Results 61 to 70 of about 26,721 (231)

Efficacy and Safety of Tranexamic Acid in Melasma: A Meta-analysis and Systematic Review

Acta Dermato-Venereologica, 2017
Tranexamic acid is a novel treatment option for melasma; however, there is no consensus on its use. This systematic review searched major databases for relevant publications to March 2016. Eleven studies with 667 participants were included.
Hyun Jung Kim, Seok Hoon Moon, Sang Hyun Cho, Jeong Deuk Lee, Hei Sung Kim   +4 more
doaj   +1 more source

Prevention of haematoma progression by tranexamic acid in intracerebral haemorrhage patients with and without spot sign on admission scan: a statistical analysis plan of a pre-specified sub-study of the TICH-2 trial

BMC Research Notes, 2018
Objective We present the statistical analysis plan of a prespecified Tranexamic Acid for Hyperacute Primary Intracerebral Haemorrhage (TICH)-2 sub-study aiming to investigate, if tranexamic acid has a different effect in intracerebral haemorrhage ...
Christian Ovesen, Janus Christian Jakobsen, Christian Gluud, Thorsten Steiner, Zhe Law, Katie Flaherty, Rob A. Dineen, Philip M. Bath, Nikola Sprigg, Hanne Christensen   +9 more
doaj   +1 more source

Retropubic hemorrhage following Midurethral sling surgery: Diagnosis, clinical challenges, and management

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
Retropubic hemorrhage after TVT surgery, though rare, is a serious complication—we outline a management strategy emphasizing timely diagnosis and tailored treatment to reduce morbidity. Abstract Mid‐urethral slings (MUS) such as tension‐free vaginal tape (TVT) are the established gold standard surgical approach for treating stress urinary incontinence (
Greta Lisa Carlin, Christina Tanja Grech, Wolfgang Umek, Engelbert Hanzal, Marianne Koch, Barbara Bodner‐Adler   +5 more
wiley   +1 more source

Current gynaecological management of women and girls with bleeding disorders in the United Kingdom: A UKHCDO haemophilia treatment centre survey and evaluation of real‐world clinical practice for the British Journal of Haematology

British Journal of Haematology, EarlyView.
Summary Girls and women with bleeding disorders (GWBD) comprise more than half of all registered patients with bleeding disorders in the UK National Haemophilia Database. The gynaecological care of GWBD, until recently, has not been prioritised despite high health burdens, where four of every five patients experience heavy menstrual bleeding (HMB).
Laura Knox, Imogen Swart‐Rimmer, Naim Rahimi, Callum Harris, Lugain Abdalla, Gary Benson, Clare Brown, Helen Campbell, Ana Carvalhosa, Justin T. Clarke, Sarah Garside, Claire Lentaigne, Jayna Mistry, Priyanka Raheja, Cora Warren, Rezan Abdul‐Kadir, Gill Lowe, Nicola Curry   +17 more
wiley   +1 more source

Medical haematology: Repositioning haematology at the centre of medicine

British Journal of Haematology, EarlyView.
The complementary domains of Medical Haematology and Haemato‐Oncology share a biological framework. The left panel depicts red cells, platelets, coagulation, thrombosis and innate immunity, while the right panel shows lymphoid and myeloid malignancies.
Cheng Hock Toh, Imelda Bates, Sue Pavord
wiley   +1 more source

DOES TRANEXAMIC ACID REDUCE BLOOD LOSS IN OFF-PUMP CORONARY ARTERY BYPASS? [PDF]

Acta Medica Iranica, 2006
Tranexamic acid is now used on a routine basis for on-pump coronary artery bypass grafting (CABG). We assessed the hemostatic effects of tranexamic acid to decrease bleeding tendency and transfusion requirements in patients undergoing off-pump coronary ...
A. Mehr-Aein, M. Sadeghi M. Madani-Civi   +1 more
doaj   +1 more source

The role of 5‐alpha reductase inhibitors in transurethral resection of the prostate: a meta‐analysis of randomised controlled trials

BJU International, EarlyView.
Objective To critically evaluate the existing evidence base surrounding the efficacy of preoperative 5‐alpha reductase inhibitor (5ARI) administration in the reduction of perioperative complication rates in transurethral resection of prostate (TURP). Methods In April 2025, a systematic search of on‐line databases was conducted to identify randomised ...
Cian M. Hehir, Gavin G. Calpin, Orla Cullivan, Gordon R. Daly, Gavin P. Dowling, Niall F. Davis   +5 more
wiley   +1 more source

Novel Histopathologic Features of Diffuse Blue‐Gray Hyperpigmentation Associated With Kratom Use: A Case Report and Literature Review

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT Background Drug‐induced hyperpigmentation accounts for 10%–20% of acquired pigmentary disorders and can be misdiagnosed for other causes such as melasma, post inflammatory changes, or heavy metal deposition. Kratom (Mitragyna speciosa), a Southeast Asian plant with an opioid‐like profile, has been increasingly used in the United States for ...
Rita Kamoua, Kristen Paradine, Craig A. Rohan, Mary McDaniel, Diane Perkins   +4 more
wiley   +1 more source

Interstitial 11q Deletions and Terminal 11q Duplications Cause a Bleeding Tendency due to Platelet Dysfunction That Is Similar to 11q Deletions Causing Jacobsen Syndrome

European Journal of Haematology, EarlyView.
ABSTRACT Introduction Jacobsen syndrome, resulting from a terminal deletion of chromosome 11 (11q), may lead to an increased bleeding tendency due to low platelet counts or platelet dysfunction. Currently, information on bleeding tendency and platelet function in patients with nonterminal 11q‐aberrations such as larger deletions, interstitial 11q ...
Elise J. Huisman, Virgil A. S. H. Dalm, Marieke Joosten, Frans J. Smiers, Leendert Porcelijn, Arjan Hoogendijk, Hans Janssen, Nicole N. van der van der Wel, Idske C. L. Kremer Hovinga, Masja de Haas, Marjon H. Cnossen   +10 more
wiley   +1 more source

Efficacy of tranexamic acid in reducing blood loss in posterior lumbar spine surgery for degenerative spinal stenosis with instability: a retrospective case control study

BMC Surgery, 2011
Background Degenerative spinal stenosis and instability requiring multilevel spine surgery has been associated with large blood losses. Factors that affect perioperative blood loss include time of surgery, surgical procedure, patient height, combined ...
Endres Stefan, Heinz Martin, Wilke Axel
doaj   +1 more source