Results 211 to 220 of about 897,116 (253)
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Transcriptional trans-activating function of hepatitis B virus

Journal of Virology, 1987
The ability of hepatitis B virus (HBV) to stimulate the expression of a cellular gene was investigated by using a transient-expression system. A plasmid in which the expression of the bacterial chloramphenicol acetyltransferase (cat) gene had been placed under the control of the DNA sequences that regulate the expression of the human beta-interferon ...
J S, Twu, R H, Schloemer
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New insights into the mechanism of HIV-1 trans-activation

Trends in Genetics, 1992
acting factors were found sub- sequently in all other lentiviruses, including HIV-2 and simian im- munodeficiency virus (SIV). These findings stimulated intensive re- search into the mechanism of action of Tat and a search for antiviral compounds 1. Now, nearly seven years later, a coherent pic- ture of how Tat works is emerging. Transcription from the
J, Karn, M A, Graeble
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A cytosolic trans-activation domain essential for ammonium uptake

Nature, 2007
Polytopic membrane proteins are essential for cellular uptake and release of nutrients. To prevent toxic accumulation, rapid shut-off mechanisms are required. Here we show that the soluble cytosolic carboxy terminus of an oligomeric ammonium transporter from Arabidopsis thaliana serves as an allosteric regulator essential for function; mutations in the
D, Loqué   +4 more
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A Quantitative Bioassay for HIV-1 Based on Trans-Activation

Science, 1988
A bioassay that is based on trans-activation has been developed for the detection and quantitation of the human immunodeficiency virus type 1 (HIV-1). Indicator cell lines were constructed that contain the HIV-1 long terminal repeat ligated to the chloramphenicol acetyltransferase (CAT) gene.
B K, Felber, G N, Pavlakis
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Mechanisms of Viral-Mediated Trans-Activation of Transcription

1989
Publisher Summary This chapter discusses the features and characteristics of the E1A trans-activation system besides the related details deriving from other relevant viral systems. The studies of herpes virus trans-activation have provided many details both unique and similar to the E1A system.
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[Viral transcription trans-activators].

Biokhimiia (Moscow, Russia), 1994
The structure and functional peculiarities of a wide range of viral transcriptional transactivators have been considered. Analysis of literature data, concerning with the principles of functioning has made it possible to divide the viral transcriptional transactivators into three major groups: transcriptional transactivators of large DNA-containing ...
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