Results 101 to 110 of about 292,424 (340)

Liver transplantation across ABO blood groups [PDF]

open access: yes, 1986
Six hundred seventy-one first, second, and third orthotopic liver allografts in 520 patients were reviewed to determine the effect of donor-recipient mismatches or incompatibility for the ABO blood group on graft survival. A significant advantage for ABO
Esquivel, CO   +5 more
core  

Liver transplantation before 1 year of age [PDF]

open access: yes, 1987
Since 1981, 20 infants younger than 1 year of age received 26 orthotopic liver transplants. Immunosuppression was with cyclosporine and corticosteroids. Thirteen (65%) of the reciplents were discharged from the hospital.
Ascher   +18 more
core   +1 more source

Annexin A13 Protects Against Acute Kidney Injury by Inactivating TGF‐β/Smad3 Signaling

open access: yesAdvanced Science, EarlyView.
ANXA13 is negatively regulated by Smad3 and exerts its protective role in AKI by inactivating TGF‐β/Smad3 signaling and Smad3‐p21 cell cycle arrest pathway through binding to TβRI, inhibiting the interaction between TβRI and TβRII, thereby suppressing TβRI phosporylation.
Jiaxiao Li   +12 more
wiley   +1 more source

From Structure to Function: Analysis of the First Monomeric Pyridoxal-5′-Phosphate-Dependent Transaminase from the Bacterium Desulfobacula toluolica

open access: yesBiomolecules
The first monomeric pyridoxal-5′-phosphate (PLP)-dependent transaminase from a marine, aromatic-compound-degrading, sulfate-reducing bacterium Desulfobacula toluolica Tol2, has been studied using structural, kinetic, and spectral methods.
Alina K. Bakunova   +6 more
doaj   +1 more source

Renal and Hepatic Dysfunction in Malaria Patients in Minna, North Central Nigeria [PDF]

open access: yes, 2009
Information on kidney and liver involvement in malaria in Africa is still very scanty. Kidney and liver functions were assessed in 70 malaria patients using serum levels of creatinine and urea and urinary protein levels as test indicators of kidney ...
Ogbadoyi, EO, Tsado, RD
core   +1 more source

Icaritin Ameliorates Cisplatin‐Induced Mitochondrial Metabolic Dysfunction‐Associated Nephrotoxicity and Synergistically Potentiates Its Antitumor Efficacy

open access: yesAdvanced Science, EarlyView.
In this study, scRNA‐seq and chemoproteomics are integrated to characterize CDDP‐bound proteins at single‐cell resolution in tumor‐bearing mice. Additionally, the research demonstrates that ICA alleviates CDDP‐induced nephrotoxicity while enhancing its chemotherapeutic efficacy.
Piao Luo   +19 more
wiley   +1 more source

Computational Design and Glycoengineering of Interferon‐Lambda for Nasal Prophylaxis Against Respiratory Viruses

open access: yesAdvanced Science, EarlyView.
This study presents an engineered human interferon‐lambda (hIFN‐λ) as an intranasal prophylactic against respiratory viruses. By combining AI‐guided backbone redesign and glycoengineering, the authors developed a thermostable, protease‐resistant, and scalable variant with improved mucosal penetration.
Jeongwon Yun   +12 more
wiley   +1 more source

Rare presentation of an atrial myxoma in an adolescent patient: A case report and literature review [PDF]

open access: yes, 2018
BACKGROUND: Cardiac tumors are uncommon in the pediatric population. When present, cardiac manifestations stem from the tumor causing inflow or outflow obstruction.
Anwar, Shafkat   +6 more
core   +3 more sources

Perfluorooctanoic Acid Exposure Causes Macrophage Ammonia Retention and Induces Spontaneous Miscarriages

open access: yesAdvanced Science, EarlyView.
PFOA exposure induces pregnancy loss by promoting glutaminolysis, which further causes ammonia accumulation in macrophages. Cellular ammonia retention results in damage to mitochondria and lysosomes, which leads to cell death eventually. Impaired lysosomes also decrease the secretion of the Cathepsin B (CTSB), and attenuate macrophage infiltration and ...
Yongbo Zhao   +6 more
wiley   +1 more source

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