Results 101 to 110 of about 85,659 (234)

Studies on structure and function of clathrin adaptor proteins [PDF]

, 2004
AP-1 and GGAs (Golgi-localizing, γ-adaptin ear domain homology, ADP-ribosylationfactor (ARF)-bindind proteins) are adaptor proteins of clathrincoated vesicles that mediate transport between the trans-Golgi network (TGN) and endosmoes. ･･･Thesis (Ph.
Shiba Yoko, 芝 陽子
core  

Transforming growth factor-beta targets Formin-like 2 for Angiopoietin-like 4 secretion during the epithelial mesenchymal transition [PDF]

, 2019
Epithelial to Mesenchymal transition (EMT) is a highly dynamic process that plays a crucial role in tumor progression and metastasis. While remodelling of the actin cytoskeleton is a hallmark of EMT, the responsible actin regulating factors are less well
Moussi, Christel Jessica
core   +1 more source

Cargoes move from cis to trans-Golgi compartments and concentrate in the TGN before exiting

EMBO Reports
The classical models of intra-Golgi transport envision a movement of cargoes from cis- to trans-Golgi, followed by their sorting at the trans-Golgi network (TGN).
Marinella Pirozzi, Ilenia Agliarulo, Rosaria Di Martino, Vincenzo Manuel Marzullo, Micaela Quarto, Gabriele Turacchio, Galina V Beznoussenko, Domenico Russo, Alberto Luini, Alexander A Mironov, Seetharaman Parashuraman   +10 more
doaj   +1 more source

Respiratory Syncytial Virus Under the Lens of Structure: From Prefusion Stabilization to Next‐Generation Immunotherapies

iNew Medicine, EarlyView.
This illustration integrates key concepts covered in the review, including high‐risk populations, viral structure, host entry factors, the replication cycle, and licensed antibody‐based prevention strategies. ABSTRACT Respiratory syncytial virus (RSV) is a negative‐sense RNA virus belonging to the genus Orthopneumovirus within the family Pneumoviridae.
Zekai Cheng, Qianqian Wang, Jiachen Zhang, Sandra Chiu   +3 more
wiley   +1 more source

Markers for trans-Golgi membranes and the intermediate compartment localize to induced membranes with distinct replication functions in flavivirus-infected cells [PDF]

, 1999
Replication of the flavivirus Kunjin virus is associated with virus-induced membrane structures within the cytoplasm of infected cells; these membranes appear as packets of vesicles associated with the sites of viral RNA synthesis and as convoluted ...
Bienz K., Chu P. W. G., Chu P. W. G., Coia G., Froshauer S., Fukuda M., Geuze H. J., Grun J. B., Hobman T. C., Hobman T. C., Koonin E. V., Krijnse Locker J., Leary K., Lee J.-Y., Linstedt A. D., Lippincott-Schwartz J., Lippincott-Schwartz J., Lotti L. V., Mackenzie J. M., Mackenzie J. M., Mackenzie J. M., Magliano D., Ng M. L., Rice C. M., Schweizer A., Schweizer A., Slot J. W., Speight G., Speight G., Speight G., Sreenivasan V., Stous G. J., Vaux D., Watzele G., Westaway E. G., Westaway E. G., Westaway E. G., Winkler G.   +37 more
core   +1 more source

Reduction in Synaptic Vesicle Protein Abundance but Increased Amounts of Nsg2 and Lpcat1 in Cerebral Cortices Without the Endosomal SNARE Proteins Vti1a and Vti1b

PROTEOMICS, EarlyView.
ABSTRACT Absence of the endosomal SNAREs vti1a and vti1b results in perinatal death and severe neuronal phenotypes in mice, while lack of one of these proteins results in minor phenotypes. Proteomic differences were investigated to obtain a deeper insight into processes in which vti1a and vti1b are involved.
Julia Gottschalk, Katharina Kotschnew, Julia Hahn, Thomas Patschkowski, Gabriele von Fischer von Mollard   +4 more
wiley   +1 more source

A functional study of AUXILIN-LIKE1 and 2, two putative clathrin uncoating factors in Arabidopsis [PDF]

, 2018
Clathrin-mediated endocytosis (CME) is a cellular trafficking process in which cargoes and lipids are internalized from the plasma membrane into vesicles coated with clathrin and adaptor proteins. CME is essential for many developmental and physiological
Adamowski, Maciek, De Jaeger, Geert, Friml, Jiri, Glanc, Matous, Kania, Urszula, Narasimhan, Madhumitha   +5 more
core   +2 more sources

Differentiation of Trafficking Pathways at Golgi Entry Core Compartments and Post-Golgi Subdomains

Frontiers in Plant Science, 2020
Eukaryotic cells have developed specialized membrane structures called organelles, which compartmentalize cellular functions and chemical reactions. Recent improvements in microscopy and membrane compartment isolation techniques are now sophisticating ...
Yoko Ito, Yohann Boutté
doaj   +1 more source

The Mechanism of NLRP3 Inflammasome Activation and Its Roles in Chronic Rhinosinusitis

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT NLRP3 (NLR family pyrin domain containing 3) is one of the crucial receptors in pathogen recognition receptor (PRR) families which can recognize the pathogen‐associated molecular patterns (PAMPs) and the damage‐associated molecular patterns (DAMPs), thus triggering innate immune response. After NLRP3 activation, it recruits the adaptor protein
Dong‐Lin Li, Yue Li, Yan‐Jie Jiang, Ge‐Hua Zhang, Li‐Hong Chang   +4 more
wiley   +1 more source

An ancestral secretory apparatus in the protozoan parasite Giardia intestinalis [PDF]

, 2003
The protozoan parasite Giardia intestinalis belongs to one of the earliest diverged eukaryotic lineages. This is also reflected in a simple intracellular organization, as Giardia lacks common subcellular compartments such as mitochondria, peroxisomes ...
Hehl, Adrian B., Knopf, Lea G., Li, Yajie, Marti, Matthias, Müller, Norbert, Regös, Attila, Schraner, Elisabeth M., Wild, Peter   +7 more
core   +1 more source