Results 271 to 280 of about 56,323 (331)

Identification of the trans-acting factors controlling expression of SbMATE, an aluminum-activated citrate transporter that underlies aluminum tolerance in sorghum. [PDF]

, 2013
Júlio Onésio Ferreira Melo, U. G. P. Lana, C. T. Guimarães, R. W. Noda, J. Liu, Leon V. Kochian, S. E. Mitchell, Zhaoxiong Fei, Veridiana S. P. Cano, R. E. Schaffert, J. V. de Magalhães   +10 more
openalex  

Innentitelbild: A Sensitive Technique Unravels the Kinetics of Activation and Trans ‐Cleavage of CRISPR‐Cas Systems (Angew. Chem. 22/2024) [PDF]

Wei Feng, Hanyong Peng, Hongquan Zhang, Michael Weinfeld, X. Chris Le   +4 more
openalex   +1 more source

Mammalian Proteome Profiling Reveals Readers and Antireaders of Strand‐Symmetric and ‐Asymmetric 5‐Hydroxymethylcytosine‐Modifications in DNA

Advanced Science, EarlyView.
We investigate by proteomics studies how strand‐symmetric and ‐asymmetric cytosine 5‐modifications in DNA are selectively recognized by the nuclear proteome. Using promoter probes with defined modification patterns, we identify tissue‐specific reader proteinsincluding MYC, MAX, and RFX5that discriminate 5‐hydroxymethylcytosine symmetry and sequence ...
Lena Engelhard, Zeyneb Vildan Cakil, Marlon S. Zambrano‐Mila, Simone Eppmann, Tye Gonzalez, Rasmus Linser, Petra Janning, Sidney Becker, Daniel Summerer   +8 more
wiley   +1 more source

Organic acid-mediated phosphorus mobilization in black soils: differential effects of maize root exudates on alfisols and mollisols in Northeast China. [PDF]

PLoS One
Zhao W, Zhang Y, Xie X, Li H, Zhang J.
europepmc   +1 more source

A dsRNA Viral Transcriptional Regulator Evades Innate Immunity by Hijacking Host CoTranscription Factor DHX9

Advanced Science, EarlyView.
This study identifies a new viral mechanism by a viral protein σ3 that functions as a vTR to suppress NF‐κB gene expression via its direct interaction with the host helicase DHX9. Through their interaction, σ3 not only impairs the initial recruitment of Pol II but also affects Pol II pause‐release and ultimately suppresses NF‐κB gene expression ...
Xueyang Pang, Shiyu Liu, Yixiao Zhu, Meleana M. Hinchman, Nan Qiao, Xuejun Li, Weiqian Dai, Yingying Tong, Man Xing, Jiling Ren, John S. L. Parker, Yingying Guo, Dongming Zhou   +12 more
wiley   +1 more source

Direct Interleukin-6 Inhibition Blunts Arterial Thrombosis by Reducing Collagen-Mediated Platelet Activation. [PDF]

Arterioscler Thromb Vasc Biol
Ministrini S, Liberale L, Puspitasari YM, Han J, Kirmes K, Unkelbach LP, Tirandi A, Niederberger R, Bengs S, Beer JH, Montecucco F, Libby P, Lüscher TF, Bongiovanni D, Camici GG.   +14 more
europepmc   +1 more source

Molecular Mechanism of Rev/Rex-Dependent Trans-Activation of Viral Genes (RESEARCH FACILITY OF NUCLEIC ACIDS)

, 1996
Yoshifumi Adachi
openalex   +1 more source

The Mitochondrial Guardian α‐Amyrin Mitigates Alzheimer's Disease Pathology via Modulation of the DLK‐SARM1‐ULK1 Axis

Advanced Science, EarlyView.
Dietary habits play a key role in chronic diseases, and higher annual consumption of fruit and vegetable may lower risk of dementia. Artificial intelligence predicts the lipid‐like compound α‐Amyrin (αA) from plants with edible peels as a drug candidate against Alzheimer's disease.
Shu‐Qin Cao, Juan Ignacio Jiménez‐Loygorri, Yunguang Qiu, You Jung Kang, Khanh Van Do, Annabel E. Smith, Junjie Huang, Jun‐ping Pan, Lipeng Mao, Ang Li, Hangge Yang, Yahyah Aman, Maria Jose Donate Lagartos, Sofie Hindkjær Lautrup, Anbin Chen, Kristina Xiao Liang, Hailong Zhang, Juan Yi, Xurui Jin, Tin Cho Cheung, Olympia Apokotou, Florentia Papastefanaki, Rebecca Matsas, William A. McEwan, Feixiong Cheng, Hansang Cho, Guobing Chen, Huanxing Su, Konstantinos Palikaras, Oscar Junhong Luo, Qian Hua Zhao, Ding Ding, Cornelia van Duijn, Nektarios Tavernarakis, Patricia Boya, Tewin Tencomnao, Evandro F. Fang   +36 more
wiley   +1 more source

Ultrasensitive detection of clinical pathogens through a target-amplification-free collateral-cleavage-enhancing CRISPR-CasΦ tool. [PDF]

Nat Commun
Chen H, Song F, Wang B, Huang H, Luo Y, Han X, He H, Lin S, Wan L, Huang Z, Fu Z, Ledesma-Amaro R, Yin D, Mao H, He L, Yang T, Chen Z, Ma Y, Xue EY, Wan Y, Mao C.   +20 more
europepmc   +1 more source

PBRM1 Deficiency Reshapes an Immune Suppressive Microenvironment Through Epigenetic Tuning of PBRM1‐KDM5C‐IL6 Axis in ccRCC

Advanced Science, EarlyView.
PBRM1 ranks as the second most commonly mutated gene in ccRCC. This study reveals that PBRM1 loss promotes an immunosuppressive microenvironment by elevating M2 TAMs via the KDM5C–IL‐6 axis. These M2 TAMs, along with CAFs, form a barrier that excludes CD8+ T cells. Targeting IL‐6 synergizes with anti‐PD1 therapy, offering a promising strategy for PBRM1‐
Wenjiao Xia, Hongru Wang, Yu Dong, Zitong Yang, Yiyang Zhou, Zhinan Xia, Qinchen Li, Liangliang Ren, Yichun Zheng, Junliang Yan, Dongmei Ma, Zhi Chen, Xingang Cui, Guixin Zhu, Cheng Zhang   +14 more
wiley   +1 more source