, Yusuf Baffah Adamu, Zahida Qureshi, Zahida Qureshi, Zahida Qureshi, Zarko Alfirevic, Zarko Alfirevic, Zarko Alfirevic, Zeinab Zubier, Ziche Makukula +511 morecore +3 more sourcesTranexamic acid-induced fixed drug eruption
Indian Journal of Dermatology, 2015 A 33-year-old male showed multiple pigmented patches on his trunk and extremities after he took tranexamic acid for common cold. He stated that similar eruptions appeared when he was treated with tranexamic acid for influenza 10 months before. Patch test Natsuko Matsumura, Yuka Hanami, Toshiyuki Yamamoto +2 moredoaj +1 more sourceBlood-Preserving Effect of Tranexamic Acid in Knee Joint Replacement
Общая реаниматология, 2008 Objective: to evaluate the efficacy and safety of tranexamic acid in knee joint replacement. Subjects and methods: the prospective open-label study of the efficacy of tranexamic acid as an agent for blood loss reduction in knee joint replacement included Yu. L. Shevchenko, Yu. M. Stoiko, M. N. Zamyatin, B. A. Teplykh, I. A. Karpov, D. A. Smolkin +5 moredoaj +1 more sourceEffect of Out-of-Hospital Tranexamic Acid vs Placebo on 6-Month Functional Neurologic Outcomes in Patients With Moderate or Severe Traumatic Brain Injury.
Journal of the American Medical Association (JAMA), 2020 Importance
Traumatic brain injury (TBI) is the leading cause of death and disability due to trauma. Early administration of tranexamic acid may benefit patients with TBI.Susan E. Rowell, Susan E. Rowell, E. Meier, B. McKnight, Delores Kannas, S. May, Kellie L. Sheehan, E. Bulger, A. Idris, J. Christenson, J. Christenson, L. Morrison, L. Morrison, R. Frascone, Patrick L. Bosarge, Patrick L. Bosarge, M. Colella, J. Johannigman, B. Cotton, J. Callum, J. McMullan, D. Dries, B. Tibbs, N. Richmond, M. Weisfeldt, J. Tallon, J. Garrett, M. Zielinski, T. Aufderheide, R. Gandhi, R. Schlamp, B. Robinson, J. Jui, L. Klein, S. Rizoli, Mark A. Gamber, Michael Fleming, Jun-Wan Hwang, Laura E. Vincent, Carolyn R. Williams, Audrey Hendrickson, R. Simonson, Patricia Klotz, G. Sopko, William R. Witham, Michael J. Ferrara, M. Schreiber +46 moresemanticscholar +1 more sourceSafety and Efficacy of Hospital Utilization of Tranexamic Acid in Civilian Adult Trauma Resuscitation [PDF]
, 2020 Introduction: Patients with trauma-induced coagulopathies may benefit from the use of antifibrinolytic agents, such as tranexamic acid (TXA). This study evaluated the safety and efficacy of TXA in civilian adults hospitalized with traumatic hemorrhagic ...Borger, Rodney, Chandwani, Deepak, Comunale, Mark E., Dong, Fanglong, Inaba, Kenji, Lowe, Andrew, Neeki, Michael, Powell, Joe, Quispe, Juan, Rabiei, Massoud, Salameh, Joseph, Toy, Jake, Vara, Richard, Wong, David +13 morecore Management of severe epistaxis during pregnancy: a case report and review of the literature [PDF]
, 2019 Epistaxis is a common problem during pregnancy. Few cases of severe epistaxis, not associated with nasal lesions or clotting disorders, were described in the literature.Brunelli, Roberto, Derme, Martina, Morrocchi, Elisa, Pecorini, Francesco, Piccioni, Maria Grazia, Porpora, Maria Grazia, Salerno, Laura +6 morecore +1 more source
