Direct binding of retromer to human papillomavirus type 16 minor capsid protein L2 mediates endosome exit during viral infection. [PDF]
PLoS Pathogens, 2015 Trafficking of human papillomaviruses to the Golgi apparatus during virus entry requires retromer, an endosomal coat protein complex that mediates the vesicular transport of cellular transmembrane proteins from the endosome to the Golgi apparatus or the ...
Andreea Popa +8 more
doaj +1 more source
Assembly and disassembly of the Golgi Complex: two prodesses arranged in a cis to trans direction [PDF]
, 1992 We have studied the disassembly and assembly of two morphologically and functionally distinct parts of the Golgi complex, the cis/middle and trans cisterna/trans network compartments.
Alcalde, José +4 more
core +2 more sources
Fine tuning Exo2, a small molecule inhibitor of secretion and retrograde trafficking pathways in mammalian cells [PDF]
, 2010 The small molecule 4-hydroxy-3-methoxybenzaldehyde (5,6,7,8-tetrahydro[1]benzothieno[2,3- d]pyrimidin-4-yl)hydrazone (Exo2) stimulates morphological changes at the mammalian Golgi and trans-Golgi network that are virtually indistinguishable from those ...
Barr +67 more
core +1 more source
Sphingomyelin synthases regulate protein trafficking and secretion. [PDF]
PLoS ONE, 2011 Sphingomyelin synthases (SMS1 and 2) represent a class of enzymes that transfer a phosphocholine moiety from phosphatidylcholine onto ceramide thus producing sphingomyelin and diacylglycerol (DAG). SMS1 localizes at the Golgi while SMS2 localizes both at
Marimuthu Subathra +2 more
doaj +1 more source
Selective fragmentation of the trans-Golgi apparatus by Rickettsia rickettsii.
PLoS Pathogens, 2020 Fragmentation of the Golgi apparatus is observed during a number of physiological processes including mitosis and apoptosis, but also occurs in pathological states such as neurodegenerative diseases and some infectious diseases.
Karin Aistleitner +3 more
doaj +1 more source
Importance of the N-terminal domain of the Qb-SNARE Vti1p for different membrane transport steps in the yeast endosomal system. [PDF]
PLoS ONE, 2013 SNAREs (soluble N-ethylmaleimide-sensitive factor attachment protein receptor) on transport vesicles and target membranes are crucial for vesicle targeting and fusion.
Michael Gossing +2 more
doaj +1 more source
Vesicular and non-vesicular transport feed distinct glycosylation pathways in the Golgi. [PDF]
, 2013 Newly synthesized proteins and lipids are transported across the Golgi complex via different mechanisms whose respective roles are not completely clear. We previously identified a non-vesicular intra-Golgi transport pathway for glucosylceramide (GlcCer)--
Burke JE +20 more
core +1 more source
Trans-Golgi network delivery of synaptic proteins in synaptogenesis [PDF]
Journal of Cell Science, 2004 Synapse formation, stabilization and maintenance comprise several remarkably precise and rapid stages. The initial steps involve delivery to the site of initial contact between axon and dendrite of transport carriers containing several sets of synaptic proteins necessary for proper synaptic function.
Vladimir, Sytnyk +3 more
openaire +2 more sources
High-resolution mapping reveals topologically distinct cellular pools of phosphatidylserine [PDF]
, 2011 Phosphatidylserine (PS) plays a central role in cell signaling and in the biosynthesis of other lipids. To date, however, the subcellular distribution and transmembrane topology of this crucial phospholipid remain ill-defined. We transfected cells with a
Fairn, Gregory D. +7 more
core +2 more sources
Proteomic dissection of the Arabidopsis Golgi and trans-Golgi network
Frontiers in Plant Science, 2013 The plant Golgi apparatus and trans-Golgi network are major functional hubs within the plant cell and are involved in a diverse and vital series of functions to maintain plant growth and development.
Harriet Tempé Parsons +2 more
doaj +1 more source