Results 1 to 10 of about 85,108 (136)
Phosphoinositide-mediated clathrin adaptor progression at the trans-Golgi network. [PDF]
Nature Cell Biology, 2012 Clathrin-coated vesicles mediate endocytosis and transport between the trans-Golgi network (TGN) and endosomes in eukaryotic cells. Clathrin adaptors play central roles in coat assembly, interacting with clathrin, cargo and membranes.
Costaguta, Giancarlo +2 more
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The link between the trans-Golgi network and tumour progression. [PDF]
Mol Biol RepAbstract The trans-Golgi network is a major sorting organelle consisting of a tubular membrane originating from the trans-Golgi cisternae. Proteins and lipids synthesised in the endoplasmic reticulum are transported through the Golgi apparatus and sorted in the trans-Golgi network into pleomorphic transport carriers targeted for various ...
Jahangiri L.
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RAB GTPases and SNAREs at the trans-Golgi network in plants. [PDF]
J Plant Res, 2022 AbstractMembrane traffic is a fundamental cellular system to exchange proteins and membrane lipids among single membrane-bound organelles or between an organelle and the plasma membrane in order to keep integrity of the endomembrane system. RAB GTPases and SNARE proteins, the key regulators of membrane traffic, are conserved broadly among eukaryotic ...
Ito E, Uemura T.
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The sorting of cargo proteins in the plant trans-Golgi network. [PDF]
Front Plant Sci, 2022 Membrane trafficking contributes to distinct protein compositions of organelles and is essential for proper organellar maintenance and functions. The trans-Golgi network (TGN) acts as a sorting station where various cargo proteins are sorted and directed to post-Golgi compartments, such as the multivesicular body or pre-vacuolar compartment, vacuoles ...
Shimizu Y, Uemura T.
europepmc +4 more sources
Lipid-dependent coupling of secretory cargo sorting and trafficking at the trans-Golgi network. [PDF]
FEBS Lett, 2019 In eukaryotic cells, the trans-Golgi network (TGN) serves as a platform for secretory cargo sorting and trafficking. In recent years, it has become evident that a complex network of lipid-lipid and lipid-protein interactions contributes to these key ...
von Blume J, Hausser A.
europepmc +2 more sources
Trans-Golgi network sorting [PDF]
Cellular and Molecular Life Sciences, 2001 The trans-Golgi network (TGN) is a major secretory pathway sorting station that directs newly synthesized proteins to different subcellular destinations. The TGN also receives extracellular materials and recycled molecules from endocytic compartments.
F, Gu, C M, Crump, G, Thomas
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From endosomes to the trans-Golgi network [PDF]
Seminars in Cell & Developmental Biology, 2014 The retrograde trafficking from endosomes to the trans-Golgi network (TGN) is one of the major endocytic pathways to divert proteins and lipids away from lysosomal degradation. Retrograde transported cargos enter the TGN via two itineraries from either the early endosome/recycling endosome or the late endosome and involve various machinery components ...
Lu, Lei, Hong, Wanjin
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CLASPing Microtubules at the trans-Golgi Network [PDF]
Developmental Cell, 2007 Microtubule (MT) arrays can be formed either from centrosomes or from noncentrosomal locations. In this issue of Developmental Cell, Efimov and colleagues report a role of CLASPs, the MT plus end-binding proteins, in MT formation from Golgi, implicating Golgi-originated MT arrays in efficient cell migration (Efimov et al., 2007).
Liu, Zhonghua +2 more
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bicoid RNA localization requires the trans-Golgi network [PDF]
Hereditas, 2019 AbstractBackgroundThe formation of thebicoid(bcd) mRNA gradient is a crucial step for Bcd protein gradient formation inDrosophila. In the past, a microtubule (MT)-based cortical network had been shown to be indispensable forbcdmRNA transport to the posterior.ResultsWe report the identification of a MT-binding protein CLASP/Chb as the first component ...
Xiaoli Cai +2 more
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The role of clathrin in post-golgi trafficking in toxoplasma gondii [PDF]
, 2013 Apicomplexan parasites are single eukaryotic cells with a highly polarised secretory system that contains unique secretory organelles (micronemes and rhoptries) that are required for host cell invasion.
Ferguson, D.J.P. +3 more
core +8 more sources