Results 181 to 190 of about 6,216 (203)

Clay-catalysed solventless synthesis of trans-chalcones

Green Chemistry, 2001
trans-Chalcones have been obtained in good yields and selectivities following an environmentally friendly methodology by using montmorillonite KSF as a reusable heterogeneous catalyst.
Ballini R., Bosica G., Maggi R., Ricciutelli M., Righi P., Sartori G., Sartorio R.   +6 more
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Two Nitro-α-methoxy-trans-chalcones

Acta Crystallographica Section C Crystal Structure Communications, 1996
The crystal structures of 2-methoxy-3-(3-nitrophenyl)-1-phenylprop-2-en-1-one, C16H13NO4, (Ia), and 2-methoxy-3-(2-nitrophenyl)-1-phenylprop-2-en-1-one, C16H13NO4, (Ib), are reported. These two molecules are constitutional isomers differing in the position of the nitro group attached to one of the phenyl rings.
M. Bolte, G. Schütz, H. J. Bader
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Circular dichroism spectra of trans-chalcone epoxides

Tetrahedron: Asymmetry, 2007
Abstract The electronic absorption and CD spectra of (−)- trans -chalcone epoxide and its derivatives with methyl and alkoxy substituents at the ortho -positions of the aromatic rings have been measured. The spectra have been assigned with help of the energies, oscillatory strengths, and rotatory strengths of the singlet transitions obtained from ...
Krisztina Pál, Mihály Kállay, Miklós Kubinyi, Péter Bakó, Attila Makó   +4 more
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Abstract 4654: Antitumorigenic activity of trans-chalcone in osteosarcoma

Cancer Research, 2015
Abstract Background and Aims: Osteosarcoma is the most common bone cancer, and it affects mostly teenagers and children. Although the emergence of multidrug therapies has improved available treatments for osteosarcoma, approximately 30% of patients will still develop metastasis.
Gabriel da Silva, Mozart Marins, Ana Lúcia Fachin, Seung J. Baek   +3 more
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Electronic absorption spectra of heterocyclic analogs of trans-chalcone

Chemistry of Heterocyclic Compounds, 1977
Thiophene, furan, and pyrrole analogs of trans-chalcone have UV spectra consisting of bands belonging to the spectra of the corresponding 2-acetylhetaryls and 2-hetarylideneacetones that are shifted bathochromically as a result of mutual perturbation of these two crossconjugated fragments.
M. Reinkhardt, A. A. Sukhorukov, A. Raushal', V. F. Lavrushin   +3 more
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Trans-chalcone: a novel small molecule inhibitor of mammalian alpha-amylase

Molecular Biology Reports, 2010
Trans-chalcone (1,3-diphenyl-2-propen-1-one), a biphenolic core structure of flavonoids precursor was tested for inhibitory activity toward alpha-amylase. Porcine pancreatic alpha-amylase was observed to be effectively inhibited by this compound, which showed competitive behavior with a K(i) of 48 μM. Soluble starch (the natural substrate of the enzyme)
Mahmoud, Najafian, Azadeh, Ebrahim-Habibi, Nastaran, Hezareh, Parichehreh, Yaghmaei, Kazem, Parivar, Bagher, Larijani   +5 more
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Trans-Chalcone prevents VEGF expression and retinal neovascularization in the ischemic retina

Experimental Eye Research, 2011
Retinal neovascularization (RNV) is a critical pathological event and a major cause of blindness. Vascular inflammation and oxidative stress have been shown to play a key role in the induction and progression of RNV. Trans-Chalcone-derived flavonoids have been previously shown to be negative modulators of oxidative stress and inflammatory responses as ...
Folami, Lamoke, Mohamed, Labazi, Annalisa, Montemari, Giovanni, Parisi, Monica, Varano, Manuela, Bartoli   +5 more
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Polycaprolactone/epoxide-functionalized silica composite microparticles for long-term controlled release of trans-chalcone

Journal of Polymer Engineering, 2022
Abstract In this study, controlled release of trans-chalcone was achieved by using a polycaprolactone-based hybrid system as the drug carrier material. Encapsulation efficiency was obtained in the range of 70–75% for various formulations and in vitro release studies, conducted at 37 °C and pH 7.4, revealed slow profile reaching 60 ...
Yasemin Kaptan, Yüksel Güvenilir
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Chemical sensing of chalcones by voltammetry: trans-Chalcone, cardamonin and xanthohumol

Electrochimica Acta, 2013
Abstract Xanthohumol (XN) and cardamonin (CD) belong to the chemical class of chalcones which are phenolic compounds of large interest due to their health promoting properties. In the present work, their electrochemical behavior on a hanging mercury drop electrode (HMDE) is compared to trans -chalcone by means of cyclic voltammetry (CV).
Tavares, E.M., Carvalho, A.M., Gonçalves, Luis M., Valente, I.M., Moreira, M.M., Guido, L.F., Rodrigues, J.A., Doneux, Thomas, Barros, Aquiles   +8 more
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Development of trans-Chalcone loaded pectin/casein biodegradable microcapsules: Efficacy improvement in the management of experimental colitis

International Journal of Pharmaceutics, 2023
Improved therapies for inflammatory bowel diseases are sorely needed. Novel therapeutic agents and the development of controlled release systems for targeted tissue delivery are interesting approaches to overcome these barriers. We investigated the activity of trans-chalcone (T) in acetic acid-induced colitis in mice and developed, characterized, and ...
Carla F.S. Guazelli, Victor Fattori, Barbara B. Colombo, Isabela S. Ludwig, Laisa G. Vicente, Renata M. Martinez, Sandra R. Georgetti, Alexandre Urbano, Rubia Casagrande, Marcela M. Baracat, Waldiceu A. Verri   +10 more
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